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Number of items: 56.

Article

Anderson, J.C., McCarthy, R.A., Paulin, S. and Taylor, P.W. (2011) Anti-staphylococcal activity and β-lactam resistance attenuating capacity of structural analogues of (−)-epicatechin gallate. Bioorganic & Medicinal Chemistry Letters, 21 (23). pp. 6996-7000. 10.1016/j.bmcl.2011.09.116.

Putcha, L., Taylor, P.W. and Boyd, J.L. (2011) Biopharmaceutical challenges of therapeutics in space: formulation and packaging considerations. Therapeutic Delivery, 2 (11). pp. 1373-1376. 10.4155/tde.11.115.

Rosado, H., O’Neill, A.J., Blake, K., Walther, M., Long, P.F., Hinds, J. and Taylor, P.W. (2011) Rotating wall vessel alters protein secretion and global gene expression by Staphylococcus aureus. International Journal of Astrobiology, 11 (2). pp. 71-81.

Rosado, H., Rahman, K.M., Feuerbaum, E-A., Hinds, J., Thurston, D.E. and Taylor, P.W. (2011) The minor groove-binding agent ELB-21 forms multiple interstrand and intrastrand covalent cross-links with duplex DNA and displays potent bactericidal activity against methicillin-resistant Staphylococcus aureus. Journal of Antimicrobial Chemotherapy, 66 (5). pp. 985-996. 10.1093/jac/dkr044.

Zelmer, A., Martin, M.J., Gundogdu, O., Birchenough, G., Lever, R., Wren, B.W., Luzio, J.P. and Taylor, P.W. (2010) Administration of capsule-selective endosialidase E minimizes upregulation of organ gene expression induced by experimental systemic infection with Escherichia coli K1. Microbiology, 156 (7). pp. 2205-2215. 10.1099/mic.0.036145-0.

Bernal, P., Lemaire, S., Pinho, M.G., Mobashery, S., Hinds, J. and Taylor, P.W. (2010) Insertion of epicatechin gallate into the cytoplasmic membrane of methicillin-resistant Staphylococcus aureus disrupts penicillin-binding protein (PBP) 2A-mediated β-lactam resistance by delocalizing PBP2. Journal of Biological Chemistry, 285 . pp. 24055-24065. 10.1074/jbc.M110.114793 .

Glonti, T., Chanishvili, N. and Taylor, P.W. (2010) Bacteriophage-derived enzyme that depolymerizes the alginic acid capsule associated with cystic fibrosis isolates of Pseudomonas aeruginosa. Journal of Applied Microbiology, 108 (2). pp. 695-702. 10.1111/j.1365-2672.2009.04469.x.

Glonti, T., Chanishvili, N. and Taylor, P.W. (2010) Bacteriophage-derived enzyme that depolymerizes the alginic acid capsule associated with cystic fibrosis isolates ofPseudomonas aeruginosa. Journal of Applied Microbiology, 108 (2). pp. 695-702. 10.1111/j.1365-2672.2009.04469.x.

Bernal, P., Lemaire, S., Pinho, M.G., Mobashery, S., Hinds, J. and Taylor, P.W. (2010) Insertion of epicatechin gallate into the cytoplasmic membrane of methicillin-resistant Staphylococcus aureus disrupts penicillin-binding protein (PBP) 2a-mediated beta-lactam resistance by delocalizing PBP2. Journal of Biological Chemistry, 285 (31). pp. 24055-24065. 10.1074/jbc.M110.114793.

Rosado, H., Doyle, M., Hinds, J. and Taylor, P.W. (2010) Low-shear modelled microgravity alters expression of virulence determinants of Staphylococcus aureus. Acta Astronautica, 66 (3-4). pp. 408-413. 10.1016/j.actaastro.2009.06.007 .

Taylor, P.W., Arnet, I., Fischer, A. and Simpson, I.N. (2010) Pharmaceutical quality of nine generic orlistat products compared with Xenical(r). Obesity facts, 3 (4). pp. 231-237. 10.1159/000319450.

