Ceramide: does it matter for T cells?

Adam, D., Heinrich, M., Kabelitz, D. and Schutze, S. (2002) Ceramide: does it matter for T cells? Trends in Immunology, 23 (1). p. 1. 10.1016/S1471-4906(01)02091-9.

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DOI: 10.1016/S1471-4906(01)02091-9

Abstract

Ceramide and its derivatives have been implicated in cellular activation, differentiation, survival and death. Although the main biological function of ceramide appears to be linked to its potency to induce cell death, its actual relevance as a regulator of cell death has been the subject of controversial discussions. Here, we discuss the significance of ceramide in T-cell biology, with special emphasis on the regulation of T-cell receptor expression, growth arrest, costimulation and death.

Item Type:Article
Departments, units and centres:Department of Pharmaceutical and Biological Chemistry > Centre for Pharmacognosy and Phytotherapy
ID Code:2687
Journal or Publication Title:Trends in Immunology
Deposited By:Library Staff
Deposited On:19 Jan 2012 15:36
Last Modified:19 Jan 2012 15:37

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