Browse by Person

Up a level
Export as [feed] RSS 2.0 [feed] RSS 1.0 [feed] Atom
Group by: Item Type | Date | No Grouping
Number of items: 103.

Article

Patrizi, A., Viltono, L., Frola, E., Harvey, K., Harvey, R.J. and Sassoè-Pognetto, M. (2012) Selective localization of collybistin at a subset of inhibitory synapses in brain circuits. Journal of Comparative Neurology, 520 (1). pp. 130-141. 10.1002/cne.22702.

Gill, J.L., Tsai, K.L., Krey, C., Noorai, R.E., Vanbellinghen, J-F., Garosi, L., Shelton, G.D., Clark, L.A. and Harvey, R.J. (2012) A canine BCAN microdeletion associated with episodic falling syndrome. Neurobiology of Disease, 45 (1). pp. 130-136. 10.1016/j.nbd.2011.07.014.

James, V.M., Gill, J.L., Topf, M. and Harvey, R.J. (2012) Molecular mechanisms of glycine transporter GlyT2 mutations in startle disease. Biological Chemistry, 393 (4). pp. 283-289. 10.1515/bc-2011-232.

Tretter, V., Kerschner, B., Milenkovic, I., Ramsden, S.L., Ramerstorfer, J., Saiepour, L., Maric, H-M., Moss, S.J., Schindelin, H., Harvey, R.J., Sieghart, W. and Harvey, K. (2011) Molecular basis of the GABAA receptor {alpha}3 subunit interaction with gephyrin. Journal of Biological Chemistry . 10.1074/jbc.M111.291336 .

Gill, J.L., Capper, D., Vanbellinghen, J-F., Chung, S-K., Higgins, R.J., Rees, M.I., Shelton, G.D. and Harvey, R.J. (2011) Startle disease in Irish wolfhounds associated with a microdeletion in the glycine transporter GlyT2 gene. Neurobiology of Disease, 43 (1). pp. 184-189. 10.1016/j.nbd.2011.03.010.

Vanhaesebrouck, A.E., Shelton, G.D., Garosi, L., Harcourt-Brown, T.R., Couturier, J., Behr, S., Harvey, R.J., Jeffery, N.D., Matiasek, K., Blakemore, W.F. and Granger, N. (2011) A Novel Movement Disorder in Related Male Labrador Retrievers Characterized by Extreme Generalized Muscular Stiffness. Journal of Veterinary Internal Medicine, 25 (5). pp. 1089-1096. 10.1111/j.1939-1676.2011.0757.x.

Chiou, T-T., Bonhomme, B., Jin, H., Miralles, C.P., Xiao, H., Fu, Z., Harvey, R.J., Harvey, K., Vicini, S. and De Blas, A.L. (2011) Differential regulation of the postsynaptic clustering of γ-aminobutyric acid type A (GABAA) receptors by collybistin isoforms. Journal of Biological Chemistry, 286 (25). pp. 22456-22468. 10.1074/jbc.M111.236190.

Ogino, K., Ramsden, S.L., Keib, N., Schwarz, G., Harvey, R.J. and Hirata, H. (2011) Duplicated gephyrin genes showing distinct tissue distribution and alternative splicing patterns mediate molybdenum cofactor biosynthesis, glycine receptor clustering, and escape behavior in zebrafish. Journal of Biological Chemistry, 286 (1). pp. 806-817. 10.1074/jbc.M110.125500 .

Gill, J.L., James, V.M., Carta, E., Harris, D., Topf, M., Scholes, S.F.E., Hateley, G. and Harvey, R.J. (2011) Identification of congenital muscular dystonia 2 associated with an inherited GlyT2 defect in Belgian Blue cattle from the United Kingdom. Animal Genetics . 10.1111/j.1365-2052.2011.02255.x.

Deas, E., Plun-Favreau, H., Gandhi, S., Desmond, H., Kjaer, S., Loh, S.H.Y., Renton, A.E.M., Harvey, R.J., Whitworth, A.J., Martins, L.M., Abramov, A.Y. and Wood, N.W. (2011) PINK1 cleavage at position A103 by the mitochondrial protease PARL. Human Molecular Genetics, 20 (5). pp. 867-879. 10.1093/hmg/ddq526.

Patrizi, A., Viltono, L., Frola, E., Harvey, K., Harvey, R.J. and Sassoè-Pognetto, M. (2011) Selective localization of collybistin at a subset of inhibitory synapses in brain circuits. Journal of Comparative Neurology . 10.1002/cne.22702.

Manzke, T., Niebert, M., Koch, U.R., Caley, A., Vogelgesang, S., Bischoff, A-M., Hülsmann, S., Ponimaskin, E., Müller, U., Smart, T.G., Harvey, R.J. and Richter, D.W. (2011) Serotonin receptor 1A-modulated dephosphorylation of glycine receptor α3: A new molecular mechanism of breathing control for compensation of opioid-induced respiratory depression without loss of analgesia. [Die von Serotoninrezeptor 1A modulierte Dephosphorylierung des Glyzinrezeptors α3]. Schmerz, 25 (3). pp. 272-281. 10.1007/s00482-011-1044-1.

