Items where year is 1995

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Number of items: 54.

A

Adie, E .J., Thomas, P.H., Munday, M. and Clegg, R.A. (1995) Subcellular targeting of recombinant and mammalian C alpha subunits of cAMP-dependent protein kinase. Biochemical Society Transactions, 23 (3). 451S.

B

Blackett, P.M. and Buckton, G. (1995) A Microcalorimetric Investigation of the Interaction of Surfactants with Crystalline and Partially Crystalline Salbutamol Sulphate in a Model Inhalation Aerosol System. Pharmaceutical Research, 12 (11). p. 1689. 10.1023/A:1016257504115.

Blackett, P.M. and Buckton, G. (1995) A microcalorimetric study of surfactant aggregation and surfactant-drug interaction in a model inhalation aerosol system. International Journal of Pharmaceutics, 125 (1). pp. 133-139. 10.1016/0378-5173(95)00132-3.

Buckton, G. (1995) Applications of isothermal microcalorimetry in the pharmaceutical sciences. Thermochimica Acta, 248 . pp. 117-129. 10.1016/0040-6031(94)01894-M.

Bhandal, N.S., Ramsey, R.L., Harvey, R.J., Darlison, M.G. and Usherwood, P.N.R. (1995) Channel gating in the absence of agonist by a homooligomeric molluscan GABA receptor expressed inXenopus oocytes from a cloned cDNA. Invertebrate Neuroscience, 1 (3). pp. 267-272. 10.1007/BF02211028.

Britton, P., Whitton, P.S. and Bowery, N.G. (1995) Effect of tetanus toxin on basal and evoked release of 5-hydroxytryptamine and dopamine in rat hippocampus in vivo. Brain Research, 673 (2). pp. 331-334. 10.1016/0006-8993(94)01458-T.

Biggs, C.S., Fowler, L.J., Whitton, P.S. and Starr, M.S. (1995) Impulse-dependent and tetrodotoxin-sensitive release of GABA in the rat's substantia nigra measured by microdialysis. Brain Research, 684 (2). pp. 172-178. 10.1016/0006-8993(95)00281-T.

Buckton, G., Darcy, P. and McCarthy, D. (1995) The extent of errors associated with contact angles 3. The influence of surface roughness effects on angles measured using a Wilhelmy plate technique for powders. Colloids and Surfaces A Physicochemical and Engineering Aspects, 95 (1). p. 27. 10.1016/0927-7757(94)03001-G.

Buckton, G. (1995) The influence of additives on the recrystallisation of amorphous spray dried lactose. International Journal of Pharmaceutics, 121 (1). pp. 81-87. 10.1016/0378-5173(95)00009-8.

Buckton, G. and Darcy, P. (1995) The use of gravimetric studies to assess the degree of crystallinity of predominantly crystalline powders. International Journal of Pharmaceutics, 123 (2). pp. 265-271. 10.1016/0378-5173(95)00083-U.

Buckton, G., Darcy, P., Greenleaf, D. and Holbrook, P. (1995) The use of isothermal microcalorimetry in the study of changes in crystallinity of spray-dried salbutamol sulphate. International Journal of Pharmaceutics, 116 (1). pp. 113-118. 10.1016/0378-5173(94)00322-V.

Buckton, G., Darcy, P. and Mackellar, A.J. (1995) The use of isothermal microcalorimetry in the study of small degrees of amorphous content of powders. International Journal of Pharmaceutics, 117 (2). pp. 253-256. 10.1016/0378-5173(94)00421-Z.

C

Chazot, P.L., Cik, M. and Stephenson, F.A. (1995) An investigation into the role of N-glycosylation in the functional expression of a recombinant heteromeric NMDA receptor. Molecular Membrane Biology, 12 (4). pp. 331-337.

Cossens, M.J., Davies, G., Bose, D. and Horne, R. (1995) Factors influencing the choice of drug therapy in primary and secondary health care. International Journal of Pharmacy Practice, 3 (4). pp. 213-218. 10.1111/j.2042-7174.1995.tb00821.x.

