Items where year is 2012

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Number of items: 62.


Al-Jamal, K.T., Al-Jamal, W.T., Kostarelos, K., Turton, J.A. and Florence, A.T. (2012) Anti-angiogenic poly-L-lysine dendrimer binds heparin and neutralizes its activity. Results in Pharma Sciences, 2 . pp. 9-15. 10.1016/j.rinphs.2011.12.002.

Almeida e Sousa, L., Beezer, A.E., Hansen, L.D., Clapham, D., Connor, J.A. and Gaisford, S. (2012) Calorimetric Determination of Rate Constants and Enthalpy Changes for Zero-Order Reactions. Journal of Physical Chemistry B, 116 (22). pp. 6356-6360. 10.1021/jp302933f.

Abuirmeileh, A., Harkavyi, A., Rampersaud, N., Lever, R., Tadross, J.A., Bloom, S.R. and Whitton, P.S. (2012) Exendin-4 treatment enhances L-DOPA evoked release of striatal dopamine and decreases dyskinetic movements in the 6-hydoxydopamine lesioned rat. Journal of Pharmacy and Pharmacology, 64 (5). pp. 637-643. /10.1111/j.2042-7158.2011.01394.x.

Anderson, C., Bates, I., Brock, T.P., Brown, A.N., Bruno, A., Futter, B., Rennie, T. and Rouse, M.J. (2012) Needs-Based Education in the Context of Globalization. American Journal of Pharmaceutical Education, 76 (4). p. 56. 10.5688/ajpe76456.


Baud, M.G.J., Leiser, T., Haus, P., Samlal, S., Wong, A.C., Wood, R.J., Petrucci, V., Gunaratnam, M., Hughes, S.M., Buluwela, L., Turlais, F., Neidle, S., Meyer-Almes, F-J., White, A.J.P. and Fuchter, M.J. (2012) Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets. Journal of Medicinal Chemistry, 55 (4). pp. 1731-1750. 10.1021/jm2016182.

Brucoli, F., Natoli, A., Marimuthu, P., Borrello, M.T., Stapleton, P.D., Gibbons, S. and Schatzlein, A.G. (2012) Efficient synthesis and biological evaluation of proximicins A, B and C. Bioorganic and Medicinal Chemistry, 20 (6). pp. 2019-2024. 10.1016/j.bmc.2012.01.043.

Burnett, S., Franklin, B.D., Moorthy, K., Cooke, M.W. and Vincent, C. (2012) How reliable are clinical systems in the UK NHS? A study of seven NHS organisations. BMJ Quality & Safety . 10.1136/bmjqs-2011-000442.

Booker, A., Johnston, D. and Heinrich, M. (2012) Value chains of herbal medicines - research needs and key challenges in the context of ethnopharmacology. Journal of Ethnopharmacology . 10.1016/j.jep.2012.01.039.


Cousins, S.L. and Stephenson, F.A. (2012) Identification of N-Methyl-D-aspartic Acid (NMDA) Receptor Subtype-specific Binding Sites That Mediate Direct Interactions with Scaffold Protein PSD-95. Journal of Biological Chemistry, 287 (16). pp. 13465-13476. 10.1074/jbc.M111.292862.

Chen, K-H., Mueannoom, W., Gaisford, S. and Kett, V.L. (2012) Investigation into the effect of varying l-leucine concentration on the product characteristics of spray-dried liposome powders. Journal of Pharmacy and Pharmacology . 10.1111/j.2042-7158.2012.01521.x.

Campbell, N.H., Karim, N.H.A., Parkinson, G.N., Gunaratnam, M., Petrucci, V., Todd, A.K., Vilar, R. and Neidle, S. (2012) Molecular Basis of Structure–Activity Relationships between Salphen Metal Complexes and Human Telomeric DNA Quadruplexes. Journal of Medicinal Chemistry, 55 (1). pp. 209-222. 10.1021/jm201140v.