Fukaya, M., Kamata, A., Hara, Y., Tamaki, H., Katsumata, O., Ito, N., Takeda, S., Hata, Y., Suzuki, T., Watanabe, M., Harvey, R.J. and Sakagami, H. (2011) SynArfGEF is a guanine nucleotide exchange factor for Arf6 and localizes preferentially at post-synaptic specializations of inhibitory synapses. Journal of Neurochemistry, 116 (6). pp. 1122-1137. 10.1111/j.1471-4159.2010.07167.x.

Kriebel, M., Metzger, J., Trinks, S., Chugh, D., Harvey, R.J., Harvey, K. and Volkmer, H. (2011) The cell adhesion molecule neurofascin stabilizes axo-axonic GABAergic terminals at the axon initial segment. Journal of Biological Chemistry, 286 (27). pp. 24385-24393. 10.1074/jbc.M110.212191 .

Kumar, R.A., Pilz, D.T., Babatz, T.D., Cushion, T.D., Harvey, K., Topf, M., Yates, L., Robb, S., Uyanik, G., Mancini, G.M.S., Rees, M.I., Harvey, R.J. and Dobyns, W.B. (2010) TUBA1A mutations cause wide spectrum lissencephaly (smooth brain) and suggest that multiple neuronal migration pathways converge on alpha tubulins. Human Molecular Genetics, 19 (14). pp. 2817-2827. 10.1093/hmg/ddq182 .

Shoubridge, C., Tarpey, P.S., Abidi, F., Ramsden, S.L., Rujirabanjerd, S., Murphy, J.A., Boyle, J., Shaw, M., Gardner, A., Proos, A., Puusepp, H., Raymond, F.L., Schwartz, C.E., Stevenson, R.E., Turner, G., Field, M., Walikonis, R.S., Harvey, R.J., Hackett, A., Futreal, P.A., Stratton, M.R. and Gecz, J. (2010) Mutations in the guanine nucleotide exchange factor gene IQSEC2 cause nonsyndromic intellectual disability. Nature Genetics, 42 . pp. 486-488. 10.1038/ng.588.

Davies, J.S., Chung, S-K., Thomas, R.H., Robinson, A., Hammond, C.L., Mullins, J.G., Carta, E., Pearce, B.R., Harvey, K., Harvey, R.J. and Rees, M.I. (2010) The glycinergic system in human startle disease: a genetic screening approach. Frontiers in Molecular Neuroscience, 3 . p. 8. 10.3389/fnmol.2010.00008.

Melzer, N., Villman, C., Becker, K., Harvey, K., Harvey, R.J., Vogel, N., Kluck, C.J., Kneussel, M. and Becker, C.M. (2010) Multifunctional basic motif in the glycine receptor intracellular domain induces subunit-specific sorting. Journal of Biological Chemistry, 285 (6). pp. 3730-3739. 10.1074/jbc.M109.030460 .

Thomas, R.H., Stephenson, J.B.P., Harvey, R.J. and Rees, M.I. (2010) Hyperekplexia: stiffness, startle and syncope. Journal of Pediatric Neurology, 8 (1). pp. 11-14. 10.3233/JPN-2010-0359.

Hirata, H., Carta, E., Yamanaka, I., Harvey, R.J. and Kuwada, J.Y. (2010) Defective glycinergic synaptic transmission in zebrafish motility mutants. Frontiers in Molecular Neuroscience, 8 (2). p. 26. 10.3389/neuro.02.026.2009.

Saiepour, L., Fuchs, C., Patrizi, A., Sassoe-Pognetto, M., Harvey, R.J. and Harvey, K. (2010) Complex Role of Collybistin and Gephyrin in GABAA Receptor Clustering. Journal of Biological Chemistry, 285 (38). pp. 29623-29631. 10.1074/jbc.M110.121368.

Harvey, R.J. and Rigo, J.M. (2010) Glycinergic transmission: physiological, developmental and pathological implications. Frontiers in Molecular Neuroscience, 3 . p. 115. 10.3389/fnmol.2010.00115 .

Chung, S-K., Vanbellinghen, J-F., Mullins, J.G., Robinson, A., Hantke, J., Hammond, C.L., Gilbert, D.F., Freilinger, M., Ryan, M., Kruer, M.C., Masri, A., Gurses, C., Ferrie, C., Harvey, K., Shiang, R., Christodoulou, J., Andermann, F., Andermann, E., Thomas, R.H., Harvey, R.J., Lynch, J.W. and Rees, M.I. (2010) Pathophysiological mechanisms of dominant and recessive GLRA1 mutations in hyperekplexia. Journal of Neuroscience, 30 (28). pp. 9612-9620. 10.1523/JNEUROSCI.1763-10.2010.