Coombes, I., Davies, G. and Horne, R. (1995) Succeeding with failures. Pharmaceutical Journal, 254 . p. 423.

D

Dean, B., Allan, E.L., Barber, N. and Barker, K.N. (1995) Comparison of medication errors in a UK and a US hospital. American Journal of Health-System Pharmacy, 52 . pp. 2543-2549.

Deuchars, J. and Thomson, A.M. (1995) Innervation of burst firing spiny interneurons by pyramidal cells in deep layers of rat somatomotor cortex: paired intracellular recordings with biocytin filling. Neuroscience, 69 (3). pp. 739-755. 10.1016/0306-4522(95)00288-T.

Deuchars, J. and Thomson, A.M. (1995) Single axon fast inhibitory postsynaptic potentials elicited by a sparsely spiny interneuron in rat neocortex. Neuroscience, 65 (4). pp. 935-942. 10.1016/0306-4522(95)00020-J.

da Cruz Fresco, P., Shacker, F. and Kortenkamp, A. (1995) The reductive conversion of chromium (VI) by ascorbate gives rise to apurinic/apyrimidinic sites in isolated DNA. Chemical Research in Toxicology, 8 (6). pp. 884-890. 10.1021/tx00048a009.

G

Geiss, F., Heinrich, M., Hunkler, D. and Rimpler, H. (1995) Proanthocyanidins with ( + )-epicatechin units from Byrsonima crassifolia bark. Phytochemistry, 39 (3). pp. 635-643. 10.1016/0031-9422(94)00934-L.

Gessler, M.C., Tanner, M., Chollet, J., Nkunya, M.H.H. and Heinrich, M. (1995) Tanzanian medicinal plants used traditionally for the treatment of malaria:In vivo antimalarial andin vitro cytotoxic activities. Phytotherapy Research, 9 (7). pp. 504-508.

Gessler, M.C., Msuya, D.E., Nkunya, M.H.H., Schär, A., Heinrich, M. and Tanner, M. (1995) Traditional healers in Tanzania: sociocultural profile and three short portraits. Journal of Ethnopharmacology, 48 (3). pp. 145-160. 10.1016/0378-8741(95)01295-O.

Gessler, M.C., Msuya, D.E., Nkunya, M.H.H., Schär, A., Heinrich, M. and Tanner, M. (1995) Traditional healers in Tanzania: the perception of malaria and its causes. Journal of Ethnopharmacology, 48 (3). pp. 119-130. 10.1016/0378-8741(95)01294-N.

Gessler, M.C., Msuya, D.E., Nkunya, M.H.H., Mwasumbi, L.B., Schär, A., Heinrich, M. and Tanner, M. (1995) Traditional healers in Tanzania: the treatment of malaria with plant remedies. Journal of Ethnopharmacology, 48 (3). p. 131. 10.1016/0378-8741(95)01293-M.

H

Hör, M., Rimpler, H. and Heinrich, M. (1995) Inhibition of Intestinal Chloride Secretion by Proanthocyanidins fromGuazuma ulmifolia. Planta Medica, 61 (03). p. 208. 10.1055/s-2006-958057.

Harris, N.C. and Constanti, A. (1995) Mechanism of block by ZD 7288 of the hyperpolarization-activated inward rectifying current in guinea pig substantia nigra neurons in vitro. Journal of Neurophysiology, 74 (6). pp. 2366-2378.

Hemingway, C.J., Tey, K.K. and Munday, M. (1995) Short-term inhibition of fatty acid and cholesterol biosynthesis by the lipid-lowering drug gemfibrozil in primary rat hepatocyte cultures and rat liver in vivo. Biochemical Society Transactions, 23 (3). 496S.

Hafiz, F., Thurston, D.E., Carr, A.M. and Jones, R.W. (1995) The cytotoxicity of anthramycin to mutants of Schizosaccharomyces pombe deficient in DNA damage responses. Biochemical Society Transactions, 23 (2). 331S.

