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Number of items: 73.

Jones, B.E., Basit, A.W. and Tuleu, C. (2012) The disintegration behaviour of capsules in fed subjects: A comparison of hypromellose (carrageenan) capsules and standard gelatin capsules. International Journal of Pharmaceutics, 424 (1-2). pp. 40-43. /10.1016/j.ijpharm.2011.12.034.

Buanz, A.B., Saunders, M., Basit, A.W. and Gaisford, S. (2011) Preparation of Personalized-dose Salbutamol Sulphate Oral Films with Thermal Ink-Jet Printing. Pharmaceutical Research . 10.1007/s11095-011-0450-5.

Liu, F., Merchant, H.A., Kulkarni, R.P., Alkademi, M. and Basit, A.W. (2011) Evolution of a physiological pH6.8 bicarbonate buffer system: Application to the dissolution testing of enteric coated products. European Journal of Pharmaceutics and Biopharmaceutics, 78 (1). pp. 151-157. 10.1016/j.ejpb.2011.01.001 .

Merchant, H.A., McConnell, E.L., Liu, F., Ramaswamy, C., Kulkarni, R.P., Basit, A.W. and Murdan, S. (2011) Assessment of gastrointestinal pH, fluid and lymphoid tissue in the guinea pig, rabbit and pig, and implications for their use in drug development. European Journal of Pharmaceutical Sciences, 42 (1-2). pp. 3-10. doi:10.1016/j.ejps.2010.09.019.

Freire, A.C., Basit, A.W., Choudhary, R., Piong, C.W. and Merchant, H.A. (2011) Does sex matter? The influence of gender on gastrointestinal physiology and drug delivery. International Journal of Pharmaceutics, 415 (1-2). pp. 15-28. 10.1016/j.ijpharm.2011.04.069.

Alhnan, M.A., Murdan, S. and Basit, A.W. (2011) Encapsulation of poorly soluble basic drugs into enteric microparticles: A novel approach to enhance their oral bioavailability. International Journal of Pharmaceutics, 416 (1). pp. 55-60. 10.1016/j.ijpharm.2011.05.079.

Alhnan, M.A. and Basit, A.W. (2011) Engineering polymer blend microparticles: An investigation into the influence of polymer blend distribution and interaction. European Journal of Pharmaceutical Sciences, 42 (1-2). pp. 30-36. doi:10.1016/j.ejps.2010.10.003.

Varum, F.J.O., Veiga, F., Sousa, J.S. and Basit, A.W. (2011) Mucoadhesive platforms for targeted delivery to the colon. International Journal of Pharmaceutics, 420 (1). pp. 11-19. 10.1016/j.ijpharm.2011.08.006.

Varum, F.J.O., Veiga, F., Sousa, J.S. and Basit, A.W. (2011) Mucus thickness in the gastrointestinal tract of laboratory animals. Journal of Pharmacy and Pharmacology, 64 (2). pp. 218-227. 10.1111/j.2042-7158.2011.01399.x.

Ashiru, D.A.I., Karu, K., Zloh, M., Patel, R. and Basit, A.W. (2011) Relative quantification of polyethylene glycol 400 excreted in the urine of male and female volunteers by direct injection electrospray-selected ion monitoring mass spectrometry. International Journal of Pharmaceutics, 414 (1-2). pp. 35-41. 10.1016/j.ijpharm.2011.04.061.

Alhnan, M.A., Kidia, E. and Basit, A.W. (2011) Spray-drying enteric polymers from aqueous solutions: A novel, economic, and environmentally friendly approach to produce pH-responsive microparticles. European Journal of Pharmaceutics and Biopharmaceutics, 79 (2). pp. 432-439. 10.1016/j.ejpb.2011.03.015.

Ashiru-Oredope, D.A.I., Patel, N.A., Forbes, B., Patel, R. and Basit, A.W. (2011) The effect of polyoxyethylene polymers on the transport of ranitidine in Caco-2 cell monolayers. International Journal of Pharmaceutics, 409 (1-2). pp. 164-168. 10.1016/j.ijpharm.2011.02.059.

Liu, F., Moreno, P. and Basit, A.W. (2010) A novel double-coating approach for improved pH-triggered delivery to the ileo-colonic region of the gastrointestinal tract. European Journal of Pharmaceutics and Biopharmaceutics, 74 (2). pp. 311-315. 10.1016/j.ejpb.2009.11.008.

