Calorimetry for polymorph detection

Gaisford, S. and O'Neill, M.A.A. (2007) Calorimetry for polymorph detection. European Pharmaceutical Review, 12 (2). pp. 70-74.

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Abstract

Characterising the properties of a material, understanding how these properties change in relation to local environment and quantifying potential interactions with other species are facets central to any drug development programme. Not understanding and, more importantly, not controlling these factors can have serious consequences for a pharmaceutical, from irreproducible processing to poor bioavailability, product instability and, worse, patentability. Properties that may be characterised include solubility, dissolution rate, stability (in combination with other excipients and as a function of relative humidity and temperature) and per cent crystallinity (or amorphous content).

Item Type:Article
Departments, units and centres:Department of Pharmaceutics > Department of Pharmaceutics
ID Code:2100
Journal or Publication Title:European Pharmaceutical Review
Deposited By:Library Staff
Deposited On:20 May 2011 09:26
Last Modified:20 May 2011 09:26

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