Lacotte, S., Garcia, A., Decossas, M., Al-Jamal, W.T., Li, S. and Kostarelos, K. (2008) Interfacing functionalized carbon nanohorns with primary phagocytic cells. Advanced Materials, 20 (2). pp. 2421-2426. 10.1002/adma.200702753.
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Abstract
Functionalized carbon nanohorns (f-CNH) are uptaken by macrophages, without affecting cell viability. f-CNH induce the production of reactive oxygen species and of pro-inflammatory cytokines. The level of inflammation, although moderate, should be taken into consideration when using f-CNH for drug delivery. However, it could be exploited as an intrinsic f-CNH adjuvant function for biomedical applications requiring some activation of the immune system.
| Item Type: | Article |
|---|---|
| Additional Information: | Full text available electronically from the School of Pharmacy Library. |
| Uncontrolled Keywords: | carbon nanostructures;cells;cytotoxicity;drug delivery |
| Departments, units and centres: | Department of Pharmaceutics > Centre for Drug Delivery Research |
| ID Code: | 1252 |
| Journal or Publication Title: | Advanced Materials |
| Deposited By: | Library Staff |
| Deposited On: | 29 Jun 2009 14:40 |
| Last Modified: | 04 May 2012 10:32 |
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