Manzke, T., Niebert, M., Koch, U.R., Caley, A., Vogelgesang, S., Hülsmann, S., Ponimaskin, E., Müller, U., Smart, T.G., Harvey, R.J. and Richter, D.W. (2010) Serotonin receptor 1A–modulated phosphorylation of glycine receptor α3 controls breathing in mice. Journal of Clinical Investigation, 120 (11). pp. 4118-4128. 10.1172/JCI43029.

Shoubridge, C., Walikonis, R.S., Gécz, J. and Harvey, R.J. (2010) Subtle functional defects in the Arf-specific guanine nucleotide exchange factor IQSEC2 cause non-syndromic X-linked intellectual disability. Small GTPases, 1 (2). pp. 98-103. 10.4161/sgtp.1.2.13285.

Harvey, V.L., Caley, A., Mueller, U.C., Harvey, R.J. and Dickenson, A.H. (2009) A selective role for alpha3 subunit glycine receptors in inflammatory pain. Frontiers in Molecular Neuroscience, 2 (14). 10.3389/neuro.02.014.2009.

Poulopoulos, A., Aramuni, G., Meyer, G., Soykan, T., Hoon, M., Papadopoulos, T., Zhang, M., Paarmann, I., Fuchs, C., Harvey, K., Jedlicka, P., Schwarzacher, S.W., Betz, H., Harvey, R.J., Brose, N., Zhang, W. and Varoqueaux, F. (2009) Neuroligin 2 drives postsynaptic assembly at perisomatic inhibitory synapses through gephyrin and collybistin. Neuron, 63 (5). pp. 628-642. 10.1016/j.neuron.2009.08.023.

den Eynden, J.V., Ali, S.S., Horwood, N., Carman, S., Brone, B., Hellings, N., Steels, P., Harvey, R.J. and Rigo, J.M. (2009) Glycine and glycine receptor signalling in non-neuronal cells. Frontiers in Molecular Neuroscience, 2 (9). 10.3389/neuro.02.009.2009.

Kalscheuer, V.M., Musante, L., Fang, C., Hoffmann, K., Fuchs, C., Carta, E., Deas, E., Venkateswarlu, K., Menzel, C., Ullmann, R., Tommerup, N., Dalpra, L., Tzschach, A., Selicorni, A., Luescher, B., Ropers, H.H., Harvey, K. and Harvey, R.J. (2009) A balanced chromosomal translocation disrupting ARHGEF9 is associated with epilepsy, anxiety, aggression and mental retardation. Human Mutation, 30 (1). pp. 61-68. 10.1002/humu.20814.

Chen, X., Cromer, B., Webb, T.I., Hantke, J. and Harvey, R.J. (2009) Dihydropyridine inhibition of the glycine receptor: subunit selectivity and a molecular determinant of inhibition. Neuropharmacology, 56 (1). pp. 318-327. 10.1016/j.neuropharm.2008.07.001.

Waessle, H., Heinze, L., Ivanova, E., Majumdar, S., Weiss, J. and Harvey, R.J. (2009) Glycinergic transmission in the mammalian retina. Frontiers in Molecular Neuroscience, 2 (6). 10.3389/neuro.02.006.2009.

Rajalu, M., Muller, U., Caley, A., Harvey, R.J. and Poisbeau, P. (2009) Plasticity of synaptic inhibition in mouse spinal cord lamina II neurons during early postnatal development and after inactivation. European Journal of Neuroscience, 30 . pp. 2284-2292. 10.1111/j.1460-9568.2009.07018.x.

Yang, Z., Aubrey, K.R., Alroy, I., Harvey, R.J., Vandenberg, R.J. and Lynch, J.W. (2008) Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine. Biochemical Pharmacology, 76 (8). pp. 1014-1023. 10.1016/j.bcp.2008.07.037.

Harvey, R.J., Topf, M., Harvey, K. and Rees, M.I. (2008) The genetics of hyperekplexia: more than startle! Trends in Genetics, 24 (9). pp. 439-447. 10.1016/j.tig.2008.06.005.

Charlier, C., Coppieters, W., Rollin, F., Desmecht, D., Agerholm, J.S., Cambisano, N., Carta, E., Dardano, S., Dive, M., Fasquelle, C., Frennet, J-C., Hanset, R., Hubin, X., Jorgensen, C., Karim, L., Kent, M., Harvey, K., Pearce, B.R., Simon, P., Tama, N., Nie, H., Vandeputte, S., Lien, S., Longeri, M., Fredholm, M., Harvey, R.J. and Georges, M. (2008) Highly effective SNP-based association mapping and management of recessive defects in livestock. Nature Genetics, 40 . pp. 449-454. 10.1038/ng.96.

Harvey, R.J., Carta, E., Pearce, B.R., Chung, S-K., Supplisson, S., Rees, M.I. and Harvey, K. (2008) A critical role for glycine transporters in hyperexcitability disorders. Frontiers in Molecular Neuroscience, 1 (1). 10.3389/neuro.02.001.2008.

