Cooper, N., Hagan, D.R., Tiberghien, A., Ademefun, T., Matthews, C.S., Howard, P.W. and Thurston, D.E. (2002) Synthesis of novel C2-aryl pyrrolobenzodiazepines (PBDs) as potential antitumour agents. Chemical Communications (16). pp. 1764-1765. 10.1039/B205136B.
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Three novel C2-aryl substituted pyrrolobenzodiazepines (PBDs) have been synthesised and evaluated in a number of cell lines revealing selective cytotoxicity at the sub-nanomolar level towards melanoma and ovarian cancer cell lines.
|Departments, units and centres:||Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry|
|Journal or Publication Title:||Chemical Communications|
|Deposited By:||Library Staff|
|Deposited On:||08 Mar 2012 16:51|
|Last Modified:||08 Mar 2012 16:51|
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