Cong, Y., Pawlisz, E., Bryant, P., Balan, S., Laurine, E., Tommasi, R., Singh, R., Dubey, S., Peciak, K., Bird, M., Sivasankar, A., Swierkosz, J., Muroni, M., Heidelberger, S., Farys, M., Khayrzad, F., Edwards, J., Badescu, G., Hodgson, I., Heise, C., Somavarapu, S., Liddell, J., Powell, K., Zloh, M., Choi, J-W., Godwin, A. and Brocchini, S. (2012) Site-Specific PEGylation at Histidine Tags. Bioconjugate Chemistry, 23 (2). pp. 248-263. 10.1021/bc200530x.

Collie, G.W., Promontorio, R., Hampel, S.M., Micco, M., Neidle, S. and Parkinson, G.N. (2012) Structural Basis for Telomeric G-Quadruplex Targeting by Naphthalene Diimide Ligands. Journal of the American Chemical Society, 134 (5). pp. 2723-2731. 10.1021/ja2102423.


Davies, J.E., Neidle, S. and Taylor, D.G. (2012) Developing and paying for medicines for orphan indications in oncology: utilitarian regulation vs equitable care? British Journal of Cancer, 106 (1). pp. 14-17. 10.1038/bjc.2011.544.

Dürüst, Y., Karakuş, H., Kaiser, M. and Tasdemir, D. (2012) Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles. European Journal of Medicinal Chemistry, 48 . pp. 296-304. 10.1016/j.ejmech.2011.12.028.


Franklin, B.D., Shebl, N.A. and Barber, N. (2012) Failure mode and effects analysis: too little for too much? BMJ Quality & Safety, 23rd March . 10.1136/bmjqs-2011-000723.

Falodun, A., Sheng-Xiang, Q., Parkinson, G.N. and Gibbons, S. (2012) Isolation and characterization of a new anticancer diterpenoid from Jatropha gossypifolia. Pharmaceutical Chemistry Journal, 45 (10). pp. 636-639. 10.1007/s11094-012-0693-4.

Franklin, B.D., Rosa, M.B., Miller, G. and Jacklin, A. (2012) The evaluation of a novel model of providing ward pharmacy services. International Journal of Clinical Pharmacy . 10.1007/s11096-012-9650-2.


Gill, J.L., Tsai, K.L., Krey, C., Noorai, R.E., Vanbellinghen, J-F., Garosi, L., Shelton, G.D., Clark, L.A. and Harvey, R.J. (2012) A canine BCAN microdeletion associated with episodic falling syndrome. Neurobiology of Disease, 45 (1). pp. 130-136. 10.1016/j.nbd.2011.07.014.

Gibbons, S. (2012) An Introduction to Planar Chromatography and Its Application to Natural Products Isolation. Methods in Molecular Biology (Clifton, N.J.), 864 . pp. 117-153. 10.1007/978-1-61779-624-1_6.

Gibbons, S. (2012) ‘Legal Highs’ – novel and emerging psychoactive drugs: a chemical overview for the toxicologist. Clinical Toxicology, 50 (1). pp. 15-24. 10.3109/15563650.2011.645952.

Gaisford, S. (2012) Isothermal microcalorimetry for quantifying amorphous content in processed pharmaceuticals. Advanced Drug Delivery Reviews, 64 (5). pp. 431-439.

Garrett, N.L., Lalatsa, A., Begley, D., Mihoreanu, L., Uchegbu, I.F., Schatzlein, A.G. and Moger, J. (2012) Label-free imaging of polymeric nanomedicines using coherent anti-stokes Raman scattering microscopy. Journal of Raman Spectroscopy, 43 (5). pp. 681-688. 10.1002/jrs.3170.

González-Aramundiz, J.V., Lozano, M.V., Sousa-Herves, A., Fernandez-Megia, E. and Csaba, N. (2012) Polypeptides and polyaminoacids in drug delivery. Expert Opinion on Drug Delivery, 9 (2). pp. 183-201. 10.1517/17425247.2012.647906.

Gaisford, S. (2012) Thermal analysis and calorimetry. Advanced Drug Delivery Reviews, 64 (5). p. 383. 10.1016/j.addr.2012.02.010.


