Watts, J. and Thomson, A.M. (2005) Excitatory and inhibitory connections show selectivity in the neocortex. Journal of Physiology, 562 (1). pp. 89-97. 10.1113/jphysiol.2004.076984.
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Official URL: http://jp.physoc.org/cgi/content/abstract/562/1/89
The cerebral cortex is pivotal in information processing and higher brain function and its laminar structure of six distinct layers, each in receipt of a different constellation of inputs, makes it important to identify connectivity patterns and distinctions between excitatory and inhibitory pathways. The ‘feedforward’ projections from layer 4–3 and from 3–5 target pyramidal cells and to lesser degrees interneurones. ‘Feedback’ projections from layer 5–3 and from 3–4, on the other hand, mainly target interneurones. Understanding the microcircuitry may give some insight into the computation and information processing performed in this brain region.
|Departments, units and centres:||Department of Pharmacology > Department of Pharmacology|
|Journal or Publication Title:||Journal of Physiology|
|Deposited By:||Library Staff|
|Deposited On:||21 Nov 2006|
|Last Modified:||11 Nov 2011 15:57|
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