Harvey, R.J., Lobron, C., Reinhardt-Maelicke , S., Maelicke, A. and Darlison, M.G. (1995) The embryonal carcinoma cell line PCC7-S-AzaR1 (clone 1009) expresses a functional GABAA receptor comprising the [alpha]5, [beta]3 and [gamma]3 subunits: 21.2.(Poster). Behavioural Pharmacology, 6 . pp. 119-120.

K

Kuhnt, M., Pröbstle, A., Rimpler, H., Bauer, R. and Heinrich, M. (1995) Biological and pharmacological activities and further constituents of Hyptis verticillata. Planta Medica, 61 (3). pp. 227-232. 10.1055/s-2006-958061.

M

Malcangio, M., Libri, V., Teoh, H.L., Constanti, A. and Bowery, N.G. (1995) Chronic (-)baclofen or CGP 36742 alters GABAB receptor sensitivity in rat brain and spinal cord. Neuroreport, 6 (2). pp. 399-403.

Mall, S, Buckton, G., Gregori, T. and Rawlins, D.A. (1995) Investigation of a relationship between surface energy terms and the thermodynamics of transfer of drugs into sodium dodecyl sulfate micelles. Journal of Physical Chemistry B, 99 (20). pp. 8356-8361. 10.1021/j100020a071.

Maione, S., Biggs, C.S., Rossi, F., Fowler, L.J. and Whitton, P.S. (1995) α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors modulate dopamine release in rat hippocampus and striatum. Neuroscience Letters, 193 (3). pp. 181-184. 10.1016/0304-3940(95)11695-S.

P

Poyner, E., Alpar, H.O., Almeida, A.J., Gamble, M.D. and Brown, M.R.W. (1995) A comparative study on the pulmonary delivery of tobramycin encapsulated into liposomes and PLA microspheres following intravenous and endotracheal delivery. Journal of Controlled Release, 35 (1). pp. 41-48. 10.1016/0168-3659(95)00017-3.

Pinto, J.F., Buckton, G. and Newton, J.M. (1995) A relationship between surface free energy and polarity data and some physical properties of spheroids. International Journal of Pharmaceutics, 118 (1). pp. 95-101. 10.1016/0378-5173(94)00357-B.

Pollard, S., Thompson, C.L. and Stephenson, F.A. (1995) Quantitative characterization of alpha 6 and alpha 1 alpha 6 subunit-containing native gamma-aminobutyric acidA receptors of adult rat cerebellum demonstrates two alpha subunits per receptor oligomer. Journal of Biological Chemistry, 270 (36). pp. 21285-21290. 10.1074/jbc.270.36.21285.

R

Rillosi, M. and Buckton, G. (1995) Modelling mucoadhesion by use of surface energy terms obtained by the Lewis acid-Lewis base approach. International Journal of Pharmaceutics, 117 (1). pp. 75-84. 10.1016/0378-5173(94)00319-Z.

Rillosi, M. and Buckton, G. (1995) Modelling Mucoadhesion by Use of Surface Energy Terms Obtained from the Lewis Acid–Lewis Base Approach. II. Studies on Anionic, Cationic, and Unionisable Polymers. Pharmaceutical Research, 12 (5). pp. 669-675. 10.1023/A:1016299223369.

Richter-Landsberg, C. and Heinrich, M. (1995) S-100 immunoreactivity in rat brain glial cultures is associated with both astrocytes and oligodendrocytes. Journal of Neuroscience Research, 42 (5). pp. 657-665. 10.1002/jnr.490420508.

S

Stapleton, P.D., Shannon, K.P. and Phillips, I. (1995) DNA sequence differences of ampD mutants of Citrobacter freundii. Antimicrobial Agents and Chemotherapy, 39 (11). pp. 2494-2498.

