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Number of items: 65.

Article

Shiu, W.K.P., Rahman, M.M., Curry, J., Stapleton, P.D., Zloh, M., Malkinson, J.P. and Gibbons, S. (2012) Antibacterial Acylphloroglucinols from Hypericum olympicum. Journal of Natural Products, 75 (3). pp. 336-343. 10.1021/np2003319.

Lalatsa, A., Lee, V.W.Y., Malkinson, J.P., Zloh, M., Schatzlein, A.G. and Uchegbu, I.F. (2012) A Prodrug Nanoparticle Approach for the Oral Delivery of a Hydrophilic Peptide, Leucine5-enkephalin, to the Brain. Molecular Pharmaceutics, 9 (6). pp. 1665-1680. 10.1021/mp300009u.

Cong, Y., Pawlisz, E., Bryant, P., Balan, S., Laurine, E., Tommasi, R., Singh, R., Dubey, S., Peciak, K., Bird, M., Sivasankar, A., Swierkosz, J., Muroni, M., Heidelberger, S., Farys, M., Khayrzad, F., Edwards, J., Badescu, G., Hodgson, I., Heise, C., Somavarapu, S., Liddell, J., Powell, K., Zloh, M., Choi, J-W., Godwin, A. and Brocchini, S. (2012) Site-Specific PEGylation at Histidine Tags. Bioconjugate Chemistry, 23 (2). pp. 248-263. 10.1021/bc200530x.

Rahman, S.S., Simovic, I., Gibbons, S. and Zloh, M. (2011) In silico screening for antibiotic escort molecules to overcome efflux. Journal of Molecular Modeling, 17 (11). pp. 2863-2872. 10.1007/s00894-011-0978-7.

Barata, T.S., Teo, I., Lalwani, S., Simanek, E., Zloh, M. and Shaunak, S. (2011) Computational design principles for bioactive dendrimer based constructs as antagonists of the TLR4-MD-2-LPS complex. Biomaterials, 32 (33). pp. 8702-8711. 10.1016/j.biomaterials.2011.07.085.

Barata, T.S., Brocchini, S., Teo, I., Shaunak, S. and Zloh, M. (2011) From sequence to 3D structure of hyperbranched molecules: application to surface modified PAMAM dendrimers. Journal of Molecular Modeling . 10.1007/s00894-011-0966-y.

Said, M.M., Gibbons, S., Moffat, A.C. and Zloh, M. (2011) Near-infrared spectroscopy (NIRS) and chemometric analysis of Malaysian and UK paracetamol tablets: a spectral database study. International Journal of Pharmaceutics, 415 (1-2). pp. 102-109. 10.1016/j.ijpharm.2011.05.057.

Barata, T.S., Teo, I., Brocchini, S., Zloh, M. and Shaunak, S. (2011) Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses. PLoS computational biology, 7 (6). e1002095. 10.1371/journal.pcbi.1002095.

Ashiru, D.A.I., Karu, K., Zloh, M., Patel, R. and Basit, A.W. (2011) Relative quantification of polyethylene glycol 400 excreted in the urine of male and female volunteers by direct injection electrospray-selected ion monitoring mass spectrometry. International Journal of Pharmaceutics, 414 (1-2). pp. 35-41. 10.1016/j.ijpharm.2011.04.061.

Barata, T.S., Shaunak, S., Teo, I., Zloh, M. and Brocchini, S. (2011) Structural studies of biologically active glycosylated polyamidoamine (PAMAM) dendrimers. Journal of Molecular Modeling, 17 (8). pp. 2051-2060. 10.1007/s00894-010-0907-1.

Moorhouse, A.D., Spiteri, C., Sharma, P., Zloh, M. and Moses, J.E. (2011) Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5. Chemical Communications, 47 (1). pp. 230-232. 10.1039/c0cc01166e.

Mkrtchyan, H., Gibbons, S., Heidelberger, S., Zloh, M. and Limaki, H.K. (2010) Purification, characterisation and identification of acidocin LCHV, an antimicrobial peptide produced by Lactobacillus acidolphilus n. v. Er. 317/402 strain Narine. International Journal of Antimicrobial Agents, 35 (3). pp. 255-260. 10.1016/j.ijantimicag.2009.11.017.

