A Glycosynthase Catalyst for the Synthesis of Flavonoid Glycosides (Communication)

Yang, M., Davies, G.J. and Davis, B.G. (2007) A Glycosynthase Catalyst for the Synthesis of Flavonoid Glycosides (Communication). Angewandte Chemie International Edition, 46 (21). pp. 3885-3888. 10.1002/anie.200604177.

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DOI: 10.1002/anie.200604177

Abstract

Mutant exposed! The synthetic utility of glycosynthase mutant enzymes has been expanded to allow the use of lipophilic acceptors, such as flavonoids, at rates comparable with those of natural glycosyltransferases. Sequential biocatalysis allows access to both di- and monosaccharide-modified products as well as natural product glycoflavonoids

Item Type:Article
Additional Information:Full text available electronically from the School of Pharmacy Library
Uncontrolled Keywords:biocatalysis;carbohydrates;flavonoids;glycosyltransferases;glycosynthases
Departments, units and centres:Department of Pharmaceutical and Biological Chemistry > Department of Pharmaceutical and Biological Chemistry
ID Code:915
Journal or Publication Title:Angewandte Chemie International Edition
Deposited By:Library Staff
Deposited On:13 May 2008 09:17
Last Modified:07 Oct 2011 15:53

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