Liu, F. and Basit, A.W. (2010) A paradigm shift in enteric coating: achieving rapid release in the proximal small intestine of man. Journal of Controlled Release, 147 (2). pp. 242-245. 10.1016/j.jconrel.2010.07.105.

Fadda, H. M., Sousa, T., Carlsson, A. S., Abrahamsson, B., Williams, J. G., Kumar, D. and Basit, A.W. (2010) Drug Solubility in Luminal Fluids from Different Regions of the Small and Large Intestine of Humans. Molecular Pharmaceutics, 7 (5). pp. 1527-1532. 10.1021/mp100198q.

Alhnan, M.A., Cosi, D., Murdan, S. and Basit, A.W. (2010) Inhibiting the gastric burst release of drugs from enteric microparticles: the influence of drug molecular mass and solubility. Journal of Pharmaceutical Sciences, 99 (11). pp. 4576-83. 10.1002/jps.22174 .

Varum, F.J., Merchant, H.A. and Basit, A.W. (2010) Oral modified-release formulations in motion: The relationship between gastrointestinal transit and drug absorption. International Journal of Pharmaceutics, 395 (1-2). pp. 26-36. doi:10.1016/j.ijpharm.2010.04.046.

Fadda, H.M., Khanna, M., Santos, J.C., Osman, D., Gaisford, S. and Basit, A.W. (2010) The use of dynamic mechanical analysis (DMA) to evaluate plasticization of acrylic polymer films under simulated gastrointestinal conditions. European Journal of Pharmaceutics and Biopharmaceutics, 76 (3). p. 493. doi:10.1016/j.ejpb.2010.08.007.

McConnell, E.L., Macfarlane, C.B. and Basit, A.W. (2009) An observational study on the influence of solvent composition on the architecture of drug-layered pellets. International Journal of Pharmaceutics, 380 (1-2). pp. 67-71. 10.1016/j.ijpharm.2009.06.038.

Nilkumhang, S., Alhnan, M.A., McConnell, E.L. and Basit, A.W. (2009) Drug distribution in enteric microparticles. International Journal of Pharmaceutics, 379 (1). pp. 1-8. 10.1016/j.ijpharm.2009.05.066.

Nilkumhang, S. and Basit, A.W. (2009) The robustness and flexibility of an emulsion solvent evaporation method to prepare pH-responsive microparticles. International Journal of Pharmaceutics, 377 (1-2). pp. 135-141. 10.1016/j.ijpharm.2009.03.024.

Kendall, R.A., Alhnan, M.A., Nilkumhang, S., Murdan, S. and Basit, A.W. (2009) Fabrication and in vivo evaluation of highly pH responsive acrylic microparticles for targeted gastrointestinal delivery. European Journal of Pharmaceutical Sciences, 37 (3-4). pp. 284-290. 10.1016/j.ejps.2009.02.015.

Liu, F., Lizio, R., Schneider, V.J., Petereit, H.U., Blakey, P. and Basit, A.W. (2009) SEM/EDX and confocal microscopy analysis of novel and conventional enteric coated systems. International Journal of Pharmaceutics, 369 (1-2). pp. 72-78. 10.1016/j.ijpharm.2008.10.035.

McGirr, M., McAllister, M., Peters, E.E., Vickers, A.W., Parr, A.F. and Basit, A.W. (2009) The use of the Intelisite Companion device to deliver mucoadhesive polymers to the dog colon. European Journal of Pharmaceutical Sciences, 36 (4-5). pp. 386-391. 10.1016/j.ejps.2008.11.007.

Fadda, H.M., McConnell, E.L., Short, M.D. and Basit, A.W. (2009) Meal-induced acceleration of tablet transit through the human small intestine. Pharmaceutical Research, 26 (2). pp. 356-360. 10.1007/s11095-008-9749-2.

Liu, F., Lizio, R., Meier, C., Petereit, H.U., Blakey, P. and Basit, A.W. (2009) A novel concept in enteric coating: a double coating system providing rapid drug release in the proximal small intestine. Journal of Controlled Release, 133 (2). pp. 119-124. 10.1016/j.jconrel.2008.09.083.

Basit, A.W., Short, M.D. and McConnell, E.L. (2009) Microbiota-triggered colonic delivery: robustness of the polysaccharide approach in the fed state in man. Journal of Drug Targeting, 17 (1). pp. 64-71. 10.1080/10611860802455805.

