Solid-phase synthesis of C-terminal thio-linked glycopeptides

Malkinson, J.P. and Falconer, R.A. (2002) Solid-phase synthesis of C-terminal thio-linked glycopeptides. Tetrahedron Letters, 43 (52). pp. 9549-9552. 10.1016/S0040-4039(02)02419-X.

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DOI: 10.1016/S0040-4039(02)02419-X

Abstract

A solid-phase Mitsunobu reaction between a resin-bound 1-thiosugar and an N-Fmoc protected amino alcohol was successfully employed for thio-linked glycopeptide synthesis. Facile cleavage and deprotection in one step afforded the target glycopeptide in good yield and purity

Item Type:Article
Departments, units and centres:Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry
ID Code:2982
Journal or Publication Title:Tetrahedron Letters
Deposited By:Library Staff
Deposited On:16 Mar 2012 10:07
Last Modified:16 Mar 2012 10:07

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