Heinrich, M., Dhanji, T. and Casselman, I. (2012) Açaí (Euterpe oleracea Mart.). Zeitschrift für Phytotherapie, 33 .

Hancock, R., Bertrand, H.C., Tsujita, T., Naz, S., El-Bakry, A., Laoruchupong, J., Hayes, J.D. and Wells, G. (2012) Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction. Free Radical Biology and Medicine, 52 (2). pp. 444-451. 10.1016/j.freeradbiomed.2011.10.486.

Hancock, R., Bertrand, H.C., Tsujita, T., Naz, S., El-Bakry, A., Laoruchupong, J., Hayes, J.D. and Wells, G. (2012) Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction. Free Radical Biology and Medicine, 52 (2). pp. 444-451. 10.1016/j.freeradbiomed.2011.10.486.

Heinrich, M. and Verpoorte, R. (2012) Statistical tools in ethnopharmacology. Journal of Ethnopharmacology, 139 (3). pp. 691-692. 10.1016/j.jep.2011.09.022.


Innocent, N., Cousins, S.L. and Stephenson, F.A. (2012) NMDA receptor/amyloid precursor protein interactions: A comparison between wild-type and amyloid precursor protein mutations associated with familial Alzheimer's disease. Neuroscience Letters, 515 (2). pp. 131-136. 10.1016/j.neulet.2012.03.029.


James, V.M., Gill, J.L., Topf, M. and Harvey, R.J. (2012) Molecular mechanisms of glycine transporter GlyT2 mutations in startle disease. Biological Chemistry, 393 (4). pp. 283-289. 10.1515/bc-2011-232.

Jones, B.E., Basit, A.W. and Tuleu, C. (2012) The disintegration behaviour of capsules in fed subjects: A comparison of hypromellose (carrageenan) capsules and standard gelatin capsules. International Journal of Pharmaceutics, 424 (1-2). pp. 40-43. /10.1016/j.ijpharm.2011.12.034.


Ke, P., Hasegawa, S., Al-Obaidi, H. and Buckton, G. (2012) Investigation of preparation methods on surface/bulk structural relaxation and glass fragility of amorphous solid dispersions. International Journal of Pharmaceutics, 422 (1-2). p. 170. 10.1016/j.ijpharm.2011.10.047.


Lalatsa, A., Lee, V.W.Y., Malkinson, J.P., Zloh, M., Schatzlein, A.G. and Uchegbu, I.F. (2012) A Prodrug Nanoparticle Approach for the Oral Delivery of a Hydrophilic Peptide, Leucine5-enkephalin, to the Brain. Molecular Pharmaceutics, 9 (6). pp. 1665-1680. 10.1021/mp300009u.

Liu, Y., Servant, A., Guy, O.J., Al-Jamal, K.T., Williams, P.R., Hawkins, K.M. and Kostarelos, K. (2012) An electric-field responsive microsystem for controllable miniaturised drug delivery applications. Sensors and Actuators B: Chemical . 10.1016/j.snb.2011.12.069. (In Press)

Lever, R. and Page, C.P. (2012) Non-anticoagulant Effects of Heparin: An Overview. In: Heparin - A Century of Progress. Handbook of Experimental Pharmacology (207). Springer, pp. 281-305. 10.1007/978-3-642-23056-1_12.

Lepee, C., Klaber, R.E., Benn, J., Fletcher, P.J., Cartoos, P-J., Jacklin, A. and Franklin, B.D. (2012) The use of a consultant-led ward round checklist to improve paediatric prescribing: An interrupted time series study Carole Lépée, Robert E. Klaber, Jonathan Benn, Penny J. Fletcher, Pieter-Jan Cortoos, Ann Jacklin and Bryony Dean Franklin. European Journal of Pediatrics . 10.1007/s00431-012-1751-3Online First™.

Lacerda, L., Russier, J., Pastorin, G., Herrero, M.A., Venturelli, E., Dumortier, H., Al-Jamal, K.T., Prato, M., Kostarelos, K. and Bianco, A. (2012) Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes. Biomaterials, 33 (11). pp. 3334-3343. 10.1016/j.biomaterials.2012.01.024.


