Dynamic imaging of functionalized multi-walled carbon nanotube systemic circulation and urinary excretion.

Lacerda, L., Soundararajan, A., Singh, R., Pastorin, G., Al-Jamal, K.T., Turton, J.A., Fredrik, P., Herrero, M.A., Liu, S., Bao, A., Emfietzoglou, D., Mather, S.J., Phillips, W.T., Prato, M., Bianco, A., Goins, B. and Kostarelos, K. (2008) Dynamic imaging of functionalized multi-walled carbon nanotube systemic circulation and urinary excretion. Advanced Materials, 20 (2). pp. 225-230. 10.1002/adma.200890002.

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DOI: 10.1002/adma.200890002

Abstract

Intravenously administered multi-walled carbon nanotubes, functionalized with DTPA and radiolabeled with Indium-111, were dynamically tracked in vivo using a microSingle Photon Emission Tomography scanner. Imaging showed that nanotubes enter the systemic blood circulation and within 5 min begin to permeate through the renal glomerular filtration system into the bladder.

Item Type:Article
Additional Information:Full text available electronically from the School of Pharmacy Library.
Uncontrolled Keywords:Biomedical applications;Carbon nanotubes, multiwalled;Nanomaterials
Departments, units and centres:Department of Pharmacology > Centre for Toxicology
ID Code:1219
Journal or Publication Title:Advanced Materials
Deposited By:Library Staff
Deposited On:23 Jun 2009 10:48
Last Modified:04 May 2012 10:38

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