A revised nomenclature for the human and rodent α-tubulin gene family

Khodiyar, V.K., Maltais, L.J., Sneddon, K.M., Smith, J.R., Shimoyama, M., Cabral, F., Dumontet, C., Dutcher, S.K., Harvey, R.J., Lafanechere, L., Murray, J.M., Nogales, E., Piquemal, D., Stanchi, F., Povey, S. and Lovering, R.C. (2007) A revised nomenclature for the human and rodent α-tubulin gene family. Genomics, 90 (2). pp. 285-289. 10.1016/j.ygeno.2007.04.008 .

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DOI: 10.1016/j.ygeno.2007.04.008


An essential component of microtubules, α-tubulin is also a multigene family in many species. An orthology-based nomenclature for this gene family has previously been difficult to assign due to incomplete genome builds and the high degree of sequence similarity between members of this family. Using the current genome builds, sequence analysis of human, mouse, and rat α-tubulin genes has enabled an updated nomenclature to be generated. This revised nomenclature provides a unified language for the discussion of these genes in mammalian species; it has been approved by the gene nomenclature committees of the three species and is supported by researchers in the field

Item Type:Article
Departments, units and centres:Department of Pharmacology > Department of Pharmacology
ID Code:865
Journal or Publication Title:Genomics
Deposited By:Library Staff
Deposited On:28 Jan 2008 11:30
Last Modified:13 Oct 2011 16:06

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