Moses, J., Ritson, D., Zhang, F., Lombardo, C.M., Haider, S.M., Oldham, N. and Neidle, S. (2010) A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands. Organic and Biomolecular Chemistry, 8 (13). pp. 2926-2930. 10.1039/c005055e.
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DOI: 10.1039/c005055e
Abstract
Described is the structure-based design and synthesis of a series of tris-triazole G-quadruplex binding ligands utilising the copper catalysed azide-alkyne 'click' reaction. The results of G-quadruplex stabilisation by the ligands are reported and discussed.
| Item Type: | Article |
|---|---|
| Additional Information: | Full text available electronically from the School of Pharmacy Library. |
| Departments, units and centres: | Department of Pharmaceutical and Biological Chemistry > Cancer Research UK Biomolecular Structure Group |
| ID Code: | 1603 |
| Journal or Publication Title: | Organic and Biomolecular Chemistry |
| Deposited By: | Library Staff |
| Deposited On: | 24 Jun 2010 15:10 |
| Last Modified: | 04 Feb 2011 15:32 |
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