Zinselmeyer, B.H., Mackay, S.P., Schatzlein, A.G. and Uchegbu, I.F. (2002) The lower-generation polypropylenimine dendrimers are effective gene-transfer agents. Pharmaceutical research, 19 (7). pp. 960-967.
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Abstract
The generation 2 polypropylenimine dendrimer combines a sufficient level of DNA binding with a low level of cell cytoxicity to give it optimum in vitro gene transfer activity.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | cultureddnadna administration & dosagedna geneticsdrug delivery systemsdrug delivery systems methodsescherichia coligene transfer techniqueshumansiminesimines administration & dosageimines chemistryimines toxicitymodelsmolecularpolypropylenespolypropylenes administration & dosagepolypropylenes chemistrypolypropylenes toxicitytumor cells |
| Departments, units and centres: | Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry |
| ID Code: | 3086 |
| Journal or Publication Title: | Pharmaceutical research |
| Deposited By: | Library Staff |
| Deposited On: | 20 Apr 2012 14:54 |
| Last Modified: | 20 Apr 2012 14:58 |
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