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Number of items: 41.

Article

Shiu, W.K.P., Rahman, M.M., Curry, J., Stapleton, P.D., Zloh, M., Malkinson, J.P. and Gibbons, S. (2012) Antibacterial Acylphloroglucinols from Hypericum olympicum. Journal of Natural Products, 75 (3). pp. 336-343. 10.1021/np2003319.

Brucoli, F., Natoli, A., Marimuthu, P., Borrello, M.T., Stapleton, P.D., Gibbons, S. and Schatzlein, A.G. (2012) Efficient synthesis and biological evaluation of proximicins A, B and C. Bioorganic and Medicinal Chemistry, 20 (6). pp. 2019-2024. 10.1016/j.bmc.2012.01.043.

Guimaraes, A.M.R., Fuente, M.de la, Stapleton, P.D., Ji, X., Oliyide, A.O., Osbourn, A., Pandit, S., Bowles, D.J., Davis, B.G., Schatzlein, A.G. and Yang, M. (2011) Abstract: Glycosylation enhances selectivity of novobiocin and alters antibacterial mechanism. Abstract of Papers of the American Chemical Society, 241 (132-CARB).

Patel, S.M., Fuente, M.de la, Ke, S., Guimarães, A.M.R., Oliyide, A.O., Ji, X., Stapleton, P.D., Osbourn, A., Pan, Y., Bowles, D.J., Davis, B.G., Schatzlein, A.G. and Yang, M. (2011) High throughput discovery of heteroaromatic-modifying enzymes allows enhancement of novobiocin selectivity. Chemical Communications, 47 (38). pp. 10569-10571. 10.1039/C1CC13552J .

Albasarah, Y.Y., Somavarapu, S., Stapleton, P.D. and Taylor, K.M.G. (2010) Chitosan-coated antifungal formulations for nebulisation. Journal of Pharmacy and Pharmacology, 62 (7). pp. 821-828. 10.1211/jpp.62.07.0002.

Somavarapu, S., Taylor, K.M.G., Stapleton, P.D., Albasarah, Y.Y., Schaeffer, F. and Pitarresi, G. (2009) Abstract: Amphiphilic graft copolymer of hyaluronic acid and polylactic acid for pulmonary delivery of amphotericin B. Journal of Pharmacy and Pharmacology, 61 (Suppl.). A21-A22. 10.1211/002235709789037008.

Shah, S., Stapleton, P.D. and Taylor, P.W. (2008) The polyphenol (-)- epicatechin gallate disrupts the secretion of virulence-related proteins by Staphylococcus aureus. Letters In Applied Microbiology, 46 (2). pp. 181-185. 10.1111/j.1472-765X.2007.02296.x.

Stapleton, P.D., Shah, S., Ehlert, K., Hara, Y. and Taylor, P.W. (2007) Effect of the beta-lactam-resistance modifier(-)-epicatechin gallate on the architecture of the cell wall of Staphylococcus aureus. Microbiology, 153 . pp. 2093-2103. 10.1099/mic.0.2007/007807-0.

Hadjivassileva, T., Stapleton, P.D., Thurston, D.E. and Taylor, P.W. (2007) Interactions of pyrrolobenzodiazepine dimers and duplex DNA from methicillin-resistant Staphylococcus aureus. International Journal of Antimicrobial Agents, 29 (6). pp. 672-678. 10.1016/j.ijantimicag.2007.01.005 .

Stapleton, P.D., Gettert, J. and Taylor, P.W. (2006) Epicatechin gallate, a component of green tea, reduces hatotolerance in Staphylococcus aureus. International Journal of Food Microbiology, 111 (3). pp. 276-279. 10.1016/j.ijfoodmicro.2006.06.005 .

Rosado, H., Stapleton, P.D. and Taylor, P.W. (2006) Effect of simulated microgravity on the virulence properties of the opportunistic bacterial pathogen Staphylococcus aureus. Proceedings of the 57th International Astronautical federation Congress .

Stapleton, P.D., Shah, S., Hara, Y. and Taylor, P.W. (2006) Potentiation of catechin gallate-mediated sensitization of Staphylococcus aureus to oxacilin by non-galloylated catechins. Antimicrobial Agents and Chemotherapy, 50 . pp. 752-755. 10.1128/AAC.50.2.752-755.2006.

