Whalley, B.J., Stephens, G.J. and Constanti, A. (2009) Investigation of the effects of the novel anticonvulsant compound carisbamate (RWJ-333369) on rat piriform cortical neurones in vitro. British Journal of Pharmacology, 156 (6). pp. 994-1008. 10.1111/j.1476-5381.2008.00110.x.
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Official URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697724/?tool=EBI
DOI: 10.1111/j.1476-5381.2008.00110.x
Abstract
Carisbamate blocked evoked action potentials use-dependently, consistent with a primary action on Na+ channels and increased Cl(-) conductances presynaptically and, under certain conditions, postsynaptically to selectively depress excitatory neurotransmission in piriform cortical layer Ia-afferent terminals.
| Item Type: | Article |
|---|---|
| Departments, units and centres: | Department of Pharmacology > Department of Pharmacology |
| ID Code: | 2503 |
| Journal or Publication Title: | British Journal of Pharmacology |
| Deposited By: | Library Staff |
| Deposited On: | 24 Nov 2011 15:11 |
| Last Modified: | 24 Nov 2011 15:12 |
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