Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum–phenanthroline complex

Reed, J.E., Neidle, S. and Vilar, R. (2007) Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum–phenanthroline complex. Chemical Communications (42). pp. 4366-4368. 10.1039/b709898g.

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DOI: 10.1039/b709898g

Abstract

Two new mono-substituted phenanthroline ligands and their platinum(ii) square planar complexes have been prepared; one of the complexes has been shown to induce a high degree of quadruplex DNA stabilisation and to inhibit telomerase

Item Type:Article
Departments, units and centres:Department of Pharmaceutical and Biological Chemistry > Centre for Pharmacognosy and Phytotherapy
ID Code:2738
Journal or Publication Title:Chemical Communications
Deposited By:Library Staff
Deposited On:20 Jan 2012 14:53
Last Modified:20 Jan 2012 14:53

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