Tasdemir, D., Sanabria, D., Lauinger, I.L., Tarun, A., Herman, R., Perozzo, R., Zloh, M., Kappe, S.H., Brun, R. and Carballeira, N.M. (2010) 2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections. Bioorganic and Medicinal Chemistry, 18 (21). pp. 7475-7485. 10.1016/j.bmc.2010.08.055 .

Gibbons, S. and Zloh, M. (2010) An analysis of the 'legal high' mephedrone. Bioorganic & medicinal chemistry letters, 20 (14). pp. 4135-4139. 10.1016/j.bmcl.2010.05.065.

Antonow, D., Kaliszczak, M., Kang, G.D., Coffils, M.J., Tiberghien, A.C., Cooper, N., Barata, T.S., Heidelberger, S., James, C.H., Zloh, M., Jenkins, T.C., Reszka, A.P., Neidle, S., Guichard, S.M., Jodrell, D.I., Hartley, J.A., Howard, P.W. and Thurston, D.E. (2010) Structure−Activity Relationships of Monomeric C2-Aryl Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Antitumor Agents. Journal of Medicinal Chemistry, 53 (7). pp. 2927-2941. 10.1021/jm901722v.

Drakulic, B.J., Stavri, M., Gibbons, S., Zizak, Z.S., Verbic, T.Z., Juranic, I.O. and Zloh, M. (2009) Aryldiketo acids have antibacterial activity against MDR S. aureus strains. Structural insights based on similarity and molecular interaction fields. Chemmedchem, 4 (12). pp. 1971-1975. 10.1002/cmdc.200900273.

Bernal, P., Zloh, M. and Taylor, P.W. (2009) Disruption of D-alanyl esterification of Staphylococcus aureus cell wall teichoic acid by the beta-lactam-resistance modifier(-)-epicatechin gallate. Journal of Antimicrobial Chemotherapy, 63 (6). pp. 1156-1162. 10.1093/jac/dkp094.

Politi, M., Zloh, M., Pintado, M.E., Castro, P.M.L., Heinrich, M. and Prieto-Garcia, J.M. (2009) Direct metabolic fingerprinting of commercial herbal tinctures by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. Phytochemical Analysis, 20 (4). pp. 328-334. 10.1002/pca.1131.

Ali, F., Zakkar, M., Karu, K., Lidington, E.A., Hamdulay, S.S., Boyle, J.J., Zloh, M., Bauer, A., Haskard, D.O., Evans, P.C. and Mason, J.C. (2009) Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow. Journal of Biological Chemistry, 284 . pp. 18882-18892. 10.1074/jbc.M109.009886 .

Verbic, T.Z., Drakulic, B.J., Zloh, M. and Juranic, I.O. (2008) The effect of phenyl substituents on 13C NMR shifts and metal ions binding to 4-phenyl-2,4-dioxobutanoic acid derivatives. Letters in Organic Chemistry, 5 (8). pp. 692-699.

Smith, E.C.J., Wareham, N., Zloh, M. and Gibbons, S. (2008) 2beta-acetoxyferruginol - a new antibacterial abietane diterpend from the bark of Prumnopitys andina. Phytochemistry Letters, 1 (1). pp. 49-53. 10.1016/j.phytol.2007.12.006 .

Kontiza, I., Stavri, M., Zloh, M., Vagias, M., Gibbons, S. and Roussis, V. (2008) New metabolites with antibacterial activity from the marine angiosperm Cymodocea nodosa. Tetrahedron, 64 (8). pp. 1696-1702. 10.1016/j.tet.2007.12.007 .

Politi, M., Peschel, W., Wilson, N.D., Zloh, M., Prieto-Garcia, J.M. and Heinrich, M. (2008) Direct NMR analysis of cannabis water extracts and tinctures and semi-quantitative data on delta9-THC and delta9-THC-acid. Phytochemistry Reviews, 69 (2). pp. 562-570. 10.1016/j.phytochem.2007.07.018.

Brocchini, S., Godwin, A., Balan, S., Choi, J-W., Zloh, M. and Shaunak, S. (2008) Disulfide bridge based PEGylation of proteins. Advanced Drug Delivery Reviews, 60 (1). pp. 3-12. 10.1016/j.addr.2007.06.014.