Harvey, R.J., Chinchetru, M.A. and Darlison, M.G. (2008) Alternative Splicing of a 51-Nucleotide Exon that Encodes a Putative Protein Kinase C Phosphorylation Site Generates Two Forms of the Chicken γ-Aminobutyric AcidAReceptor β2 Subunit. Journal of Neurochemistry, 62 (1). pp. 10-16. 10.1046/j.1471-4159.1994.62010010.x.

Fritschy, J.-M., Harvey, R.J. and Schwarz, G. (2008) Gephyrin: where do we stand, where do we go? Trends in Neurosciences, 31 (5). pp. 257-264. 10.1016/j.tins.2008.02.006.

Harvey, R.J., Schmitt, B., Hermans-Borgmeyer, I., Gundelfinger, E.D., Betz, H. and Darlison, M.G. (2008) Sequence of a Drosophila Ligand-Gated Ion-Channel Polypeptide with an Unusual Amino-Terminal Extracellular Domain. Journal of Neurochemistry, 62 (6). pp. 2480-2483. 10.1046/j.1471-4159.1994.62062480.x.

Poirier, K., Keays, D.A., Francis, F., Saillour, Y., Bahi, N., Manouvrier, S., Fallet-Bianco, C., Pasquier, L., Toutain, A., Tuy, F.P., Bienvenu, T., Joriot, S., Odent, S., Ville, D., Desguerre, I., Goldenberg, A., Moutard, M.L., Fryns, J.P., van Esch, H., Harvey, R.J., Siebold, C., Flint, J., Beldjord, C. and Chelly, J. (2007) Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A). Human Mutation, 28 (11). pp. 1055-1064. 10.1002/humu.20572.

Plun-Favreau, H., Klupsch, K., Moisoi, N., Gandhi, S., Kjaer, S., Frith, D., Harvey, K., Deas, E., Harvey, R.J., McDonald, N., Wood, N.W., Martins, L.M. and Downward, J. (2007) The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nature Cell Biology, 9 (11). pp. 1243-1252. 10.1038/ncb1644.

Cromer, B.A., Yang, Z., Harvey, R.J., Parker, M.W. and Lynch, J.W. (2007) A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. Journal of Neurochemistry, 103 (2). pp. 580-589. 10.1111/j.1471-4159.2007.04850.x.

Papadopoulos, T., Korte, M., Eulenburg, V., Kubota, H., Retiounskaia, M., Harvey, R.J., Harvey, K., O'Sullivan, G.A., Laube, B., Hulsmann, S., Geiger, J.R. and Betz, H. (2007) Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice. EMBO Journal, 26 (17). pp. 3888-3899. 10.1038/sj.emboj.7601819.

Khodiyar, V.K., Maltais, L.J., Sneddon, K.M., Smith, J.R., Shimoyama, M., Cabral, F., Dumontet, C., Dutcher, S.K., Harvey, R.J., Lafanechere, L., Murray, J.M., Nogales, E., Piquemal, D., Stanchi, F., Povey, S. and Lovering, R.C. (2007) A revised nomenclature for the human and rodent α-tubulin gene family. Genomics, 90 (2). pp. 285-289. 10.1016/j.ygeno.2007.04.008 .

Heinze, L., Harvey, R.J., Haverkamp, S. and Wassle, H. (2007) Diversity of glycine receptors in the mouse retina: localization of the alpha4 subunit. Journal of Comparative Neurology, 500 (4). pp. 693-707. 10.1002/cne.21201.

Keays, D.A., Tian, G., Poirier, K., Huang, G.J., Siebold, C., Cleak, J., Oliver, P.L., Fray, M., Harvey, R.J., Molnar, Z., Pinon, M.C., Dear , N., Valdar, W., Brown, S.D., Davies, K.E., Rawlins, J.N., Cowan, N.J., Nolan, P., Chelly, J. and Flint, J. (2007) Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans. Cell, 128 (1). pp. 45-57. 10.1016/j.cell.2006.12.017 .

Hosl, K., Reinold, H., Harvey, R.J., Muller, U., Narumiya, S. and Zeilhofer, H.U. (2006) Spinal prostaglandin E receptors of the EP2 subtype and the glycine receptor alpha3 subunit, which mediate central inflammatory hyperalgesia, do not contribute to pain after peripheral nerve injury or formalin injection. Pain, 126 (1-3). pp. 46-53. 10.1016/j.pain.2006.06.011 .

Abou-Sleiman, P.M., Muqit, M.M.K., McDonald, N.Q., Gandhi, S., Healy, D.G., Harvey, K., Harvey, R.J., Bhatia, K., Quinn, N., Lees, A.J., Latchman, D.S. and Wood, N.W. (2006) A heterozygous effect for PINK1 mutations in Parkinson's disease; low frequency low penetrance? Annals of Neurology, 60 (4). pp. 414-419. 10.1002/ana.20960.

Rees, M.I., Harvey, K., Chung, S-K., Duguid, I.C., Thomas, P., Beatty, S., Graham, G., Armstrong, L., Shiang, R., Abbott, K.J., Zuberi, S., Stephenson, S., Owen, M.J., Tijssen, M.A.J., van den Maagdenberg, A.M.J.M., Smart, T.G., Supplisson, S. and Harvey, R.J. (2006) Mutations in the human GlyT2 gene define a presynaptic component of human startle disease. Nature Genetics, 38 . pp. 801-806. 10.1038/ng1814.

