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Number of items: 23.

Haider, S.M., Autiero, I. and Neidle, S. (2011) Surface area accessibility and the preferred topology of telomeric DNA quadruplex-ligand complexes. Biochimie, 93 (8). pp. 1275-1279. 10.1016/j.biochi.2011.05.014.

Haider, S.M., Neidle, S. and Parkinson, G.N. (2011) A structural analysis of G-quadruplex/ligand interactions. Biochimie, 93 (8). pp. 1239-1251. 10.1016/j.biochi.2011.05.012.

Haider, S.M., Joseph, C.G., Neidle, S., Fierke, C.A. and Fuchter, M.J. (2011) On the function of the internal cavity of histone deacetylase protein 8: R37 is a crucial residue for catalysis. Bioorganic & Medicinal Chemistry Letters, 21 (7). pp. 2129-2132. 10.1016/j.bmcl.2011.01.128.

Petraccone, L., Fotticchia, I., Cummaro, A., Pagano, B., Ginnari-Satriani, L., Haider, S.M., Randazzo, A., Novellino, E., Neidle, S. and Giancola, C. (2011) The triazatruxene derivative azatrux binds to the parallel form of the human telomeric G-quadruplex under molecular crowding conditions: Biophysical and molecular modeling studies. Biochimie, 93 (8). pp. 1318-1327. 10.1016/j.biochi.2011.05.017.

Haider, S.M., Patel, J., Poojari, C. and Neidle, S. (2010) Molecular modeling on inhibitor complexes and active-site dynamics of cytochrome P450 C17, a target for prostate cancer therapy. Journal of Molecular Biology, 400 (5). pp. 1078-1098. 10.1016/j.jmb.2010.05.069 .

Moses, J., Ritson, D., Zhang, F., Lombardo, C.M., Haider, S.M., Oldham, N. and Neidle, S. (2010) A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands. Organic and Biomolecular Chemistry, 8 (13). pp. 2926-2930. 10.1039/c005055e.

Collie, G.W., Haider, S.M., Neidle, S. and Parkinson, G.N. (2010) A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex. Nucleic Acids Research . 10.1093/nar/gkq259 .

Zinzalla, G., Haque, M.R., Basu, B Piku, Anderson, J., Kaye, S.L., Haider, S.M., Hasan, F., Antonow, D., Essex, S., Rahman, K.M., Palmer, J., Morgenstern, D., Wilderspin, A.F., Neidle, S. and Thurston, D.E. (2010) A novel small-molecule inhibitor of IL-6 signalling. Bioorganic & Medicinal Chemistry Letters, 20 (23). pp. 7029-32. 10.1016/j.bmcl.2010.09.117.

Sparapani, S., Bellini, S., Gunaratnam, M., Haider, S.M., Andreani, A., Rambaldi, M., Locatelli, A., Morigi, R., Granaiola, M., Varoli, L., Burnelli, S., Leoni, A. and Neidle, S. (2010) Bis-guanylhydrazone diimidazo[1,2-a:1,2-c]pyrimidine as a novel and specific G-quadruplex binding motif. Chemical Communications, 46 (31). pp. 5680-5682. 10.1039/c0cc00020e.

Haider, S.M. and Neidle, S. (2010) Molecular modeling and simulation of G-quadruplexes and quadruplex-ligand complexes. In: G-Quadruplex DNA: Methods and Protocols. Methods in molecular biology (608). Humana Press, NJ, USA, pp. 17-37. ISBN 978-1588299505 . 10.1007/978-1-59745-363-9_2.

Sparapani, S., Haider, S.M., Doria, F., Gunaratnam, M. and Neidle, S. (2010) Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes. Journal of the American Chemical Society, 132 (35). pp. 12263-12272. 10.1021/ja1003944.

Lombardo, C.M., Martínez, I.S., Haider, S.M., Gabelica, V., De Pauw, E., Moses, J.E. and Neidle, S. (2010) Structure-based design of selective high-affinity telomeric quadruplex-binding ligands. Chemical Communications, 46 (48). pp. 9116-9118. 10.1039/C0CC02917C.

Haider, S.M. and Neidle, S. (2009) A molecular model for drug binding to tandem repeats of telomeric G-quadruplexes. Biochemical Society Transactions, 37 (3). pp. 583-588. 10.1042/BST0370583.

Rahman, K.M., Reszka, A.P., Gunaratnam, M., Haider, S.M., Howard, P.W., Fox, K.R., Neidle, S. and Thurston, D.E. (2009) Biaryl polyamides as a new class of DNA quadruplex-binding ligands. Chemical Communications, 27 . pp. 4097-4099. 10.1039/b902359c.

Tai, K., Haider, S.M., Grottesi, A. and Sansom, M.S.P. (2009) Ion channel gates: comparative analysis of energy barriers. European Biophysics Journal, 38 (4). pp. 347-354. doi:10.1007/s00249-008-0377-x.

Collie, G.W., Reszka, A.P., Haider, S.M., Gabelica, V., Parkinson, G.N. and Neidle, S. (2009) Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes. Chemical Communications, 48 . pp. 7482-7484. 10.1039/b901889a.

Gunaratnam, M., Swank, S., Haider, S.M., Galesa, K., Reszka, A.P., Beltran, M., Cuenca, F., Fletcher, J.A. and Neidle, S. (2009) Targeting human gastrointestinal stromal tumour cells with a quadruplex-binding small molecule. Journal of Medicinal Chemistry, 52 (12). pp. 3774-3783. 10.1021/jm900424a.

Haider, S.M., Parkinson, G.N. and Neidle, S. (2008) Molecular dynamics and principal components analysis of human telomeric quadruplex multimers. Biophysical Journal, 95 (1). pp. 296-311. 10.1529/biophysj.107.120501.

Cuenca, F., Greciano, O., Gunaratnam, M., Haider, S.M., Munnur, D., Nanjunda, R., Wilson, W.D. and Neidle, S. (2008) Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands. Bioorganic and Medicinal Chemistry Letters, 18 (5). pp. 1668-1673. 10.1016/j.bmcl.2008.01.050.

Moorhouse, A.D., Gunaratnam, M., Haider, S.M., Munnur, D., Neidle, S. and Moses, J.E. (2008) Targeting telomerase and telomeres: a click chemistry approach towards highly selective G-quadruplex ligands. Molecular Biosystems, 4 (6). pp. 629-642. 10.1039/b801822g.

Todd, A.K., Haider, S.M., Parkinson, G.N. and Neidle, S. (2007) Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter. Nucleic Acids Research, 35 (17). pp. 5799-5808. 10.1093/nar/gkm609.

Harrison, R.J., Reszka, A.P., Haider, S.M., Romagnoli, B., Morrell, J., Read, M.A., Gowan, S.M., Incles, C.M., Kelland, L.R. and Neidle, S. (2004) Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding. Bioorganic and Medicinal Chemistry Letters, 14 (23). pp. 5845-5849. 10.1016/j.bmcl.2004.09.037.

Haider, S.M., Parkinson, G.N. and Neidle, S. (2003) Structure of a G-quadruplex–Ligand Complex. Journal of Molecular Biology, 326 (1). pp. 117-125. 10.1016/S0022-2836(02)01354-2.

This list was generated on Sun Apr 20 21:53:01 2014 BST.