Identification of polymorphisms in the malic enzyme 1, NADP(+)-dependent, cytosolic and nuclear receptor subfamily 0, group B, member 2 genes and their associations with meat and carcass quality traits in commercial Angus cattle

Gill, J.L., Bishop, S.C., McCorquodale, C., Williams, J. L. and Wiener, P. (2011) Identification of polymorphisms in the malic enzyme 1, NADP(+)-dependent, cytosolic and nuclear receptor subfamily 0, group B, member 2 genes and their associations with meat and carcass quality traits in commercial Angus cattle. Animal Genetics, 43 (1). pp. 88-92. 10.1111/j.1365-2052.2011.02216.x.

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DOI: 10.1111/j.1365-2052.2011.02216.x

Abstract

Genes involved in the physiological control of energy and triglyceride synthesis, such as malic enzyme 1, NADP(+)-dependent, cytosolic (ME1) and nuclear receptor subfamily 0, group B, member 2 (NR0B2), are key candidates that may have effects on meat and carcass quality traits. These genes were sequenced in Aberdeen Angus beef cattle, and the possibility of associations between SNPs and economically important carcass and meat quality traits was tested. Six novel SNPs, five in ME1 and one in NR0B2, were identified. A SNP in exon eight of ME1 resulted in a non-synonymous amino acid change from valine to isoleucine. Phenotypic data were recorded on 536 commercial Aberdeen Angus-cross beef cattle, which comprised 28 carcass quality, tenderness and sensory traits. The majority of the SNPs were associated with at least one of these traits, including an association between the NR0B2 SNP and fat class, and associations between at least one of the ME1 SNPs and eye muscle area, sirloin weight before maturation, sirloin steak tail length, and juiciness.

Item Type:Article
Uncontrolled Keywords:candidate gene; malic enzyme 1; ME1; meat quality; NROB2; nuclear receptor subfamily 0 group B member 2
Departments, units and centres:Department of Pharmacology > Department of Pharmacology
ID Code:3177
Journal or Publication Title:Animal Genetics
Deposited By:Library Staff
Deposited On:04 May 2012 16:19
Last Modified:04 May 2012 16:19

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