Anderson, J.C., Headley, C., Stapleton, P.D. and Taylor, P.W. (2005) Synthesis and antibacterial activity of hydrolytically stable (-)-epicatechin gallate analogues and their modulation of beta-lactam resistance in Staphylococcus aureus. Bioorganic and Medicinal Chemistry Letters, 15 (10). pp. 2633-2635. 10.1016/j.bmcl.2005.03.063.

Taylor, P.W., Hamilton-Miller, J.M.T. and Stapleton, P.D. (2005) Antimicrobial properties of green tea catechins. Food Science and Technology Bulletin, 2 . pp. 71-81.

Anderson, J.C., Headley, C., Stapleton, P.D. and Taylor, P.W. (2005) Asymmetric total synthesis of B-ring modified (-)-epicatechin gallate analogues and their modulation of beta-lactam resistance in Staphylococcus aureus. Tetrahedron, 61 . pp. 7703-7711. 10.1016/j.tet.2005.05.086.

Hadjivassileva, T., Stapleton, P.D., Thurston, D.E. and Taylor, P.W. (2005) Pyrrolobenzodiazepine dimers: novel sequence-selective, DNA-interactive, cross-linking agents with activity against Gram-positive bacteria. Journal of Antimicrobial Chemotherapy, 56 (3). pp. 513-518. 10.1093/jac/dki256.

Stapleton, P.D., Adams, V., Pike, R., Lucas, G., Roberts, P. and Mullany, R. (2004) Characterisation of viridans group streptococci with different levels of Tet(M)-mediated tetracycline resistance. International Journal of Antimicrobial Agents, 24 (5). pp. 439-443. 10.1016/j.ijantimicag.2004.06.003 .

Stapleton, P.D., Shah, S., Hamilton-Miller, J.M.T., Hara, Y., Nagaoka, Y., Kumagai, A., Uesato, S. and Taylor, P.W. (2004) Anti-Staphylococcus aureus activity and oxacillin resistance modulating capacity of 3-0-actyl-catechins. International Journal of Antimicrobial Agents, 24 (4). pp. 374-380. 10.1016/j.ijantimicag.2004.03.024.

Stapleton, P.D., Shah, S., Anderson, J.C., Hara, Y. and Hamilton-Miller, J.M.T. (2004) Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates. International Journal of Antimicrobial Agents, 23 (5). pp. 462-467. 10.1016/j.ijantimicag.2003.09.027 .

Stapleton, P.D., Pike, R., Mullany, P., Lucas, V., Roberts, G., Rowbury, M., Wilson, M. and Richards, H. (2004) Mercuric resistance genes in gram-positive oral bacteria. FEMS Microbiology Letters, 236 . pp. 213-220. 10.1111/j.1574-6968.2004.tb09649.x .

Taylor, P.W., Stapleton, P.D., Shah, S. and Anderson, J.C. (2004) Modification of staphylococci by catechin gallates. ICOS Proceedings, 2 . pp. 414-417.

Stapleton, P.D., Shah, S., Anderson, J.C., Hara, Y., Hamilton-Miller, J.M.T. and Taylor, P.W. (2004) Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates. International Journal of Antimicrobial Agents, 23 (5). pp. 462-467. 10.1016/j.ijantimicag.2003.09.027.

Pike, R., Lucas, V., Petrie, A., Roberts, G., Stapleton, P.D., Rowbury, R., Richards, H., Mullany, P. and Wilson, M. (2003) Effect of restoration of children's teeth with mercury amalgam on the prevalence of mercury- and antibiotic-resistant oral bacteria. Microbial Drug Resistance, 9 (1). pp. 93-97. 10.1089/107662903764736391.

Taylor, P.W. and Stapleton, P.D. (2002) Structural pharmacogenomics: the answer to antimicrobial drug resistance? Drug Discovery Today, 8 (3). pp. 110-111. 10.1016/S1359-6446(02)02591-6.

Pike, R., Stapleton, P.D., Lucas, V., Roberts, G., Rowbury, R., Richards, H., Mullany, P. and Wilson, M. (2002) Effect of Medium Composition on the Susceptibility of Oral Streptococci to Mercuric Chloride. Current Microbiology, 45 (4). pp. 272-276. 10.1007/s00284-002-3754-1.