McConnell, E.L., Macfarlane, C.B. and Basit, A.W. (2009) An observational study on the influence of solvent composition on the architecture of drug-layered pellets. International Journal of Pharmaceutics, 380 (1-2). pp. 67-71. doi:10.1016/j.ijpharm.2009.06.038.

McConnell, E.L., Liu, F. and Basit, A.W. (2009) Colonic treatments and targets: issues and opportunities. Journal of Drug Targeting, 17 . pp. 335-363. 10.1080/10611860902839502.

McConnell, E.L., Fadda, H.M. and Basit, A.W. (2009) Gut instincts: explorations in intestinal physiology and drug delivery. International Journal of Pharmaceutics, 364 (2). pp. 213-226. 10.1016/j.ijpharm.2008.05.012.

Fadda, H.M., Merchant, H.A., Arafat, B.T. and Basit, A.W. (2009) Physiological bicarbonate buffers: stabilisation and use as dissolution media for modified release systems. International Journal of Pharmaceutics, 382 (1-2). pp. 56-60. doi:10.1016/j.ijpharm.2009.08.003.

Ibekwe, V.C., Khela, M.K., Evams, D.F. and Basit, A.W. (2008) A new concept in colonic targeting: a combined pH-responsive and bacterially-triggered drug delivery technology. Alimentary Pharmacology and Therapeutics, 28 . pp. 911-916. 10.1111/j.1365-2036.2008.03810.x.

Sousa, T., Paterson, R., Moore, V., Carlsson, A., Abrahamsson, B. and Basit, A.W. (2008) The gastrointestinal microbiota as a site for the biotransformation of drugs. International Journal of Pharmaceutics, 363 (1-2). pp. 1-25. 10.1016/j.ijpharm.2008.07.009.

Mwesigwa, E., Basit, A.W. and Buckton, G. (2008) Moisture sorption and permeability characteristics of polymer films: implications for their use as barrier coatings for solid dose hydrolysable drug substances. Journal of Pharmaceutical Sciences, 97 (10). pp. 4433-4445. 10.1002/jps.21304.

McConnell, E.L., Short, M.D. and Basit, A.W. (2008) An in vivo comparison of intestinal pH and bacteria as physiological trigger mechanisms for colonic targeting in man. Journal of Controlled Release, 130 (2). pp. 154-160. 10.1016/j.jconrel.2008.05.022 .

McConnell, E.L., Murdan, S. and Basit, A.W. (2008) An investigation into the digestion of chitosan (non-cross-linked and cross-linked) by human colonic bacteria. Journal of Pharmaceutical Sciences, 97 (9). pp. 3820-3829. 10.1002/jps.21271.

Ibekwe, V.C., Fadda, H.M., McConnell, E.L., Khela, M.K., Evans, D.F. and Basit, A.W. (2008) Interplay between intestinal pH, transit time and feed status on the in vivo performance of pH responsive ileo-colonic release systems. Pharmaceutical Research, 25 (8). pp. 1828-1835. 10.1007/s11095-008-9580-9.

McConnell, E.L., Basit, A.W. and Murdan, S. (2008) Measurements of rat and mouse gastrointestinal pH, fluid and lymphoid tissue, and implications for in vivo experiements. Journal of Pharmacy and Pharmacology, 60 (1). pp. 63-70. 10.1211/jpp.60.1.0008.

Kendall, R.A., McConnell, E.L., Murdan, S. and Basit, A.W. (2008) A novel microparticle technology for tailored drug release in the gastrointestinal tract. In: Modified Release Drug Delivery Technology . 2nd ed. Drugs and the Pharmaceutical Sciences (183). Informa Healthcare, New York and London, pp. 261-268. ISBN 978-1420044355.

McConnell, E.L., Basit, A.W. and Murdan, S. (2008) Assessment of an enteric nanoparticle-in-microparticle protein delivery system using confocal microscopy. AAPS Journal, 10 (2). p. 2640.

McConnell, E.L., Basit, A.W. and Murdan, S. (2008) Colonic antigen administration induces significantly higher humoral levels of colonic and vaginal IgA and serum IgG compared to oral administration. Vaccine, 26 (5). pp. 639-646. 10.1016/j.vaccine.2007.11.071 .

McConnell, E.L., Sousa, L., Basit, A.W. and Murdan, S. (2008) Determination of fluid, pH and lymphoid tissue in the gastrointestinal tract of pigs. AAPS Journal, 10 (2). p. 2243.

