Antiprotozoal alkaloids from Galanthus trojanus

Kaya, G.I., Sarıkaya, B., Onur, M.A., Somer, N.U., Viladomat, F., Codina, C., Bastida, J., Lauinger, I.L., Kaiser, M. and Tasdemir, D. (2011) Antiprotozoal alkaloids from Galanthus trojanus. Phytochemistry Letters, 4 (3). pp. 301-305. 10.1016/j.phytol.2011.05.008.

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DOI: 10.1016/j.phytol.2011.05.008

Abstract

Two new alkaloid N-oxides, 1-O-acetyldihydromethylpseudolycorine N-oxide, and 11-hydroxyvittatine N-oxide, ten known alkaloids; arolycoricidine, haemanthamine, O-methylnorbelladine, narcidine, dihydrolycorine, 8-O-demethylmaritidine, stylopine and protopine, nicotinic acid and tyramine were isolated from Galanthus trojanus A.P. Davis & N. Özhatay (Amaryllidaceae). The chemical structures of the isolates were elucidated by UV, IR, MS, CD, 1D and 2D NMR experiments. The in vitro antiprotozoal and cytotoxic potentials of the compounds were also evaluated.

Item Type:Article
Uncontrolled Keywords:Alkaloid N-oxides; Amaryllidaceae; Antimalarial activity; Galanthus trojanus
Departments, units and centres:Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry
ID Code:2951
Journal or Publication Title:Phytochemistry Letters
Deposited By:Library Staff
Deposited On:09 Mar 2012 16:21
Last Modified:09 Mar 2012 16:21

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