Reed, J.E., Neidle, S. and Vilar, R. (2007) Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum-phenanthroline complex. Chemical Communications (42). pp. 4366-4368. 10.1039/B709898G .
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Two new mono-substituted phenanthroline ligands and their platinum(II) square planar complexes have been prepared; one of the complexes has been shown to induce a high degree of quadruplex DNA stabilisation and to inhibit telomerase.
|Departments, units and centres:||Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry|
|Journal or Publication Title:||Chemical Communications|
|Deposited By:||Library Staff|
|Deposited On:||20 Jan 2012 15:00|
|Last Modified:||20 Jan 2012 15:00|
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