Induction of a Stress Protein in Developing Cell Cultures of the Rat Cerebellum

Pearce, B.R., Dutton, G.R. and White, F.P. (2006) Induction of a Stress Protein in Developing Cell Cultures of the Rat Cerebellum. Journal of Neurochemistry, 41 (1). pp. 291-294. 10.1111/j.1471-4159.1983.tb11844.x.

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DOI: 10.1111/j.1471-4159.1983.tb11844.x

Abstract

We examined the ability of developing cerebellar cell cultures to synthesize a 71,000 MW stress protein (SP71) in response to heat shock and Cd2+ treatment. The induction of SP71 synthesis appeared to be dependent on both the age of the culture and the stressor used. Heat shock induced SP71 synthesis in freshly prepared cells and in cell cultures at each age examined, whereas Cd2+ was effective only in cultures at 7 days of age and older. These findings are discussed with reference to the development of various cell types in these cultures.

Item Type:Article
Departments, units and centres:Department of Pharmacology > Department of Pharmacology
ID Code:2429
Journal or Publication Title:Journal of Neurochemistry
Deposited By:Library Staff
Deposited On:10 Nov 2011 14:21
Last Modified:10 Nov 2011 14:21

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