Doyle, M., Feuerbaum, E-A., Fox, K.R., Hinds, J., Thurston, D.E. and Taylor, P.W. (2009) Response of Staphylococcus aureus to subinhibitory concentrations of a sequence-selective, DNA minor groove binding cross-linking pyrrolobenzodiazepine dimer. Journal of Antimicrobial Chemotherapy, 64 (5). pp. 949-959. 10.1093/jac/dkp325 .

Bernal, P., Zloh, M. and Taylor, P.W. (2009) Disruption of D-alanyl esterification of Staphylococcus aureus cell wall teichoic acid by the beta-lactam-resistance modifier(-)-epicatechin gallate. Journal of Antimicrobial Chemotherapy, 63 (6). pp. 1156-1162. 10.1093/jac/dkp094.

Kim, C.E., Griffiths, W.J. and Taylor, P.W. (2009) Components derived from Pelargonium stimulate macrophage killing of Mycobacterium species. Journal of Applied Microbiology, 106 . pp. 1184-1193. 10.1111/j.1365-2672.2008.04085.x.

Cushnie, T.P., Taylor, P.W., Nagaoka, Y., Uesato, S., Hara, Y. and Lamb, A.J. (2008) Investigation of the antibacterial activity of 3-O-octanoyl-(-)-epicatechin. Journal of Applied Microbiology, 105 (5). pp. 1461-1469. 10.1111/j.1365-2672.2008.03881.x.

Zelmer, A., Bowen, M., Jokilammi, A., Finne, J., Luzio, J.P. and Taylor, P.W. (2008) Differential expression of the polysialyl capsule during blood-to-brain transit of neuropathogenic Escherichia coli K1. Microbiology, 154 (8). pp. 2522-2532. 10.1099/mic.0.2008/017988-0.

Taylor, P.W. (2008) An anti-bac alert. Public Service Review: Health, 18 (25 February).

Shah, S., Stapleton, P.D. and Taylor, P.W. (2008) The polyphenol (-)- epicatechin gallate disrupts the secretion of virulence-related proteins by Staphylococcus aureus. Letters In Applied Microbiology, 46 (2). pp. 181-185. 10.1111/j.1472-765X.2007.02296.x.

Stapleton, P.D., Shah, S., Ehlert, K., Hara, Y. and Taylor, P.W. (2007) Effect of the beta-lactam-resistance modifier(-)-epicatechin gallate on the architecture of the cell wall of Staphylococcus aureus. Microbiology, 153 . pp. 2093-2103. 10.1099/mic.0.2007/007807-0.

Hadjivassileva, T., Stapleton, P.D., Thurston, D.E. and Taylor, P.W. (2007) Interactions of pyrrolobenzodiazepine dimers and duplex DNA from methicillin-resistant Staphylococcus aureus. International Journal of Antimicrobial Agents, 29 (6). pp. 672-678. 10.1016/j.ijantimicag.2007.01.005 .

Cushnie, T.P., Hamilton, V.E., Chapman, D.G., Taylor, P.W. and Lamb, A.J. (2007) Aggregation of Staphylococcus aureus following treatment with the antibacterial flavonol galangin. Journal of Applied Microbiology, 103 (4). pp. 1562-1567. 10.1111/j.1365-2672.2007.03393.x.

Stapleton, P.D., Gettert, J. and Taylor, P.W. (2006) Epicatechin gallate, a component of green tea, reduces hatotolerance in Staphylococcus aureus. International Journal of Food Microbiology, 111 (3). pp. 276-279. 10.1016/j.ijfoodmicro.2006.06.005 .

Taylor, P.W. and Brown, M. (2006) Advancing phamacy education and research through Maplethorpe fellowships. Pharmaceutical Journal, 276 . pp. 208-213.

Rosado, H., Stapleton, P.D. and Taylor, P.W. (2006) Effect of simulated microgravity on the virulence properties of the opportunistic bacterial pathogen Staphylococcus aureus. Proceedings of the 57th International Astronautical federation Congress .

Taylor, P.W. (2006) Pharmaceutical quality of generic isotretinoin products, compared to Roaccutane. Current Medical Research and Opinion, 22 (3). pp. 603-615. 10.1185/030079906X96326.