Cevher, E., Şensoy, D., Zloh, M. and Mülazımoğlu, L. (2008) Preparation and characterisation of natamycin: γ-cyclodextrin inclusion complex and its evaluation in vaginal mucoadhesive formulations. Journal of Pharmaceutical Sciences, 97 (10). pp. 4319-4335. 10.1002/jps.21312.

Drakulić, B.J., Juranić, I.O., Erić, S. and Zloh, M. (2008) Role of complexes formation between drugs and penetration enhancers in transdermal delivery. International Journal of Pharmaceutics, 363 (1-2). pp. 40-49. 10.1016/j.ijpharm.2008.06.032.

Antonow, D., Barata, T.S., Jenkins, T.C., Parkinson, D.N., Howard, P.W., Thurston, D.E. and Zloh, M. (2008) Solution structure of a 2:1 C2-(2-naphthyl) pyrrolo[2,1-c][1,4]benzodiazepine DNA adduct: molecular basis for unexpectedly high DNA helix stabilization. Biochemistry, 47 (45). pp. 11818-11829. 10.1021/bi801225q.

Zloh, M., Bucar, F. and Gibbons, S. (2007) Quantum chemical studies on structure activity relationship of natural product polyacetylenes. Theoretical Chemistry Accounts, 117 (2). pp. 1-6. 10.1007/s00214-006-0148-7.

Zloh, M., Shaunak, S., Balan, S. and Brocchini, S. (2007) Identification and insertion of 3 carbon bridge in protein disulfide bonds. Nature Protocols, 2 (5). pp. 1070-1083. 10.1038/nprot.2007.119.

Godwin, A., Choi, J-W., Pedone, E., Shaunak, S., Brocchini, S. and Zloh, M. (2007) Molecular dynamics simulation of proteins with modified disulfide bonds. Theoretical Chemistry Accounts, 117 (2). pp. 259-263. 10.1007/s00214-006-0134-0.

Zloh, M. and Gibbons, S. (2007) The role of small molecule-small molecule interactions in overcoming biological barriers for antibacterial drug action. Theoretical Chemistry Accounts, 117 (2). pp. 231-238. 10.1007/s00214-006-0149-6.

Balan, S., Choi, J-W., Godwin, A., Teo, I., Laborde, C.M., Heidelberger, S., Zloh, M., Shaunak, S. and Brocchini, S. (2007) Site-specific PEGylation of protein disulfide bonds using a 3-carbon bridge. Bioconjugate Chemistry, 18 (1). pp. 61-76. 10.1021/bc0601471.

Verbic, T.Z., Drakulic, B.J., Zloh, M., Pecelj, J., Popovic, G. and Juranic, I.O. (2007) An LFER study of the protolytic equilibria of 4-aryl-2,4-dioxobutanoic acids in aqueous solutions. Journal of the Serbian Chemical Society, 72 (12). pp. 1201-1216. 10.2298/JSC0712201V.

Shaunak, S., Godwin, A., Choi, J-W., Balan, S., Pedone, E., Vijayarangam, D., Heidelberger, S., Teo, I., Zloh, M. and Brocchini, S. (2006) Site-specific PEGylation of native disulfide bonds in therapeutic proteins. Nature Chemical Biology, 2 . pp. 312-313. 10.1038/nchembio786.

Yalcin, F.N., Ersoz, T., Donmetz, A.A., Stavri, M., Zloh, M. and Gibbons, S. (2006) Amanicadol, a pimarane type diterpene from Phlomis anamica Vierch. Zeitschrift fur Naturforschung, 61b (11). pp. 1433-1436.

Brocchini, S., Balan, S., Zloh, M. and Shaunak, S. (2006) Efficient PEGylation of proteins by bis-thiol alkylation of native disulfide bonds. Nature Protocols, 1 (5). pp. 2241-2252. 10.1038/nprot.2006.346.

Brocchini, S., Balan, S., Godwin, A., Choi, J-W., Zloh, M. and Shaunak, S. (2006) PEGylation of native disulfide bonds in proteins. Nature Protocols, 1 (5). pp. 2241-2252. 10.1038/nprot.2006.346.