Fadda, H.M., Mohamed, M.A. and Basit, A.W. (2008) Impairment of the in vitro drug release behaviour of oral modified release preparations in the presence of alcohol. International Journal of Pharmaceutics, 360 . pp. 171-176. 10.1016/j.ijpharm.2008.04.035.

Varum, F.J., McConnell, E.L., Sousa, J.J., Veiga, F. and Basit, A.W. (2008) Mucoadhesion and the gastrointestinal tract. Critical Reviews in Therapeutic Drug Carrier Systems, 25 (3). pp. 207-258.

Varum, F.0., Basit, A.W., Sousa, J.J. and Veiga, F. (2008) Mucoadhesion studies in the gastrointestinal tract to increase oral drug bioavailability. Brazilian Journal of Pharmaceutical Sciences, 44 . pp. 535-548. 10.1590/S1516-93322008000400002.

Ashiru, D.A., Patel, R. and Basit, A.W. (2008) Polyethylene Glycol 400 Enhances the Bioavailability of a BCS Class III Drug (Ranitidine) in Male Subjects but Not Females. Pharmaceutical Research, 25 (10). pp. 2327-2333. doi:10.1007/s11095-008-9635-y.

Ashiru, D.A., Patel, R. and Basit, A.W. (2008) Polyethylene glycol 400 enhances the bioavailability of a BCS class III drug (ranitidine) in male subjects but not females. Pharmaceutical Research, 25 (10). pp. 2327-33. 10.1007/s11095-008-9635-y .

McConnell, E.L. and Basit, A.W. (2008) Targeting the colon using COLAL: a novel bacteria-sensitive drug delivery system. In: Modified Release Drug Delivery Technology. Informa Healthcare, New York and London, pp. 354-358. ISBN 9781420044355.

Fadda, H.M., Hernandez, M.C., Margetson, D.N., McAllister, S.M., Basit, A.W., Brocchini, S. and Suarez, N. (2008) The molecular interactions that influence the plasticizer dependent dissolution of acrylic polymer films. Journal of Pharmaceutical Sciences, 97 (9). pp. 3957-3971. 10.1002/jps.21292.

Tuleu, C., Khela, M.K., Evans, D.F., Jones, B., Nagata, S. and Basit, A.W. (2007) A scintigraphic investigation of the disintegration behaviour of capsules in fasting subjects: a comparison of hypromellose capsules containing carrageenan as a gelling agent and standard gelatin capsules. European Journal of Pharmaceutical Sciences, 30 . pp. 251-255. 10.1016/j.ejps.2006.11.008.

McConnell, E.L., Basit, A.W. and Murdan, S. (2007) Chitosan and crosslinked chitosan for colonic specific drug delivery. In: AAPS Annual Meeting and Exposition, 11th-15th November 2007, San Diego, California, USA.

McConnell, E.L., Tutas, J., Mohamed, M.A., Banning, D. and Basit, A.W. (2007) Colonic drug delivery using amylose films: the role of aqueous ethylcellulose dispersions in controlling drug release. Cellulose, 14 (1). pp. 25-34. 10.1007/s10570-006-9078-8 .

McConnell, E.L., Basit, A.W. and Murdan, S. (2007) Quantification of lymphoid tissue in the rat and mouse gastrointestinal tract. In: AAPS Annual Meeting and Exposition, 11th-15th November 2007, San Diego, California, USA.

McConnell, E., Basit, A.W. and Murdan, S. (2007) The colon as a site for vaccination: preliminary studies in mice using a nanoparticle vaccine. In: AAPS Annual Meeting.

Ibekwe, V.C., Liu, F., Fadda, H.M., Khela, M.K., Evans, D.F., Parsons, G.E. and Basit, A.W. (2006) An investigation into the in vivo performance variability of pH responsive polymers for ileo-colonic drug delivery using gamma scintigraphy in humans. Journal of Pharmaceutical Sciences, 95 (12). pp. 2760-2766. 10.1002/jps.20742.

McConnell, E.L., Basit, A.W. and Murdan, S. (2006) An investigation into the digestibility of chitosan by human colonic bacteria. In: 33rd International Symposium of the Controlled Release Society, 22nd - 26th July 2006, Vienna, Austria.

Kendall, R.A., Murdan, S. and Basit, A.W. (2006) In vivo evaluation of pH-sensitive polymeric microparticles for site specific drug delivery to the small intestine and colon. In: 33rd International Symposium of the Controlled Release Society, 22nd - 26th July 2006, Vienna, Austria.

