Whalley, B.J., Stephens, G.J. and Constanti, A. (2009) Investigation of the effects of the novel anticonvulsant compound carisbamate (RWJ-333369) on rat piriform cortical neurones in vitro. British Journal of Pharmacology, 156 (6). pp. 994-1008. 10.1111/j.1476-5381.2008.00110.x.
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Carisbamate blocked evoked action potentials use-dependently, consistent with a primary action on Na+ channels and increased Cl(-) conductances presynaptically and, under certain conditions, postsynaptically to selectively depress excitatory neurotransmission in piriform cortical layer Ia-afferent terminals.
|Departments, units and centres:||Department of Pharmacology > Department of Pharmacology|
|Journal or Publication Title:||British Journal of Pharmacology|
|Deposited By:||Library Staff|
|Deposited On:||24 Nov 2011 15:11|
|Last Modified:||24 Nov 2011 15:12|
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