An Expedient Entry into the a-Mercaptodiketopiperazine Nucleus

Hilton, S.T., Motherwell, W.B. and Selwood, D.L. (2004) An Expedient Entry into the a-Mercaptodiketopiperazine Nucleus. Synlett, 14 . pp. 2609-2611. 10.1055/s-2004-834823.

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DOI: 10.1055/s-2004-834823

Abstract

A novel approach to the a-mercaptodiketopiperazine nucleus is reported, which involved a three-component reaction of a number of amines with ethyl glyoxalate and para-methoxybenzylmercaptan. The subsequent products were readily elaborated to the monothiodiketopiperazine core structure. .

Item Type:Article
Uncontrolled Keywords:epidithiodiketopiperazine - multicomponent reactions - thiols - imines - sulfur
Departments, units and centres:Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry
ID Code:2070
Journal or Publication Title:Synlett
Deposited By:Library Staff
Deposited On:06 May 2011 12:57
Last Modified:06 May 2011 12:57

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