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Number of items: 45.


Karu, K., Turton, J.A., Wang, Y. and Griffiths, W.J. (2011) Nano-liquid chromatography-tandem mass spectrometry analysis of oxysterols in brain: monitoring of cholesterol autoxidation. Chemistry and Physics of Lipids . 10.1016/j.chemphyslip.2011.04.011.


Brady, S., York, M., Scudamore, C., Williams, T., Griffiths, W.J. and Turton, J.A. (2010) Cardiac troponin I in isoproterenol-induced cardiac injury in the Hanover Wistar rat; studies on low dose levels and routes of administration. Toxicologic Pathology . 10.1177/0192623309357948.


Kim, C.E., Griffiths, W.J. and Taylor, P.W. (2009) Components derived from Pelargonium stimulate macrophage killing of Mycobacterium species. Journal of Applied Microbiology, 106 . pp. 1184-1193. 10.1111/j.1365-2672.2008.04085.x.

Smyth, R., Lane, C.S., Ashiq, R., Turton, J.A., Clarke, C.J., Dare, T.O., York, M.J., Griffiths, W.J. and Munday, M. (2009) Proteomic investigation of urinary markers of carbon-tetrachloride-induced hepatic fibrosis in the Hanover Wistar rat. Cell Biology and Toxicology, 25 (5). pp. 499-512. doi:10.1007/s10565-008-9104-8.


Narayanaswamy, M., Griffiths, W.J., Howard, P.W. and Thurston, D.E. (2008) An assay combining high-performance liquid chromatography and mass spectrometry to measure DNA interstrand cross-linking efficiency in oligonucleotides of varying sequences. Analytical Biochemistry, 374 (1). pp. 173-181. 10.1016/j.ab.2007.11.018.

Wang, Y.-W., Muneton, S., Sjövall, J., Jovanovic, J.N. and Griffiths, W.J. (2008) The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome. Journal of Proteome Research, 7 (4). pp. 1606-1614. 10.1021/pr7006076.


York, M., Scudamore, C., Brady, S., Chen, C., Wilson, S., Curtis, M., Evans, G., Griffiths, W.J., Whayman, M. and Williams, T. (2007) Characterization of troponin responses in isoproterenol-induced cardiac injury in the Hanover Wistar rat. Toxicologic Pathology, 35 (4). pp. 606-617. 10.1080/01926230701389316.

Wang, Y., Karu, K. and Griffiths, W.J. (2007) Analysis of neurosterols and neurosteroids by mass spectrometry. Biochimie, 89 (2). pp. 182-191. 10.1016/j.biochi.2006.10.008 .

Karu, K., Hornshaw, M., Woffendin, G., Bodin, K., Hamberg, M., Alvelius, G., Sjovall, J., Turton, J.A., Wang, Y. and Griffiths, W.J. (2007) Liquid chromatography-mass spectrometry utilising multi-stage fragmentation for the identification of oxysterols. Journal of Lipid Research, 48 . pp. 976-987. 10.1194/jlr.M600497-JLR200.


Wang, Y., Al-Gazzar, A., Seibert, C., Sharif, A., Lane, C.S. and Griffiths, W.J. (2006) Proteomic analysis of cytochromes P450: a mass spectrometry approach. Biochemical Society Transactions, 34 (6). pp. 1246-1251.

Rai, D.K., Landin, B., Alvelius, G. and Griffiths, W.J. (2006) Haemoglobin Sodertalje (beta118 Phe-->Val):a new mutation in human haemoglobin identified by electrospray ionisation mass spectrometry. Rapid Communications in Mass Spectrometry, 20 (22). pp. 3481-3482. 10.1002/rcm.2746.

Griffiths, W.J. (2006) Why steroidomics in brain? European Journal of Lipid Science and Technology, 108 . pp. 707-708. 10.1002/ejlt.200600162.

Wang, Y., Hornshaw, M., Alvelius, G., Bodin, K., Liu, S., Sjovall, J. and Griffiths, W.J. (2006) Matrix-assisted laser desorption/ionixation high-energy collision-induced dissociation of steroids: analysis of oxysterols in rat brain. Analytical Chemistry, 78 (1). pp. 164-173. 10.1021/ac051461b.

Khan, M.A., Wang, Y., Heidelberger, S., Alvelius, G., Liu, S., Sjovall, J. and Griffiths, W.J. (2006) Analysis of derivatised sterioids by matrix-assisted laser desorption/ionisation and post-source decay mass spectrometry. Steroids, 71 (1). pp. 42-53. 10.1016/j.steroids.2005.08.002.

Griffiths, W.J., Wang, Y., Alvelius, G., Liu, S., Bodin, K. and Sjovall, J. (2006) Analysis of oxysterols by electrospray tandem mass spectrometry. Journal of the American Society for Mass Spectrometry, 17 (3). pp. 341-362. 10.1016/j.jasms.2005.10.012.

Tjernberg, A., Markova, N., Griffiths, W.J. and Hallen, D. (2006) DMSO-related effects in protein characterization. Journal of Biomolecular Screening, 11 (2). pp. 131-137. 10.1177/1087057105284218.