Brocchini, S., Balan, S., Zloh, M. and Shaunak, S. (2006) PEGylation of proteins by bis-thiol alkylation of native disulfide bonds. Nature Protocols, 1 . pp. 2241-2252. 10.1038/nprot.2006.346.

Njoh, K.L., Patterson, L.H., Zloh, M., Wiltshire, M., Fisher, J., Ameer-beg, S.M., Bai, Y., Mathews, D., Errington, Rachel J. and Smith, P.J. (2006) Spectral analysis of the DNA targeting bisalkylaminoanthraquinone DRAQ5 in intact living cells. Cytometry A, 69 (8). pp. 804-814. 10.1002/cyto.a.20308.

Pors, K., Shnyder, S.D., Teesdale-Spittle, P.H., Hartley, J.A., Zloh, M., Searcey, M. and Patterson, L.H. (2006) Synthesis of DNA-directed pyrrolidinyl and piperidinyl confined alkylating chloroalkylaminoanthraquinones: potential for development of tumor-selective N-oxides. Journal of Medicinal Chemistry, 49 (24). pp. 7013-7023. 10.1021/jm0608154.

Errington, Rachel J., Ameer-beg, S.M., Vojnovic, B., Patterson, L.H., Zloh, M. and Smith, P.J. (2005) Advanced microscopy solutions for monitoring the kinetics and dynamics of drug-DNA targeting in living cells. Advanced Drug Delivery Reviews, 57 . pp. 153-167. 10.1016/j.addr.2004.05.005 .

Malkinson, J.P., Anim, M., Zloh, M. and Searcey, M. (2005) Efficient solid-phase-based total synthesis of the bisintercalator TANDEM. Journal of Organic Chemistry, 70 (19). pp. 7654-7661. 10.1021/jo050959a.

Zloh, M., Ramaswamy, C., Sakthivel, T., Wilderspin, A.F. and Florence, A.T. (2005) Investigation of the association and flexibility of cationic lipidic peptide dendrons by NMR spectroscopy. Magnetic Resonance in Chemistry, 43 . pp. 47-52. 10.1002/mrc.1508.

Smith, E.C.J., Williamson, E.M., Zloh, M. and Gibbons, S. (2005) Isopimaric acid from Pinus nigra shows activity against multi-drug-resistant and EMRSA strains of staphylococcus aureus. Phytotherapy Research, 19 . pp. 538-542. 10.1002/ptr.1711.

Rankin, S., Reszka, A.P., Huppert, J., Zloh, M., Parkinson, G.N., Todd, A.K., Ladame, S., Balasubramanian, S. and Neidle, S. (2005) Putative DNA quadruplex formation within the human c-kit oncogene. Journal of the American Chemical Society, 127 . pp. 10584-10589. 10.1021/ja050823u.

Zloh, M., Kaatz, G.W. and Gibbons, S. (2004) Inhibitors of multidrug resistance have affinity for MDR substrates. Bioorganic and Medicinal Chemistry Letters, 14 . pp. 881-885. 10.1016/j.bmcl.2003.12.015 .

Zloh, M. and Gibbons, S. (2004) Molecular similarity of MDR inhibitors. International Journal of Molecular Sciences, 5 . pp. 48-55.

Zloh, M., Dinand, E. and Brocchini, S. (2003) Aconityl-derived polymers for biomedical applications: modeling study of cis-trans isomerisation. Theoretical Chemistry Accounts, 109 . pp. 206-212. 10.1007/s00214-002-0403-5.

Zloh, M., Esposito, D. and Gibbons, S. (2003) Helical net plots and lipid favourable surface mapping of transmembrane helices of integral membrane proteins:aids to structure determination of integral membrane proteins. Internet Journal of Chemistry, 6 (2).

Malkinson, J.P., Zloh, M., Kadom, M., Errington, R., Smith, P.J. and Searcey, M. (2003) Solid phase synthesis of the cyclic peptide portion of chlorofusin, an inhibitor of p53-mdm2 interactions. Organic Letters, 5 . pp. 5051-5054. 10.1021/ol0360849.