Muqit, M.M.K., Abou-Sleiman, P.M., Saurin, A.T., Harvey, K., Gandhi, S., Deas, E., Eaton, S., Payne Smith, M.D., Venner, K., Matilla, A., Healy, D.G., Gilks, W.P., Lees, A.J., Holton, J., Revesz, T., Parker, P.J., Harvey, R.J., Wood, N.W. and Latchman, D.S. (2006) Altered cleavage and localisation of PINK1 to aggresomes in the presence of proteasomal stress. Journal of Neurochemistry, 98 . pp. 156-159. 10.1111/j.1471-4159.2006.03845.x.

Greggio, E., Jain, S., Kingsbury, A.E., Bandopadhyay, R., Kaganovich, A., Lewis, P., van der Brug, M.P., Beilina, A., Blackinton, J., Thomas, K.J., Ahmad, R., Miller, D.W., Lees, A., Harvey, R.J., Harvey, K. and Cookson, M.R. (2006) Kinase activity is required for dominant effects of mutant dardarin. Neurobiology of Disease, 23 . pp. 329-341. 10.1016/j.nbd.2006.04.001 .

Rees, M.I., Harvey, K., Pearce, B.R., Chung, S-K., Duguid, I.C., Thomas, P., Beatty, S., Graham, G.E., Armstrong, L., Shiang, R., Abbott, K.J., Zuberi, S.M., Stephenson, J.B.P., Owen, M.J., Tijssen, M.A.J., van den Maagdenberg, A.M.J.M., Smart, T.G., Supplisson, S. and Harvey, R.J. (2006) Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease. Nature Genetics, 38 (7). pp. 801-806. 10.1038/ng1814.

Miller, P.S., Beato, M., Harvey, R.J. and Smart, T.G. (2005) Molecular determinants of glycine receptor alpha beta subunit sensitivities to Zn2+ inhibition. Journal of Physiology, 566 . pp. 657-670.

Meier, J.C., Henneberger, C., Melnick, I., Racca, C., Harvey, R.J., Heinemann, U., Schmeiden, V. and Grantyn, R. (2005) RNA editing produces glycine receptor alpha3P185L, resulting in high agonist potency. Nature Neuroscience, 8 . pp. 736-744. 10.1038/nn1467.

Bandopadhyay, R., Kingsbury, A.E., Muqit, M.M.K., Harvey, K., Reid, A.R., Engelender, S., Schlossmacher, M.G., Wood, N.W., Latchman, D.S., Harvey, R.J. and Lees, A.J. (2005) Synphilin-1 and Parkin show overlapping distribution patterns in human brain and form aggresomes in response to proteasomal inhibition. Neurobiology of Disease, 20 . pp. 401-411. 10.1016/j.nbd.2005.03.021.

Harvey, K., Duguid, I.C., Alldred, M.J., Beatty, S.E., Ward, H., Keep, N.H., Lingenfelter, S.E., Pearce, B.R., Lundgren, J., Owen, M.J., Smart, T.G., Luscher, B., Rees, M.I. and Harvey, R.J. (2004) The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering. Journal of Neuroscience, 24 (25). pp. 5816-5826. 10.1523/JNEUROSCI.1184-04.2004.

Miller, P.S., Harvey, R.J. and Smart, T.G. (2004) Differential agonist sensitivity of glycine receptor alpha2 subunit splice variants. British Journal of Pharmacology, 143 . pp. 19-26. 10.1038/sj.bjp.0705875.

Haverkamp, S., Muller, U., Zeilhofer, H.U., Harvey, R.J. and Wassle, H. (2004) Diversity of glycine receptors in the mouse retina: localization of the alpha2 subunit. Journal of Comparative Neurology, 477 . pp. 399-411. 10.1002/cne.20267.

Gaitatzis, A., Kartsounis, L.D., Gacinovic, S., Costa, D.C., Harvey, K., Harvey, R.J. and Silva, R.N. (2004) Frontal lobe dysfunction in sporadic hyperekplexia - case study and literature review. Journal of Neurology, 251 . pp. 91-98. 10.1007/s00415-004-0288-4.

Harvey, R.J., Depner, U.B., Wassle, H., Ahmadi, S., Heindl, C., Reinold, H., Smart, T.G., Harvey, K., Schutz, B., Abo-Salem, O.M., Zimmer, A., Poisbeau, P., Welzl, H., Wolfer, D.P., Betz, H., Zeilhofer, H.U. and Muller, U. (2004) GlyR alpha3:an essential target for spinal PGE2-mediated inflammatory pain sensitization. Science, 304 . pp. 884-887. 10.1126/science.1094925.

