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Number of items: 13.

Article

Guimaraes, A.M.R., Fuente, M.de la, Stapleton, P.D., Ji, X., Oliyide, A.O., Osbourn, A., Pandit, S., Bowles, D.J., Davis, B.G., Schatzlein, A.G. and Yang, M. (2011) Abstract: Glycosylation enhances selectivity of novobiocin and alters antibacterial mechanism. Abstract of Papers of the American Chemical Society, 241 (132-CARB).

Guimaraes, A.M.R., Thurston, D.E. and Yang, M. (2011) Abstract: Glycosylation of novobiocin leads to novel antibiotics and anticancer drugs. Abstract of Papers of the American Chemical Society, 241 (102-CARB).

Patel, S.M., Fuente, M.de la, Ke, S., Guimarães, A.M.R., Oliyide, A.O., Ji, X., Stapleton, P.D., Osbourn, A., Pan, Y., Bowles, D.J., Davis, B.G., Schatzlein, A.G. and Yang, M. (2011) High throughput discovery of heteroaromatic-modifying enzymes allows enhancement of novobiocin selectivity. Chemical Communications, 47 (38). pp. 10569-10571. 10.1039/C1CC13552J .

Nielsen, M.M., Suits, M.D.L., Yang, M., Barry, C.S., Martinez-Fleites, C., Tailford, L.E., Flint, J.E., Dumontet, C., Davis, B.G., Gilbert, H.J. and Davies, G.J. (2011) Substrate and metal ion promiscuity in mannosylglycerate synthase. Journal of Biological Chemistry, 286 (17). pp. 15155-15164. 10.1074/jbc.M110.199844 .

Modarai, M., Yang, M., Suter, A., Kortenkamp, A. and Heinrich, M. (2010) Metabolomic profiling of liquid Echinacea medicinal products with in vitro inhibitory effects on cytochrome P450 3A4 (CYP3A4). Planta Medica, 76 (4). pp. 378-385. 10.1055/s-0029-1186152.

Huebner, A., Bratton, D., Whyte, G., Yang, M., deMello, A.J., Abell, C. and Hollfelder, F. (2009) Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assays. Lab on a Chip, 9 (5). pp. 692-698. 10.1039/b813709a.

Yang, M., Davies, G.J. and Davis, B.G. (2007) A Glycosynthase Catalyst for the Synthesis of Flavonoid Glycosides (Communication). Angewandte Chemie International Edition, 46 (21). pp. 3885-3888. 10.1002/anie.200604177.

Bolam, D.N., Roberts, S., Proctor, M.R., Turkenburg, J.P., Dodson, E.J., Martinez-Fleites, C., Yang, M., Davis, B.G., Davies, G.J. and Gilbert, H.J. (2007) The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity. Proceedings of the National Academy of Sciences of the USA, 104 (13). pp. 5336-5341. 10.1073/pnas.0607897104 .

Offen, W., Martinez-Fleites, C., Yang, M., Eng, K-L., Davis, B.G. and Davies, G.J. (2006) Structure and activity of a flavonoid 3-O-glucosyltransferase reveals the basis for plant natural product modification. EMBO Journal, 25 (6). pp. 1396-1405. 10.1038/sj.emboj.7600970 .

Yang, M., Brazier, M., Edwards, R. and Davis, B.G. (2005) High throughput mass spectrometry monitoring for multi-substrate enzymes: determining the kinetic parameters and catalytic activities of known and novel glycosyltransferases. ChemBioChem, 6 (2). pp. 346-357. 10.1002/cbic.200400100.

Yang, M., Proctor, M.R., Bolam, D.N., Errey, J.C., Field, R.A., Gilbert, H.J. and Davis, B.G. (2005) Probing the breadth of macrolide glycosyltransferases: in vitro remodeling of a polyketide antibiotic creates active bacterial uptake and enhances potency. Journal of the American Chemical Society, 127 (26). pp. 9336-9337. 10.1021/ja051482n .

Flint, J., Taylor, E., Yang, M., Bolam, D.N., Tailford, L., Martinez-Fleites, C., Dodson, E., Davis, B.G., Gilbert, H.J. and Davies, G.J. (2005) Structural dissection and high throughput screening of mannosylglycerate synthase. Nature Structural & Molecular Biology, 12 (7). pp. 608-614. 10.1038/nsmb950.

Patent

Isis Innovation Limited, UK (2006) Glycosylation of macrolide antibiotics. 2005-GB2661, 2006003456 .

This list was generated on Thu Jul 24 16:26:13 2014 BST.