Lacotte, S., Garcia, A., Decossas, M., Al-Jamal, W.T., Li, S. and Kostarelos, K. (2008) Interfacing functionalized carbon nanohorns with primary phagocytic cells. Advanced Materials, 20 (2). pp. 2421-2426. 10.1002/adma.200702753.
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Functionalized carbon nanohorns (f-CNH) are uptaken by macrophages, without affecting cell viability. f-CNH induce the production of reactive oxygen species and of pro-inflammatory cytokines. The level of inflammation, although moderate, should be taken into consideration when using f-CNH for drug delivery. However, it could be exploited as an intrinsic f-CNH adjuvant function for biomedical applications requiring some activation of the immune system.
|Additional Information:||Full text available electronically from the School of Pharmacy Library.|
|Uncontrolled Keywords:||carbon nanostructures;cells;cytotoxicity;drug delivery|
|Departments, units and centres:||Department of Pharmaceutics > Centre for Drug Delivery Research|
|Journal or Publication Title:||Advanced Materials|
|Deposited By:||Library Staff|
|Deposited On:||29 Jun 2009 14:40|
|Last Modified:||04 May 2012 10:32|
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