Valente, E.M., Abou-Sleiman, P.M., Caputo, V., Muqit, M.M.K., Harvey, K., Gispert, S., Ali, Z., Del Turco, D., Bentivoglio, A.R., Healy, D.G., Albanese, A., Nussbaum, R., Gonzalez-Maldonado, R., Deller, T., Salvi, S., Cortelli, P., Gilks, W.P., Latchman, D.S., Harvey, R.J., Dallapiccola, B., Auburger, G. and Wood, N.W. (2004) Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science, 304 . 1158 -1160. 10.1126/science.1096284.

Haverkamp, S., Muller, U., Harvey, K., Harvey, R.J., Betz, H. and Wassle, H. (2003) Diversity of glycine receptors in the mouse retina: localization of the alpha3 subunit. Journal of Comparative Neurology, 465 (4). pp. 524-539. 10.1002/cne.10852.

Rees, M.I., Harvey, K., Ward, H., White, J.H., Evans, L., Duguid, I.C., Hsu, C.C., Coleman, S.L., Miller, J., Baer, K., Waldvogel, H.J., Gibbon, F., Smart, T.G., Owen, M.J., Harvey, R.J. and Snell, R.G. (2003) Isoform heterogeneity of the human gephyrin gene (GPHN), binding domains to the glycine receptor and mutation analysis in hyperekplexia. Journal of Biological Chemistry, 278 . pp. 24688-24696. 10.1074/jbc.M301070200.

Groot-Kormelink, P.J., Beato, M., Finite, C., Harvey, R.J. and Sivilotti, L.G. (2002) Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of alpha1 glycine receptors in HEK293 cells. Journal of Neuroscience Methods, 113 . pp. 207-214. 10.1016/S0165-0270(01)00500-3 .

Bahn, S., Harvey, R.J., Darlison, M.G. and Wisden, W. (2002) Conservation of γ-Aminobutyric Acid Type A Receptor α6 Subunit Gene Expression in Cerebellar Granule Cells. Journal of Neurochemistry, 66 (5). pp. 1810-1818. 10.1046/j.1471-4159.1996.66051810.x.

Hosie, A.M., Dunne, E.L., Harvey, R.J. and Smart, T.G. (2002) Molecular identification of alpha subunit domains mediating zinc inhibition on GABA-A receptors: allosteric interactions with the beta subunit. Nature Neuroscience, 6 . pp. 362-369. 10.1038/nn1030.

Dunne, E.L., Hosie, A.M., Wooltorton, J.R.A., Duguid, I.C., Harvey, K., Moss, S.J., Harvey, R.J. and Smart, T.G. (2002) N-terminal histidine regulates zinc inhibition on the murine GABA-A receptor beta3 subunit. British Journal of Pharmacology, 137 . pp. 29-38. 10.1038/sj.bjp.0704835.

Forster, I.C., Harvey, R.J., Darlison, M.G. and Benson, J.A. (2001) Functional pharmacology of GABA-A receptors containing the chicken gamma4 subunit. European Journal of Pharmacology, 419 . pp. 1-7. 10.1016/S0014-2999(01)00964-5 .

Piechotta, K., Weth, F., Harvey, R.J. and Friauf, E. (2001) Localisation of rat glycine receptor alpha1 and alpha2 subunit transcripts in the developing auditory brainstem. Journal of Comparative Neurology, 438 . pp. 336-352. 10.1002/cne.1319.

Harvey, R.J., Schmieden, V., von Holst, A., Laube, B., Rohrer, H. and Betz, H. (2000) Glycine receptors containing the alpha4 subunit in the embryonic sympathetic nervous system, spinal cord and male genital ridge. European Journal of Neuroscience, 12 (3). pp. 994-1001. 10.1046/j.1460-9568.2000.00993.x.

Harvey, R.J., Thomas, P., James, C.H., Wilderspin, A.F. and Smart, T.G. (1999) Identification of an inhibitory Zn2+ binding site on the human glycine receptor alpha1 subunit. Journal of Physiology, 520 (1). pp. 53-64. 10.1111/j.1469-7793.1999.00053.x.

Harvey, R.J., Harder, S. and Darlison, M.G. (1999) Reliable and accurate sequencing of lambda, cosmid and P1 DNAs using modified dye terminator reaction parameters. Technical TIPS Online (T01612).

Betz, H., Kuhse, J., Schmieden, V., Laube, B., Kirsch, J. and Harvey, R.J. (1999) Structure and Functions of Inhibitory and Excitatory Glycine Receptors. Annals of the New York Academy of Sciences, 868 (1 ). p. 667. 10.1111/j.1749-6632.1999.tb11343.x.

Liu, S.C., Parent, L., Harvey, R.J., Darlison, M.G. and Barnes, E.M. (1998) Chicken GABA(A) receptor beta4 subunits form robust homomeric GABA-gated channels in Xenopus oocytes. European Journal of Pharmacology, 354 (2-3). pp. 253-259. 10.1016/S0014-2999(98)00453-1.

