Evaluation of generation 2 and 3 poly(propylenimine) dendrimers for the potential cellular delivery of antisense oligonucleotides targeting the epidermal growth factor receptor.

Hollins, A.J., Benboubetra, M., Omidi, Y., Zinselmeyer, B.H., Schatzlein, A.G., Uchegbu, I.F. and Akhtar, S. (2004) Evaluation of generation 2 and 3 poly(propylenimine) dendrimers for the potential cellular delivery of antisense oligonucleotides targeting the epidermal growth factor receptor. Pharmaceutical Research, 21 (3). pp. 458-466. 10.1023/B:PHAM.0000019300.04836.51.

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DOI: 10.1023/B:PHAM.0000019300.04836.51

Abstract

G2 and G3 poly(propylenimine) dendrimers markedly improved the delivery and activity of ODNs and thus may represent general reagents for the delivery of ODNs to cells in culture.

Item Type:Article
Departments, units and centres:Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry
ID Code:2461
Journal or Publication Title:Pharmaceutical Research
Deposited By:Library Staff
Deposited On:11 Nov 2011 17:10
Last Modified:11 Nov 2011 17:10

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