Synthesis of a novel C2/C2′-aryl-substituted pyrrolo[2,1-c][1,4]benzodiazepine dimer prodrug with improved water solubility and reduced DNA reaction rate.

Howard, P.W., Chen, Z., Gregson, S.J., Masterson, L., Tiberghien, A.C., Cooper, N., Fang, M., Coffils, M.J., Hartley, J.A. and Thurston, D.E. (2009) Synthesis of a novel C2/C2′-aryl-substituted pyrrolo[2,1-c][1,4]benzodiazepine dimer prodrug with improved water solubility and reduced DNA reaction rate. Biorganic and Medicinal Chemistry Letters, 19 (22). pp. 6463-6466. 10.1016/j.bmcl.2009.09.012.

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DOI: 10.1016/j.bmcl.2009.09.012


Item Type:Article
Additional Information:Full text available electronically from the School of Pharmacy Library.
Departments, units and centres:Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry
ID Code:1514
Journal or Publication Title:Biorganic and Medicinal Chemistry Letters
Deposited By:Library Staff
Deposited On:13 Apr 2010 10:49
Last Modified:18 Jun 2010 12:00

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