Harvey, R.J., McCabe, B.J., Solomonia, R.O., Horn, G. and Darlison, M.G. (1998) Expression of the GABAAreceptor γ4-subunit gene: anatomical distribution of the corresponding mRNA in the domestic chick forebrain and the effect of imprinting training. European Journal of Neuroscience, 10 (9). pp. 3024-3028. 10.1111/j.1460-9568.1998.00354.x.

Baylis, H.A., Matsuda, K., Squire, M.D., Fleming, J.T., Harvey, R.J., Darlison, M.G., Barnard, E.A. and Sattelle, D.B. (1997) ACR-3, a Caenorhabditis elegans nicotinic acetylcholine receptor subunit. Molecular cloning and functional expression. Receptors & Channels, 5 (3-4). pp. 149-158.

Harvey, R.J., Stühmer, T., Van Minnen, J. and Darlison, M.G. (1997) Differential patterns of expression of two novel invertebrate (Lymnaea stagnalis) ionotropic glutamate receptor genes. Neuroscience Research Communications, 20 (1). pp. 31-40. 10.1002/(SICI)1520-6769(199701)20:1<31::AID-NRC183>3.0.CO;2-6.

Boehm, S., Harvey, R.J., von Holst, A., Rohrer, H. and Betz, H. (1997) Glycine receptors in cultured chick sympathetic neurons are excitatory and trigger neurotransmitter release. Journal of Physiology, 504 (3). pp. 683-694. 10.1111/j.1469-7793.1997.683bd.x.

Albrecht, B.E., Breitenbach, U., Stühmer, T., Harvey, R.J. and Darlison, M.G. (1997) In situ hybridization and reverse transcription--polymerase chain reaction studies on the expression of the GABA(C) receptor rho1- and rho2-subunit genes in avian and rat brain. European Journal of Neuroscience, 9 (11). pp. 2414-2422.

Harvey, R.J. and Darlison, M.G. (1997) In Situ Hybridization Localization of the GABAA Receptor β2S- and β2L-Subunit Transcripts Reveals Cell-Specific Splicing of Alternate Cassette Exons. Neuroscience, 77 (2). pp. 361-369. 10.1016/S0306-4522(96)00467-8.

Darlison, M.G., Greten, F.R., Harvey, R.J., Kreienkamp, H.J., Stühmer, T., Zwiers, H., Lederis, K. and Richter, D. (1997) Opioid receptors from a lower vertebrate (Catostomus commersoni): sequence, pharmacology, coupling to a G-protein-gated inward-rectifying potassium channel (GIRK1), and evolution. Proceedings of the National Academy of Sciences of the United States of America, 94 (15). pp. 8214-8219. 10.1073/pnas.94.15.8214.

Bahn, S., Harvey, R.J., Darlison, M.G. and Wisden, W. (1996) Conservation of gamma-aminobutyric acid type A receptor alpha 6 subunit gene expression in cerebellar granule cells. Journal of Neurochemistry, 66 (5). pp. 1810-1818. 10.1046/j.1471-4159.1996.66051810.x.

Stühmer, T., Amar, M., Harvey, R.J., Bermudez, I., Van Minnen, J. and Darlison, M.G. (1996) Structure and pharmacological properties of a molluscan glutamate-gated cation channel and its likely role in feeding behavior. Journal of Neuroscience, 16 (9). pp. 2869-80.

Bhandal, N.S., Ramsey, R.L., Harvey, R.J., Darlison, M.G. and Usherwood, P.N.R. (1995) Channel gating in the absence of agonist by a homooligomeric molluscan GABA receptor expressed inXenopus oocytes from a cloned cDNA. Invertebrate Neuroscience, 1 (3). pp. 267-272. 10.1007/BF02211028.

Harvey, R.J., Lobron, C., Reinhardt-Maelicke , S., Maelicke, A. and Darlison, M.G. (1995) The embryonal carcinoma cell line PCC7-S-AzaR1 (clone 1009) expresses a functional GABAA receptor comprising the [alpha]5, [beta]3 and [gamma]3 subunits: 21.2.(Poster). Behavioural Pharmacology, 6 . pp. 119-120.

Smith, L.A., Amar, M., Harvey, R.J., Darlison, M.G., Earley, F.G.P., Beadle, D.J., King, L.A. and Bermudez, I. (1995) The Production of a Stably Transformed Insect Cell Line Expressing An Invertebrate GABAAReceptor β-Subunit. Journal of Receptors and Signal Transduction, 15 (1-4). pp. 33-41. 10.3109/10799899509045205.

Harvey, R.J., Chinchetru, M.A. and Darlison, M.G. (1994) Alternative Splicing of a 51-Nucleotide Exon that Encodes a Putative Protein Kinase C Phosphorylation Site Generates Two Forms of the Chicken γ-Aminobutyric AcidAReceptor β2 Subunit. Journal of Neurochemistry, 62 (1). pp. 10-16. 10.1046/j.1471-4159.1994.62010010.x.

Coon, H., Hicks, A.A., Bailey, M.E., Hoff, M., Holik, J., Harvey, R.J., Johnson, K.J., Darlison, M.G., Reimherr, F. and Wender, P. (1994) Analysis of GABAA receptor subunit genes in multiplex pedigrees with manic depression. Psychiatric Genetics, 4 (3). pp. 185-191.