Tollin, M., Bergsson, G., Kai-Larsen, Y., Lengqvist, J., Sjovall, J., Griffiths, W.J., Skuladottir, G.V., Haraldsson, A., Jornvall, H., Gudmundsson, G.H. and Agerberth, B. (2005) Vernix caseosa as a multi-component defence system based on polypeptides, lipids and their interactions. Cellular and Molecular Life Sciences, 62 (19-20). pp. 2390-2399. 10.1007/s00018-005-5260-7.

Lenqvist, J., Alvelius, G., Jornvall, H., Sjovall, J., Perlmann, T. and Griffiths, W.J. (2005) Electrospray mass spectrometry for the direct accurate mass measurement of ligands in complex with the retinoid X receptor alpha ligand binding domain. Journal of the American Society for Mass Spectrometry, 16 . pp. 1631-1640. 10.1016/j.jasms.2005.06.003.

Hosia, W., Griffiths, W.J. and Johansson, J. (2005) Hydrolysis of the amyloid beta-peptide (Abeta) 1-40 between Asp23-Val.24 produces non-aggregating fragments. An electrospray mass spectrometric study. Journal of Mass Spectrometry, 40 . pp. 142-145. 10.1002/jms.732.

Lenqvist, J., Mata de Urquiza, A., Perlmann, T., Sjovall, J. and Griffiths, W.J. (2005) Specificity of receptor-ligand interactions and their effect on dimerisation as observed by electrospray mass spectrometry: bile acids form stable adducts to the RXRalpha. Journal of Mass Spectrometry, 40 . pp. 1448-1461. 10.1002/jms.925.

Griffiths, W.J., Shackleton, C. and Sjovall, J. (2005) Steroid analysis. In: The Encyclopaedia of mass spectrometry Vol. 3. Biological applications; carbohydrates, nucleic acids and other biological compounds. Elsevier Ltd., Oxford, pp. 447-473.


Liere, P., Pianos, A., Eychenne, B., Cambourg, A., Liu, S., Griffiths, W.J., Schumacher, M., Sjovall, J. and Baulieu, E.-E. (2004) Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain. Journal of Lipid Research, 45 (12). pp. 2287-2302. 10.1194/jlr.M400244-JLR200.

Lane, C.S., Nisar, S., Griffiths, W.J., Fuller, B.J., Davidson, B.R., Hewes, J., Welham, K.J. and Patterson, L.H. (2004) Identification of cytochrome P450 enzymes in human colorectal metastases and the surrounding liver: a proteomic approach. European Journal of Cancer, 40 (14). pp. 2127-2134. 10.1016/j.ejca.2004.04.029.

Norberg, A., Griffiths, W.J., Hjelmqvist, L., Jornvall, H. and Rokaeus, A. (2004) Identification of variant forms of the neuroendocrine peptide galanin. Rapid Communications in Mass Spectrometry, 18 (14). pp. 1583-1591. 10.1002/rcm.1522.

Juntti-Berggren, L., Refai, E., Appelskog, I., Andersson, M., Imreh, G., Dekki, M., Uhles, S., Yu, L., Griffiths, W.J., Zaitsev, S., Leibiger, I., Yang, S.N., Olivecrona, G., Jornvall, H. and Berggren, P.O. (2004) Apolipoprotein C III promotes Ca2+ dependent beta-cell death in type 1 diabetes. Proceedings of the National Academy of the USA, 101 . pp. 10090-10094. 10.1073/pnas.0403551101.

Lenqvist, J., Svensson, R., Evergren, E., Morgenstern, R. and Griffiths, W.J. (2004) Observation of an intact noncovalent homotrimer of detergent-solubilized rat microsomal glutathione transferase-1 by electrospray mass spectrometry. Journal of Biological Chemistry, 279 (14). pp. 13311-13316. 10.1074/jbc.M310958200.

Nisar, S., Lane, C.S., Wilderspin, A.F., Welham, K.J., Griffiths, W.J. and Patterson, L.H. (2004) A proteomic approach to the identification of cytochrome P450 isoforms in male and female rat liver by nanoscale liquid chromatography-electrospray ionization-tandem mass spectrometry. Drug Metabolism and Disposition, 32 (4). pp. 382-386.

Rai, D.K., Green, B.N., Landin, B., Alvelius, G. and Griffiths, W.J. (2004) Accurate mass measurement and tandem mass spectrometry of intact globin chains identify the low proportion variant hemoglobin Lepore-Boston-Washington from the blood of a heterozygote. Journal of Mass Spectrometry, 39 . pp. 289-294. 10.1002/jms.581.

Griffiths, W.J. (2004) Derivatisation of peptides for analysis. In: The Encyclopaedia of mass spectrometry Vol. 2. Biological applications. Part A: Peptides and Proteins. Elsevier Ltd., Oxford, pp. 65-90. ISBN 0080438008.

Tjernberg, A., Carno, S., Oliv, F., Benkestock, K., Edlund, P-O., Griffiths, W.J. and Hallen, D. (2004) Determination of dissociation constants for protein-ligand complexes by electrospray ionization mass spectrometry. Analytical Chemistry, 76 . pp. 4325-4331. 10.1021/ac0497914.

