Rapid detection of `rare' actinomycetes in environmental samples

Gathogo, E.W.N., Waugh, A.C.W., Perić-Concha, N., Redpath, M.B. and Long, P.F. (2004) Rapid detection of `rare' actinomycetes in environmental samples. Biotechnology Letters, 26 (11). pp. 897-900. 10.1023/B:bile.0000025899.96174.7d.

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DOI: 10.1023/B:bile.0000025899.96174.7d


Natural products continue to be a useful source of new leads for the pharmaceutical industry. Actinomycetes are prolific producers of natural products and one strategy to increase the possibility of discovering novel chemical entities is to screen actinomycetes considered 'rare' in the environment and previously under-represented in natural product screening collections. We describe a method using bacteriophage as a marker to detect these actinomycetes in environmental samples. This method allows samples to be pre-screened for the presence of target actinomycetes before lengthy isolation programmes are undertaken.

Item Type:Article
Uncontrolled Keywords:Actinomycetes; Antibiotics; Bacteriophage; Detection
Departments, units and centres:Department of Pharmaceutics > Department of Pharmaceutics
ID Code:3219
Journal or Publication Title:Biotechnology Letters
Deposited By:Library Staff
Deposited On:11 May 2012 17:52
Last Modified:11 May 2012 17:52


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