Baumgartner, B.J., Harvey, R.J., Darlison, M.G. and Barnes, E.M. (1994) Developmental up-regulation and agonist-dependent down-regulation of GABAA receptor subunit mRNAs in chick cortical neurons. Molecular Brain Research, 26 (1-2). pp. 9-17. 10.1016/0169-328X(94)90068-X.

Harvey, R.J., Kim, H-C. and Darlison, M.G. (1994) Expression patterns of the GABA(A) receptor α1-,β2-,γ2- and γ4-subunit genes in chick retina. Neuroscience Research Communications, 15 (2). pp. 95-102.

Hutton, M., Harvey, R.J., Earley, F., Barnard, E.A. and Darlison, M.G. (1993) A novel invertebrate GABAA receptor-like polypeptide Sequence and pattern of gene expression. FEBS Letters, 326 (1-3). pp. 112-116. 10.1016/0014-5793(93)81773-S.

Darlison, M.G., Stühmer, T., Harvey, R.J., Dautzenberg, F.M., Kim, H-C., Zimmermann, C., Amar, M., Bermudez, I. and Van Minnen, J. (1993) Molecular Characterisation and Functional Expression of Molluscan Ion-Channel Receptors That Can Be Activated By Either γ-Aminobutyric Acid or L-Glutamate. Netherlands Journal of Zoology, 44 (3-4). pp. 473-485. 10.1163/156854293X00557.

Harvey, R.J., Kim, H-C. and Darlison, M.G. (1993) Molecular cloning reveals the existence of a fourth γ subunit of the vertebrate brain GABAA receptor. FEBS Letters, 331 (3). pp. 211-216. 10.1016/0014-5793(93)80339-V.

Zaman, S.H., Shingai, R., Harvey, R.J., Darlison, M.G. and Barnard, E.A. (1992) Effects of subunit types of the recombinant GABAA receptor on the response to a neurosteroid. European Journal of Pharmacology: Molecular Pharmacology, 225 (4). pp. 321-330. 10.1016/0922-4106(92)90106-6.

Zaman, S.H., Harvey, R.J., Barnard, E.A. and Darlison, M.G. (1992) Unusual effects of benzodiazepines and cyclodiene insecticides on an expressed invertebrate GABAA receptor. FEBS Letters, 307 (3). pp. 351-354. 10.1016/0014-5793(92)80711-O.

Hutton, M., Harvey, R.J., Barnard, E.A. and Darlison, M.G. (1991) Cloning of a cDNA that encodes an invertebrate glutamate receptor subunit. FEBS Letters, 292 (1-2). pp. 111-114. 10.1016/0014-5793(91)80846-U.

Harvey, R.J. and Darlison, M.G. (1991) Random-primed cDNA synthesis facilitates the isolation of multiple 5'-cDNA ends by RACE. Nucleic Acids Research, 19 (14). p. 4002. 10.1093/nar/19.14.4002.

Harvey, R.J., Vreugdenhil, E., Zaman, S.H., Bhandal, N.S., Usherwood, P.N., Barnard, E.A. and Darlison, M.G. (1991) Sequence of a functional invertebrate GABAA receptor subunit which can form a chimeric receptor with a vertebrate alpha subunit. EMBO Journal, 10 (11). pp. 3239-45.

Bateson, A.N., Harvey, R.J., Wisden, W., Glencorse, T., Hicks, A., Hunt, S., Barnard, E.A. and Darlison, M.G. (1991) The chicken GABAA receptor α1 subunit: cDNA sequence and localization of the corresponding mRNA. (Short communication). Molecular Brain Research, 9 (4). pp. 333-339. 10.1016/0169-328X(91)90081-8.

Bateson, A.N., Harvey, R.J., Bloks, C.C.M. and Darlison, M.G. (1990) Sequence of the chicken GABAA receptor β3-subunit cDNA. Nucleic Acids Research, 18 (18). p. 5557. 10.1093/nar/18.18.5557.

Book Section

Stephenson, J.B.P., Harvey, K., Harvey, R.J. and Rees, M.I. (2012) Hyperekplexia: a glycinergic disorder. In: Channelopathies of the nervous system in childhood. MacKeith Press. (In Press)

Conference or Workshop Item

Tretter, V., Kerschner, B., Ramsden, S., Saiepour, L., Harvey, R.J., Moss, S.J., Sieghart, W. and Harvey, K. (2010) Characterization of the binding site between the GABAA receptor3 subunit and gephyrin. In: 7th Forum of European Neuroscience Meeting, 3-7 July 2010, Amsterdam.

James, V., Carta, E., Topf, M. and Harvey, R.J. (2010) Defective glycinergic transmission in zebrafish motility mutants. In: 1st Zebrafish Pl Meeting, 18-21 April 2010, Padua, Italy .

This list was generated on Wed Apr 16 20:01:40 2014 BST.