Stapleton, P.D., Shah, S., Hara, Y. and Taylor, P.W. (2006) Potentiation of catechin gallate-mediated sensitization of Staphylococcus aureus to oxacilin by non-galloylated catechins. Antimicrobial Agents and Chemotherapy, 50 . pp. 752-755. 10.1128/AAC.50.2.752-755.2006.

Taylor, P.W. (2005) Towards rational treatment of bacterial infections during extended space flight. International Journal of Antimicrobial Agents, 26 (3). pp. 183-187. 10.1016/j.ijantimicag.2005.06.002.

Anderson, J.C., Headley, C., Stapleton, P.D. and Taylor, P.W. (2005) Synthesis and antibacterial activity of hydrolytically stable (-)-epicatechin gallate analogues and their modulation of beta-lactam resistance in Staphylococcus aureus. Bioorganic and Medicinal Chemistry Letters, 15 (10). pp. 2633-2635. 10.1016/j.bmcl.2005.03.063.

Taylor, P.W., Hamilton-Miller, J.M.T. and Stapleton, P.D. (2005) Antimicrobial properties of green tea catechins. Food Science and Technology Bulletin, 2 . pp. 71-81.

Anderson, J.C., Headley, C., Stapleton, P.D. and Taylor, P.W. (2005) Asymmetric total synthesis of B-ring modified (-)-epicatechin gallate analogues and their modulation of beta-lactam resistance in Staphylococcus aureus. Tetrahedron, 61 . pp. 7703-7711. 10.1016/j.tet.2005.05.086.

Rowland, R.E.S., Taylor, P.W. and Florence, A.T. (2005) Attachment, uptake and transport of nanoparticles coated with an internalin A fragment through a Caco-2 monolayer. Drug Delivery Science and Technology, 15 . pp. 313-317.

Hadjivassileva, T., Stapleton, P.D., Thurston, D.E. and Taylor, P.W. (2005) Pyrrolobenzodiazepine dimers: novel sequence-selective, DNA-interactive, cross-linking agents with activity against Gram-positive bacteria. Journal of Antimicrobial Chemotherapy, 56 (3). pp. 513-518. 10.1093/jac/dki256.

Taylor, P.W., Maalim, S. and Coleman, S. (2005) The strange story of Umckaloabo. Pharmaceutical Journal, 275 . pp. 790-792.

Mushtaq, N., Redpath, M.B., Luzio, J.P. and Taylor, P.W. (2005) Treatment of experimental Escherichia coli infecton with recombinant bacteriophage-derived capsule depolymerase. Journal of Antimicrobial Chemotherapy, 56 . pp. 160-165. 10.1093/jac/dki177.

Stapleton, P.D., Shah, S., Hamilton-Miller, J.M.T., Hara, Y., Nagaoka, Y., Kumagai, A., Uesato, S. and Taylor, P.W. (2004) Anti-Staphylococcus aureus activity and oxacillin resistance modulating capacity of 3-0-actyl-catechins. International Journal of Antimicrobial Agents, 24 (4). pp. 374-380. 10.1016/j.ijantimicag.2004.03.024.

Hitch, G., Pratten, J. and Taylor, P.W. (2004) Isolation of bacteriophages from the oral cavity. Letters In Applied Microbiology, 39 (2). pp. 215-219. 10.1111/j.1472-765X.2004.01565.x.

Seidel, V. and Taylor, P.W. (2004) In vitro activity of extracts and constituents of Pelargonium against rapidly growing mycobacteria. International Journal of Antimicrobial Agents, 23 (6). pp. 613-619. 10.1016/j.ijantimicag.2003.11.008.

Mushtaq, N., Redpath, M.B., Luzio, J.P. and Taylor, P.W. (2004) Prevention and cure of systemic Escherichia coli K1 infection by modification of the bacterial phenotype. Antimicrobial Agents and Chemotherapy, 48 (5). pp. 1503-1508. 10.1128/AAC.48.5.1503-1508.2004.

Taylor, P.W., Stapleton, P.D., Shah, S. and Anderson, J.C. (2004) Modification of staphylococci by catechin gallates. ICOS Proceedings, 2 . pp. 414-417.

