Aislamiento de zederona de los rizomas de Zingiber zerumbet y su actividad antiestafilocócica

Kader, M.G., Habib, M.R., Nikkon, F., Yeasmin, T., Rahman, M.M. and Gibbons, S. (2010) Aislamiento de zederona de los rizomas de Zingiber zerumbet y su actividad antiestafilocócica. Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas , 9 (1). pp. 63-68.

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Abstract

A sesquiterpene, zederone (1), was isolated from the crude ethanolic extract of the rhizomes of Zingiber zerumbet (L.) Smith. It is the first time report of isolation of this compound from the genus Zingiber. Its structure was established by a series of spectral data including high-field NMR (both 1D and 2D) and MS. The antibacterial activity of this compound was determined against a number of multi-drug resistant and methicillin-resistant Staphylococcus aureus strains (SA1199B, ATCC25923, XU212, RN4220 and EMRSA15) and minimum inhibitory concentration (MIC) values were found to be in the range of 64-128 μg/ml.

Item Type:Article
Uncontrolled Keywords:Antibacterial; Staphylococcus aureus; Zederone; Zingiber zerumbet; Zingiberaceae
Departments, units and centres:Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry
ID Code:3066
Journal or Publication Title:Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas
Deposited By:Library Staff
Deposited On:23 Mar 2012 14:28
Last Modified:23 Mar 2012 14:44

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