Moger, J., Garrett, N.L., Begley, D., Mihoreanu, L., Lalatsa, A., Lozano, M.V., Mazza, M., Schatzlein, A.G. and Uchegbu, I.F. (2012) Imaging cortical vasculature with stimulated Raman scattering and two-photon photothermal lensing microscopy. Journal of Raman Spectroscopy, 43 (5). pp. 668-674. 10.1002/jrs.3156.

Murdan, S., Poojary, C., Patel, D.R., Fernandes, J., Haman, A., Saundh, P.S. and Sheikh, Z. (2012) In vivo measurement of the surface energy of human fingernail plates. International Journal of Cosmetic Science, 34 (3). pp. 257-262. 10.1111/j.1468-2494.2012.00711.x.

Mercer, A., Eastlake, K., Trigg, H. and Thomson, A.M. (2012) Local circuitry involving parvalbumin-positive basket cells in the CA2 region of the hippocampus. Hippocampus, 22 (1). pp. 43-56. 10.1002/hipo.20841.

Mercer, A., Botcher, N.A., Eastlake, K. and Thomson, A.M. (2012) SP-SR interneurones: A novel class of neurones of the CA2 region of the hippocampus. Hippocampus . 10.1002/hipo.22010.

Mugglestone, C.J., Mariz, S. and Lane, M.E. (2012) The development and registration of topical pharmaceuticals. International Journal of Pharmaceutics . 10.1016/j.ijpharm.2012.03.052. (In Press)

Murdan, S. (2012) The Nail: Anatomy, Physiology, Diseases and Treatment. In: Topical Nail Products and Ungual Drug Delivery. CRC Press. ISBN 9781439811290. (In Press)

Mueannoom, W., Srisongphan, A., Taylor, K.M.G., Hauschild, S. and Gaisford, S. (2012) Thermal ink-jet spray freeze-drying for preparation of excipient-free salbutamol sulphate for inhalation. European Journal of Pharmaceutics and Biopharmaceutics, 80 (1). pp. 149-155. 10.1016/j.ejpb.2011.09.016.


Osman, K., Evangelopoulos, D., Basavannacharya, C., Gupta, A., McHugh, T.D., Bhakta, S. and Gibbons, S. (2012) An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis. International Journal of Antimicrobial Agents, 39 (2). pp. 124-129. 10.1016/j.ijantimicag.2011.09.018.

Oliveira, G., Hadgraft, J. and Lane, M.E. (2012) Toxicological implications of the delivery of fentanyl from gel extracted from a commercial transdermal reservoir patch. Toxicology in Vitro, 26 (4). pp. 645-648. 10.1016/j.tiv.2012.02.007.


Porta, A., Hsia, Y.F., Doerholt, K., Spyridis, N., Bielicki, J., Menson, E., Tsolia, M., Esposito, S., Wong, I.C.K. and Sharland, M. (2012) Comparing neonatal and paediatric antibiotic prescribing between hospitals: a new algorithm to help international benchmarking. Journal of Antimicrobial Chemotherapy, 67 (5). pp. 1278-1286. 10.1093/jac/dks021.

Patrizi, A., Viltono, L., Frola, E., Harvey, K., Harvey, R.J. and Sassoè-Pognetto, M. (2012) Selective localization of collybistin at a subset of inhibitory synapses in brain circuits. Journal of Comparative Neurology, 520 (1). pp. 130-141. 10.1002/cne.22702.


Rahman, K.M., Tizkova, K., Reszka, A.P., Neidle, S. and Thurston, D.E. (2012) Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries. Bioorganic and Medicinal Chemistry Letters, 22 (8). pp. 3006-3010. 10.1016/j.bmcl.2012.02.020.


Shiu, W.K.P., Rahman, M.M., Curry, J., Stapleton, P.D., Zloh, M., Malkinson, J.P. and Gibbons, S. (2012) Antibacterial Acylphloroglucinols from Hypericum olympicum. Journal of Natural Products, 75 (3). pp. 336-343. 10.1021/np2003319.