Stapleton, P.D. and Taylor, P.W. (2002) Methicillin resistance in staphylococcus aureus: mechanisms and modulation. Science Progress, 85 (1). pp. 57-72.

Taylor, P.W., Stapleton, P.D. and Luzio, J.P. (2002) New ways to treat bacterial infections. Drug Discovery Today, 7 (21). pp. 1086-1091. 10.1016/S1359-6446(02)02498-4.

Pike, R., Lucas, V., Stapleton, P.D., Gilthorpe, G., Roberts, R., Rowbury, H., Richards, P., Mullany, P. and Wilson, M. (2002) Prevalence and antibiotic resistance profile of mercury-resistant oral bacteria from children with and without mercury amalgam fillings. Journal of Antimicrobial Chemotherapy, 49 (5). p. 777. 10.1093/jac/dkf019.

Stapleton, P.D., Shannon, K.P. and French, G.L. (1999) Carbapenem resistance in Escherichia coli associated with plasmid-determined CMY-4 beta-lactamase production and loss of an outer membrane protein. Antimicrobial Agents and Chemotherapy, 43 (5). pp. 1206-1210.

Stapleton, P.D., Shannon, K.P. and French, G.L. (1999) Construction and Characterization of Mutants of the TEM-1 b-Lactamase Containing Amino Acid Substitutions Associated with both Extended-Spectrum Resistance and Resistance to b-Lactamase Inhibitors. Antimicrobial Agents and Chemotherapy, 43 (8). pp. 1881-1887.

Shannon, K.P., Fung, K-W., Stapleton, P.D., Anthony, R., Power, E. and French, G.L. (1998) A hospital outbreak of extended-spectrum β-lactamase-producing Klebsiella pneumoniae investigated by RAPD typing and analysis of the genetics and mechanisms of resistance. Journal of Hospital Infection, 39 (4). pp. 291-300. 10.1016/S0195-6701(98)90294-8.

Revathi, G, Shannon, K.P., Stapleton, P.D., Jain, B.K. and French, G.L. (1998) An outbreak of extended-spectrum, β-lactamase-producing Salmonella senftenberg in a burns ward. Journal of Hospital Infection, 40 (4). pp. 295-302. 10.1016/S0195-6701(98)90307-3.

Shannon, K.P., Stapleton, P.D., Xiang, X., Johnson, A., Beattie, H., El Bakri, F., Cookson, B. and French, G.L. (1998) Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Strains Causing Nosocomial Outbreaks of Infection in the United Kingdom. Journal of Clinical Microbiology, 36 (10). pp. 3105-3110.

Stapleton, P.D., Shannon, K.P. and Phillips, I. (1995) DNA sequence differences of ampD mutants of Citrobacter freundii. Antimicrobial Agents and Chemotherapy, 39 (11). pp. 2494-2498.

Stapleton, P.D., Wu, P.J., King, A., Shannon, K.P., French, G.L. and Phillips, I. (1995) Incidence and mechanisms of resistance to the combination of amoxicillin and clavulanic acid in Escherichia coli. Antimicrobial Agents and Chemotherapy, 39 (11). pp. 2478-2483.

Stapleton, P.D., Shannon, K.P. and Phillips, I. (1995) The ability of beta-lactam antibiotics to select mutants with derepressed beta-lactamase synthesis from Citrobacter freundii. Journal of Antimicrobial Chemotherapy, 36 (3). pp. 483-496. 10.1093/jac/36.3.483.

Cookson, B.D., Stapleton, P.D. and Ludlam, H. (1992) Ribotyping of coagulase-negative staphylococci. Journal of Medical Microbiology, 36 (6). pp. 414-419.

Cookson, B.D., Farrelly, H., Stapleton, P.D., Garvey, R.P. and Price, M.R. (1991) Letter to the editor: Transferable resistance to triclosan in MRSA. Lancet, 337 (8756). pp. 1548-1549. 10.1016/0140-6736(91)93242-2 .

Patent

School of Pharmacy (2005) Compositions and methods of sensitizing methicillin resistant Staphylococcus aureus to oxacillin. 100799.0017.

School of Pharmacy (2004) Compounds for use in the treatment of infection. HMJ03770GB.

School of Pharmacy (2003) Antimicrobial compositions and methods of use. 100799.0003.

This list was generated on Tue Jul 22 08:47:00 2014 BST.