Stapleton, P.D., Shah, S., Anderson, J.C., Hara, Y., Hamilton-Miller, J.M.T. and Taylor, P.W. (2004) Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates. International Journal of Antimicrobial Agents, 23 (5). pp. 462-467. 10.1016/j.ijantimicag.2003.09.027.

Taylor, P.W., Seidel, V. and Gillespie, S.H. (2003) "Umckaloabo" - a South African herbal remedy for tuberculosis? Antibiotics Chemotherapy, 7 . pp. 10-11.

Taylor, P.W. (2003) Anti-mycobacterial activity of indigenous South African plants. South African Medical Journal, 93 . pp. 904-907.

Leggate, D.R., Bryant, J.M., Redpath, M.B., Head, D., Taylor, P.W. and Luzio, J.P. (2002) Expression, mutagenesis and kinetic analysis of recombinant K1E endosialidase to define the site of proteolytic processing and the requirement for a specific aspartate residue in catalysis. Molecular Microbiology, 44 (3). pp. 749-760. 10.1046/j.1365-2958.2002.02908.x.

Taylor, P.W. and Stapleton, P.D. (2002) Structural pharmacogenomics: the answer to antimicrobial drug resistance? Drug Discovery Today, 8 (3). pp. 110-111. 10.1016/S1359-6446(02)02591-6.

Hamilton-Miller, J.M.T. and Taylor, P.W. (2002) Antimicrobial activity of Japanese green tea: present position and future prospects. ICOS Proceedings III . pp. 261-263.

Stapleton, P.D. and Taylor, P.W. (2002) Methicillin resistance in staphylococcus aureus: mechanisms and modulation. Science Progress, 85 (1). pp. 57-72.

Taylor, P.W., Stapleton, P.D. and Luzio, J.P. (2002) New ways to treat bacterial infections. Drug Discovery Today, 7 (21). pp. 1086-1091. 10.1016/S1359-6446(02)02498-4.

Brandon, N.J., Bedford, F.K., Connolly, C.N., Couve, A., Kittler, J.T., Hanley, J.G., Jovanovic, J.N., Uren, J., Taylor, P.W., Thomas, P., Smart, T.G. and Moss, S.J. (1999) Synaptic targeting and regulation of GABA(A) receptors. Biochemical Society Transactions, 27 (4). pp. 527-530. 10.1042/bst0270527 .

Book Section

Putcha, L. and Taylor, P.W. (2011) Stability of medications in space: therapeutic implications for extended duration space missions. In: Advances in Engineering Research. Vol. 1. Nova Science, Hauppauge, NY, pp. 221-239. ISBN 978-1612097985.

Taylor, P.W., Bernal, P. and Zelmer, A. (2009) Modification of the bacterial phenotype as an approach to counter the emergence of multidrug-resistant pathogens. In: Antibiotic Resistance: Causes and Risk Factors, Mechanisms and Alternatives. Nova Science Publishers, Hauppauge, New York, USA, pp. 43-78. ISBN 978-1-60741-623-4.

Taylor, P.W. and Rosado, H. (2008) Manned Missions to Mars: The Likely Impact of Microbial Infection. In: Planet Mars Research Focus. Nova Science, New York, USA, p. 165. ISBN 978-1-60021-826-2.

Rosado, H., Doyle, M., Hinds, J. and Taylor, P.W. (2008) Abstract: Low-shear modelled microgravity alters expression of virulence determinants by Staphylococcus aureus. In: Proceedings of the 59th International Astronautical Federation Congress IAC-08. IAC, A1 7.-A2 7.5.

Patent

School of Pharmacy (2005) Compositions and methods of sensitizing methicillin resistant Staphylococcus aureus to oxacillin. 100799.0017.

School of Pharmacy (2004) Pyrrolobenzodiazepines. RJWL/LP6165765.

School of Pharmacy (2004) Compounds for use in the treatment of infection. HMJ03770GB.

School of Pharmacy (2003) Antimicrobial compositions and methods of use. 100799.0003.

This list was generated on Fri Oct 24 03:58:09 2014 BST.