Dinand, E., Zloh, M. and Brocchini, S. (2002) Competitive reactions during amine addition to cis-aconityl anhydride. Australian Journal of Chemistry, 55 . pp. 467-474. 10.1071/CH02092.

Zloh, M., Esposito, D. and Gibbons, W.A. (2001) Docking of transmembrane helices into four helix bundles in the high affitiy IgE receptor. Internet Journal of Chemistry, 4 (8).

Zloh, M., Dinand, E. and Brocchini, S. (2001) Molecular modelling study of a degradable element for biomedical polymers. Internet Journal of Chemistry, 4 (9).

Zloh, M., Esposito, D. and Gibbons, W.A. (2000) Spectroscopy-Based Modelling of the 3D Structure of the β Subunit of the High Affinity IgE Receptor. Molecular Simulation, 24 (4-6). pp. 421-447. 10.1080/08927020008022386.

Bonzom, P.M., Nicolaou, A., Zloh, M., Baldeo, W. and Gibbons, W.A. (1999) NMR lipid profile of Agaricus bisporus. Phytochemistry, 50 (8). pp. 1311-1321. 10.1016/S0031-9422(98)00703-1.

Esposito, D., Zloh, M. and Gibbons, W.A. (1998) Molecular modelling of the IgE receptor loops-lipid interaction. Biochemical Society Transactions, 26 (1). S35.

Zloh, M., Esposito, D. and Gibbons, W.A. (1998) NMR studies of the extracellular loop of the beta subunit of the high affinity IgE receptor. Biochemical Society Transactions, 26 (1). S34.

Aleksić, A.D., Zloh, M. and Juranić, I.O. (1994) Mechanism of excitation and emission of papaverine molecule: fluorescence polarization spectroscopy study and MO calculation of transition moments. Journal of Luminescence, 59 (1-2). pp. 27-32. 10.1016/0022-2313(94)90018-3.

Zloh, M., Anderson, G., Clark-Lewis, I., Thomas, R., Benedetti, E., Toth, I. and Gibbons, W.A. (1994) N.m.r. studies of the cytoplasmic C-terminal beta-subunit domain of the high-affinity IgE receptor. Biochemical Society Transactions, 22 (4). pp. 1027-1029.

Zloh, M., Anderson, G., Clark-Lewis, I., Nicolau, A., Thomas, R., Toth, I. and Gibbons, W.A. (1994) Spectroscopic and conformational studies of the C-terminal cytoplasmic beta subunit 46-peptide of the high affinity IgE receptor. Biochemical Society Transactions, 22 (4). 450S.

Book Section

Kerenza, L., Njoh, Laurence H., Pors, K., Zloh, M., Ameer-beg, S.M., Summers, Huw, Matthews, Daniel, Errington, Rachel J. and Smith, Paul J. (2006) Screening far red probes for use on optical biochip devices. In: Imaging, Manipulation and Analysis of Biomolecules, Cells and Tissues IV. Proc. SPIE, pp. 122-132.

Zloh, M., Esposito, D. and Gibbons, W.A. (2001) Docking of transmembrane helices into four helix bundles in the high affinity IgE receptor. In: Peptides, The Wave of the Future. Kluwer Academic Publishers, pp. 842-843. ISBN 1402004737.

Zloh, M., Esposito, D. and Gibbons, W.A. (2001) Helical net plots and surface lipophilicity mapping of transmembrane helices of integral membrane proteins: aids to 3d structure determination of integral membrane proteins. In: Peptides, The Wave of the Future. Kluwer Academic Publishers, pp. 843-844. ISBN 1402004737.

Conference or Workshop Item

Said, M.M., Gibbons, S. and Zloh, M. (2009) Qualitative comparison of Malaysian and UK paracetamol tablets by near-infra red. In: British Pharmaceutical Conference: Quality and safety: new vision, old values , 6-9 September 2009, Manchester, UK. DOI 10.1211/002235709789037053.

Said, M.M., Gibbons, S. and Zloh, M. (2009) The role of complex formation between inhibitors and substrates of efflux pumps in bacteria. In: British Pharmaceutical Conference, 6th - 9th September 2009, Manchester, UK.

This list was generated on Thu Oct 23 15:27:08 2014 BST.