Stapleton, P.D., Wu, P.J., King, A., Shannon, K.P., French, G.L. and Phillips, I. (1995) Incidence and mechanisms of resistance to the combination of amoxicillin and clavulanic acid in Escherichia coli. Antimicrobial Agents and Chemotherapy, 39 (11). pp. 2478-2483.

Segieth, J., Getting, S.J., Biggs, C.S. and Whitton, P.S. (1995) Nitric oxide regulates excitatory amino acid release in a biphasic manner in freely moving rats. Neuroscience Letters, 200 (2). pp. 101-104. 10.1016/0304-3940(95)12088-L.

Sciancalepore, M. and Constanti, A. (1995) Patch-clamp study of neurones in rat olfactory cortex slices: properties of a slow post-stimulus afterdepolarizing current (IADP). Neuroreport, 6 (18). pp. 2489-2494.

Stapleton, P.D., Shannon, K.P. and Phillips, I. (1995) The ability of beta-lactam antibiotics to select mutants with derepressed beta-lactamase synthesis from Citrobacter freundii. Journal of Antimicrobial Chemotherapy, 36 (3). pp. 483-496. 10.1093/jac/36.3.483.

Stephenson, F.A. (1995) The GABAA receptors. Biochemical Journal, 310 ( Pt 1) . pp. 1-9.

Smith, L.A., Amar, M., Harvey, R.J., Darlison, M.G., Earley, F.G.P., Beadle, D.J., King, L.A. and Bermudez, I. (1995) The Production of a Stably Transformed Insect Cell Line Expressing An Invertebrate GABAAReceptor β-Subunit. Journal of Receptors and Signal Transduction, 15 (1-4). pp. 33-41. 10.3109/10799899509045205.

Sheridan, P.L., Buckton, G. and Storey, D.E (1995) The use of molecular orbital indices to predict the surface properties of pharmaceutical powders. International Journal of Pharmaceutics, 125 (1). pp. 141-149. 10.1016/0378-5173(95)00143-7.

T

Thomas, P.H., Adie, E.J., Clegg, R.A. and Munday, M. (1995) Autophosphorylation of cAMP-dependent protein kinase catalytic subunit. Biochemical Society Transactions, 23 (3). 500S.

Toomey, C.M., Welham, K.J. and Munday, M. (1995) Identification of an endogenous inhibitor of AMP-activated protein kinase. Biochemical Society Transactions, 23 (1). 142S.

Toomey, C.M., Flinn, N., van der Walle, C., Toth, I. and Munday, M. (1995) Peptide substrates for AMP-activated protein kinase. Biochemical Society Transactions, 23 (1). 141S.

Thomson, A.M., West, D.C. and Deuchars, J. (1995) Properties of single axon excitatory postsynaptic potentials elicited in spiny interneurons by action potentials in pyramidal neurons in slices of rat neocortex. Neuroscience, 69 (3). pp. 727-738. 10.1016/0306-4522(95)00287-S.

U

Uchegbu, I.F., Double, J.A., Turton, J.A. and Florence, A.T. (1995) Distrubution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monosterate (Span 60) niosomes in the mouse. Pharmaceutical Research, 12 (7). pp. 1091-1024. 10.1023/A:1016210515134.

W

Webster, M-T., Groome, N., Francis, P.T., Pearce, B.R., Sherriff, F.E., Thinakaran, G., Felsenstein, K.M., Wasco, W., Tanzi, R.E. and Bowen, D.M. (1995) A novel protein, amyloid precursor-like protein 2, is present in human brain, cerebrospinal fluid and conditioned media. Biochemical Journal, 310 (1). pp. 95-99.

Wilson, S.C., Howard, P.W. and Thurston, D.E. (1995) Design and synthesis of a novel epoxide-containing pyrrolo[2,1-c][1,4]benzodiazepine (PBD) via a new cyclization procedure. Tetrahedron Letters, 36 (35). pp. 6333-6336. 10.1016/0040-4039(95)01224-6.

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