Sharma, K., Somavarapu, S., Colombani, A., Govind, N. and Taylor, K.M.G. (2012) Crosslinked chitosan nanoparticle formulations for delivery from pressurized metered dose inhalers. European Journal of Pharmaceutics and Biopharmaceutics, 81 (1). pp. 74-81. 10.1016/j.ejpb.2011.12.014.

Siew, A., Leake, H., Thiovolet, M., Gellert, P., Schatzlein, A.G. and Uchegbu, I.F. (2012) Enhanced Oral Absorption of Hydrophobic and Hydrophilic Drugs Using Quaternary Ammonium Palmitoyl Glycol Chitosan Nanoparticles. Molecular Pharmaceutics, 9 (1). pp. 14-28. 10.1021/mp200469a.

Shah, M.M., Huang, Z. and Martinello, K. (2012) HCN and KV7 (M-) channels as targets for epilepsy treatment. Neuropharmacology . 10.1016/j.neuropharm.2012.03.005.

Stephenson, J.B.P., Harvey, K., Harvey, R.J. and Rees, M.I. (2012) Hyperekplexia: a glycinergic disorder. In: Channelopathies of the nervous system in childhood. MacKeith Press. (In Press)

Snijder, C.A., Kortenkamp, A., Steegers, E.A.P., Jaddoe, V.W.V., Hofman, A., Hass, U. and Burdorf, A. (2012) Intrauterine exposure to mild analgesics during pregnancy and the occurrence of cryptorchidism and hypospadia in the offspring: the Generation R Study. Human Reproduction, 27 (4). pp. 1191-1201. 10.1093/humrep/der474.

Swain, A., Turton, J.A., Scudamore, C., Maguire, D., Pereira, I., Freitas, S., Smyth, R., Munday, M., Stamp, C., Gandhi, M., Sondh, S., Ashall, H., Francis, I., Woodfine, J., Bowles, J. and York, M. (2012) Nephrotoxicity of hexachloro-1:3-butadiene in the male Hanover Wistar rat; correlation of minimal histopathological changes with biomarkers of renal injury. Journal of Applied Toxicology, 32 (6). pp. 417-428. 10.1002/jat.1727.

Soutari, N., Buanz, A.B.M., Gul, M.O., Tuleu, C. and Gaisford, S. (2012) Quantifying crystallisation rates of amorphous pharmaceuticals with dynamic mechanical analysis (DMA). International Journal of Pharmaceutics, 423 (2). pp. 335-340. 10.1016/j.ijpharm.2011.11.010.


Tian, B., Al-Jamal, W.T., Bossche, J. van den and Kostarelos, K. (2012) Design and Engineering of Multifunctional Quantum Dot-Based Nanoparticles for Simultaneous Therapeutic-Diagnostic Applications. Multifunctional Nanoparticles for Drug Delivery Applications (4). pp. 345-365. 10.1007/978-1-4614-2305-8_16.


Uzuner, H., Bauer, R., Fan, T-P., Guo, D., Dias, A., El-Nezami, H., Efferth, T., Williamson, E.M., Heinrich, M., Robinson, N., Hylands, P.J., Hendry, B.M., Cheng, Y-C. and Xu, Q. (2012) Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities. Journal of Ethnopharmacology, 140 (3). pp. 458-468. 10.1016/j.jep.2012.02.028.


Wangteeraprasert, R., Lipipun, V., Gunaratnam, M., Neidle, S., Gibbons, S. and Likhitwitayawuid, K. (2012) Bioactive Compounds from Carissa spinarum. Phytotherapy Research . 10.1002/ptr.4607.


Zeng, Y-H., Osman, K., Xiao, Z-Y., Gibbons, S. and Mu, Q. (2012) Four geranyl-bearing polyisoprenylated benzoylphloroglucinol derivatives from Hypericum sampsonii. Phytochemistry Letters, 5 (1). pp. 200-205. 10.1016/j.phytol.2011.09.009.

This list was generated on Thu May 28 17:52:29 2015 BST.