Schulze, J.D., Ashiru, D.A., Khela, M.K., Evans, D.F., Patel, R., Parsons, G.E., Coffin, M.D. and Basit, A.W. (2006) Impact of formulation excipients on human intestinal transit. Journal of Pharmacy and Pharmacology, 58 (6). pp. 821-825. 10.1211/jpp.58.6.0012.

Ibekwe, V.C., Fadda, H.M., Parsons, G.E. and Basit, A.W. (2006) A comparative in vitro assessment of the drug release performance of pH-responsive polymers for ileo-colonic delivery. International Journal of Pharmaceutics, 308 (1-2). pp. 52-60. 10.1016/j.ijpharm.2005.10.038.

McConnell, E., Basit, A.W. and Murdan, S. (2006) The colon as a target for vaccination: quantification of lymphoid tissue in mouse colon prior to vaccination. In: British Pharmaceutical Conference, 2006.

McConnell, E.L., Basit, A.W. and Murdan, S. (2006) The colon as a target for vaccination: quantification of lymphoid tissue in mouse colon prior to vaccination. Journal of Pharmacy and Pharmacology, 58 . A46-A46.

Mwesigwa, E., Buckton, G. and Basit, A.W. (2005) The hygroscopicity of moisture barrier film coatings. Drug Development and Industrial Pharmacy, 31 (10). pp. 959-968. 10.1080/03639040500306187.

Tuleu, C., Khela, M.K., Evans, D., Jones, B., Nagata, S. and Basit, A.W. (2005) Hypromellose capsules using carrageenan as gelling agent are bioequivalent to gelatin capsules in fed subjects. In: AAPS Annual Meeting, 6th-10th November 2005, Nashville, USA.

Kendall, R., Murdan, S. and Basit, A.W. (2005) Modified release microparticles for oral drug delivery. Drug Delivery Technology, 5 (8). pp. 76-80.

Kendall, R.A., Murdan, S. and Basit, A.W. (2005) A comparison of different microencapsulation techniques for the production of enteric microparticles from the acrylic polymer Eudragit 1100. In: AAPS Annual Meeting, 2005.

Kendall, R., Murdan, S. and Basit, A.W. (2005) Formulation, characterisation and evaluation of modified-release microparticles for oral drug delivery. In: Proceedings of the 32nd International Symposium of the Controlled Release Society on Bioactive Materials, 2005, Montreal, Canada.

School of Pharmacy (2005) Method of producing microparticles. WO 2005/070391.

Kendall, R., Murdan, S. and Basit, A.W. (2005) Novel modified release microparticles for oral delivery of drugs with different physicochemical properties. In: AAPS Annual Meeting, 2005, Nashville, USA.

Tuleu, C., Khela, M.K., Evans, D., Jones, B., Nagata, S. and Basit, A.W. (2004) A comparative scintigraphic assessment of the disintegration of HPMC and gelatin capsules in fasting subjects. In: AAPS Annual Meeting, 2004, Baltimore, USA.

Tuleu, C., Basit, A.W., Waddington , W.A., Ell, P.J. and Newton, J.M. (2002) Colonic delivery of 4-aminosalicylic acid using amylose-ethycellulose coated hydroxyproplymethyl cellulose capsules. Alimentary Pharmacology and Therapeutics, 16 . pp. 1771-1779. 10.1046/j.1365-2036.2002.01327.x.

Basit, A.W., Podczeck, F., Newton, J.M., Waddington , W.A., Ell, P.J. and Lacey, L.F. (2002) Influence of Polyethylene Glycol 400 on the Gastrointestinal Absorption of Ranitidine. Pharmaceutical Research, 19 (9). pp. 1368-1374. 10.1023/A:1020315228237 .

Basit, A.W., Newton, J.M., Short, M.D., Waddington , W.A., Ell, P.J. and Lacey, L.F. (2001) The Effect of Polyethylene Glycol 400 on Gastrointestinal Transit: Implications for the Formulation of Poorly-Water Soluble Drugs. Pharmaceutical Research, 18 (8). pp. 1146-1150. 10.1023/A:1010927026837 .

Siew, L.F., Basit, A.W. and Newton, J.M. (2000) The potential of organic-based amylose-ethylcellulose film coatings as oral colon-specific drug delivery systems. AAPS PharmSciTech, 1 (3). pp. 53-61. 10.1208/pt010322 .

This list was generated on Fri Oct 24 07:59:51 2014 BST.