Griffiths, W.J., Alvelius, G., Liu, S. and Sjovall, J. (2004) High-energy collision-induced dissociation of oxosteroids derivatised to Girard hydrazones. European Journal of Mass Spectrometry, 10 . pp. 63-88. 10.1255/ejms.625.

Lenqvist, J., De Urquiza, A.M., Bergman, A.C., Wilson, T.M., Sjovall, J., Perlmann, T. and Griffiths, W.J. (2004) Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid X receptor alpha ligand binding domain. Molecular and Cellular Proteomics, 3 (7). pp. 692-703. 10.1074/mcp.M400003-MCP200.

Wang, Y., Johansson, J., Agerberth, B., Jornvall, H. and Griffiths, W.J. (2004) The antimicrobial peptide LL-37 binds to the human plasma protein apolipoprotein A-I. Rapid Communications in Mass Spectrometry, 18 . pp. 588-589. 10.1002/rcm.1361.


Hjelmqvist, L., Norin, A., El-Ahmad, M., Griffiths, W.J. and Jornvall, H. (2003) Distinct but parallel evolutionary patterns between alcohol and aldehyde dehydrogenases: addition of fish/human betaine aldehyde dehydrogenase divergence. Cellular and Molecular Life Sciences, 60 (9). pp. 2009-2016. 10.1007/s00018-003-3287-1.

Palm, J.E., Weiland, M.E., Griffiths, W.J., Ljungstrom, I. and Svard, S.G. (2003) Identification of immunoreactive proteins during acute human giardiasis. Journal of Infectious Diseases, 187 (12). pp. 1849-1859.

Rai, D.K., Griffiths, W.J., Landin, B., Wild, B.J., Alvelius, G. and Green, B.N. (2003) Accurate mass measurement by electrospray ionization quadrupole mass spectrometry: detection of variants differing by <6 Da from normal in human hemoglobin heterozygotes. Analytical Chemistry, 75 (9). pp. 1978-1982. 10.1021/ac026228h.

Hedberg, J.J., Griffiths, W.J., Nilsson, S.J. and Hoog, J.O. (2003) Reduction of S-nitrosoglutathione by human alcohol dehydrogenase 3 is an irreversible reaction as analysed by electrospray mass spectrometry. European Journal of Biochemistry, 270 (6). pp. 1249-1256. 10.1046/j.1432-1033.2003.03486.x.

Hoog, J.O., Stromberg, P., Hedberg, J.J. and Griffiths, W.J. (2003) The mammalian alcohol dehydrogenases interact in several metabolic pathways. Chemico-Biological Interactions, 143-144 . pp. 175-181. 10.1016/S0009-2797(02)00225-9.

Liu, S., Griffiths, W.J. and Sjovall, J. (2003) Capillary liquid chromatography/electrospray mass spectrometry for analysis of steroid sulfates in biological samples. Analytical Chemistry, 75 . pp. 1022-1030. 10.1021/ac0262154.

Weiland, M.E., Palm, J.E., Griffiths, W.J., McCaffery, J.M. and Svard, S.G. (2003) Characterisation of alpha-1 giardin: an immunodominant Giardia lamblia annexin with glycosaminoglycan-binding activity. International Journal for Parasitology, 33 . pp. 1341-1351. 10.1016/S0020-7519(03)00201-7.

Griffiths, W.J., Liu, S., Alvelius, G. and Sjovall, J. (2003) Derivatisation for the characterisation of neutral oxosteroids by electrospray and matrix-assisted laser desorption/ionisation tandem mass spectrometry: the Girard P derivative. Rapid Communications in Mass Spectrometry, 17 . pp. 924-935. 10.1002/rcm.1002.

Abraham-Nordling, M., Gudmundsson, G.H., Grunewald, J., Agerberth, B. and Griffiths, W.J. (2003) Identification of a potent antibacterial factor isolated from bronchoalveolar lavage fluid: guanidine, N-[3-[(aminoiminomethyl)amino]propyl]-N-dodecyl-,a potential source of error in the analysis of antibacterial agents. Rapid Communications in Mass Spectrometry, 17 . pp. 183-191. 10.1002/rcm.891.

Liu, S., Sjovall, J. and Griffiths, W.J. (2003) Neurosteroids in rat brain: extraction, isolation and analysis by nanoscale liquid chromatography-electrospray mass spectrometry. Analytical Chemistry, 75 . pp. 5835-5846. 10.1021/ac0346297.

Liu, S., Griffiths, W.J. and Sjovall, J. (2003) On-column electrochemical reactions accompanying the electrospray process. Analytical Chemistry, 75 . pp. 1022-1030. 10.1021/ac026066p.

Griffiths, W.J. (2003) Tandem mass spectrometry in the study of fatty acids, bile acids, and steroids. Mass Spectrometry Reviews, 22 . pp. 81-152. 10.1002/mas.10046.

This list was generated on Thu May 28 23:13:15 2015 BST.