Frei, B., Heinrich, M., Herrmann, D., Orjala, J., Schmitt, J. and Sticher, O. (1998) Phytochemical and Biological Investigation ofBegonia heracleifolia. Planta Medica, 64 (04). pp. 385-386. 10.1055/s-2006-957460.
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From the rhizomes of Begonia heracleifolia six known cucurbitacins (1-6) were isolated. Based on spectral data (1D and 2D1H-, 13C-NMR, ESI- and CI-MS) the structures were established as cucurbitacin B (1), cucurbitacin D (2), 23,24-dihydrocucurbitacin D (3), 23,24-dihydrocucurbitacin F (4), 2-O-β-glucopyranosyl-cucurbitacin B (5), and 2-O-β-glucopyranosyl-cucurbitacin D (6). Four of them (3-6) were so far not reported as constituents of Begonia spp. Varyingly strong antiproliferative activity towards tumor and immune cells was observed for three compounds (1 -3), due to different structural features.
|Departments, units and centres:||Department of Pharmaceutical and Biological Chemistry > Centre for Pharmacognosy and Phytotherapy|
|Journal or Publication Title:||Planta Medica|
|Deposited By:||Library Staff|
|Deposited On:||19 Jan 2012 17:41|
|Last Modified:||19 Jan 2012 17:41|
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