Synthesis of a novel C2-aryl substituted 1,2-unsaturated pyrrolobenzodiazepine

Kang, G-D., Howard, P.W. and Thurston, D.E. (2003) Synthesis of a novel C2-aryl substituted 1,2-unsaturated pyrrolobenzodiazepine. Chemical Communications (14). pp. 1688-1689. 10.1039/B303274D.

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DOI: 10.1039/B303274D

Abstract

A novel C2-aryl 1,2-unsaturated PBD (14) has been prepared via an enol triflate intermediate (8). The regiochemistry of triflation is dependent upon the point at which the reaction is performed during the synthetic route.

Item Type:Article
Departments, units and centres:Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry
ID Code:2916
Journal or Publication Title:Chemical Communications
Deposited By:Library Staff
Deposited On:08 Mar 2012 11:44
Last Modified:08 Mar 2012 11:44

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