Items where year is 2012

Up a level
Export as [feed] RSS 2.0 [feed] RSS 1.0 [feed] Atom
Group by: Item Type | Creators | No Grouping
Number of items: 62.

Gill, J.L., Tsai, K.L., Krey, C., Noorai, R.E., Vanbellinghen, J-F., Garosi, L., Shelton, G.D., Clark, L.A. and Harvey, R.J. (2012) A canine BCAN microdeletion associated with episodic falling syndrome. Neurobiology of Disease, 45 (1). pp. 130-136. 10.1016/j.nbd.2011.07.014.

Lalatsa, A., Lee, V.W.Y., Malkinson, J.P., Zloh, M., Schatzlein, A.G. and Uchegbu, I.F. (2012) A Prodrug Nanoparticle Approach for the Oral Delivery of a Hydrophilic Peptide, Leucine5-enkephalin, to the Brain. Molecular Pharmaceutics, 9 (6). pp. 1665-1680. 10.1021/mp300009u.

Heinrich, M., Dhanji, T. and Casselman, I. (2012) Açaí (Euterpe oleracea Mart.). Zeitschrift für Phytotherapie, 33 .

Osman, K., Evangelopoulos, D., Basavannacharya, C., Gupta, A., McHugh, T.D., Bhakta, S. and Gibbons, S. (2012) An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis. International Journal of Antimicrobial Agents, 39 (2). pp. 124-129. 10.1016/j.ijantimicag.2011.09.018.

Liu, Y., Servant, A., Guy, O.J., Al-Jamal, K.T., Williams, P.R., Hawkins, K.M. and Kostarelos, K. (2012) An electric-field responsive microsystem for controllable miniaturised drug delivery applications. Sensors and Actuators B: Chemical . 10.1016/j.snb.2011.12.069. (In Press)

Gibbons, S. (2012) An Introduction to Planar Chromatography and Its Application to Natural Products Isolation. Methods in Molecular Biology (Clifton, N.J.), 864 . pp. 117-153. 10.1007/978-1-61779-624-1_6.

Al-Jamal, K.T., Al-Jamal, W.T., Kostarelos, K., Turton, J.A. and Florence, A.T. (2012) Anti-angiogenic poly-L-lysine dendrimer binds heparin and neutralizes its activity. Results in Pharma Sciences, 2 . pp. 9-15. 10.1016/j.rinphs.2011.12.002.

Shiu, W.K.P., Rahman, M.M., Curry, J., Stapleton, P.D., Zloh, M., Malkinson, J.P. and Gibbons, S. (2012) Antibacterial Acylphloroglucinols from Hypericum olympicum. Journal of Natural Products, 75 (3). pp. 336-343. 10.1021/np2003319.

Gibbons, S. (2012) ‘Legal Highs’ – novel and emerging psychoactive drugs: a chemical overview for the toxicologist. Clinical Toxicology, 50 (1). pp. 15-24. 10.3109/15563650.2011.645952.

Wangteeraprasert, R., Lipipun, V., Gunaratnam, M., Neidle, S., Gibbons, S. and Likhitwitayawuid, K. (2012) Bioactive Compounds from Carissa spinarum. Phytotherapy Research . 10.1002/ptr.4607.

Almeida e Sousa, L., Beezer, A.E., Hansen, L.D., Clapham, D., Connor, J.A. and Gaisford, S. (2012) Calorimetric Determination of Rate Constants and Enthalpy Changes for Zero-Order Reactions. Journal of Physical Chemistry B, 116 (22). pp. 6356-6360. 10.1021/jp302933f.

Porta, A., Hsia, Y.F., Doerholt, K., Spyridis, N., Bielicki, J., Menson, E., Tsolia, M., Esposito, S., Wong, I.C.K. and Sharland, M. (2012) Comparing neonatal and paediatric antibiotic prescribing between hospitals: a new algorithm to help international benchmarking. Journal of Antimicrobial Chemotherapy, 67 (5). pp. 1278-1286. 10.1093/jac/dks021.

Sharma, K., Somavarapu, S., Colombani, A., Govind, N. and Taylor, K.M.G. (2012) Crosslinked chitosan nanoparticle formulations for delivery from pressurized metered dose inhalers. European Journal of Pharmaceutics and Biopharmaceutics, 81 (1). pp. 74-81. 10.1016/j.ejpb.2011.12.014.

Baud, M.G.J., Leiser, T., Haus, P., Samlal, S., Wong, A.C., Wood, R.J., Petrucci, V., Gunaratnam, M., Hughes, S.M., Buluwela, L., Turlais, F., Neidle, S., Meyer-Almes, F-J., White, A.J.P. and Fuchter, M.J. (2012) Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets. Journal of Medicinal Chemistry, 55 (4). pp. 1731-1750. 10.1021/jm2016182.

Tian, B., Al-Jamal, W.T., Bossche, J. van den and Kostarelos, K. (2012) Design and Engineering of Multifunctional Quantum Dot-Based Nanoparticles for Simultaneous Therapeutic-Diagnostic Applications. Multifunctional Nanoparticles for Drug Delivery Applications (4). pp. 345-365. 10.1007/978-1-4614-2305-8_16.

Davies, J.E., Neidle, S. and Taylor, D.G. (2012) Developing and paying for medicines for orphan indications in oncology: utilitarian regulation vs equitable care? British Journal of Cancer, 106 (1). pp. 14-17. 10.1038/bjc.2011.544.

Brucoli, F., Natoli, A., Marimuthu, P., Borrello, M.T., Stapleton, P.D., Gibbons, S. and Schatzlein, A.G. (2012) Efficient synthesis and biological evaluation of proximicins A, B and C. Bioorganic and Medicinal Chemistry, 20 (6). pp. 2019-2024. 10.1016/j.bmc.2012.01.043.

Siew, A., Leake, H., Thiovolet, M., Gellert, P., Schatzlein, A.G. and Uchegbu, I.F. (2012) Enhanced Oral Absorption of Hydrophobic and Hydrophilic Drugs Using Quaternary Ammonium Palmitoyl Glycol Chitosan Nanoparticles. Molecular Pharmaceutics, 9 (1). pp. 14-28. 10.1021/mp200469a.

Abuirmeileh, A., Harkavyi, A., Rampersaud, N., Lever, R., Tadross, J.A., Bloom, S.R. and Whitton, P.S. (2012) Exendin-4 treatment enhances L-DOPA evoked release of striatal dopamine and decreases dyskinetic movements in the 6-hydoxydopamine lesioned rat. Journal of Pharmacy and Pharmacology, 64 (5). pp. 637-643. /10.1111/j.2042-7158.2011.01394.x.

Franklin, B.D., Shebl, N.A. and Barber, N. (2012) Failure mode and effects analysis: too little for too much? BMJ Quality & Safety, 23rd March . 10.1136/bmjqs-2011-000723.

Zeng, Y-H., Osman, K., Xiao, Z-Y., Gibbons, S. and Mu, Q. (2012) Four geranyl-bearing polyisoprenylated benzoylphloroglucinol derivatives from Hypericum sampsonii. Phytochemistry Letters, 5 (1). pp. 200-205. 10.1016/j.phytol.2011.09.009.

Shah, M.M., Huang, Z. and Martinello, K. (2012) HCN and KV7 (M-) channels as targets for epilepsy treatment. Neuropharmacology . 10.1016/j.neuropharm.2012.03.005.

Burnett, S., Franklin, B.D., Moorthy, K., Cooke, M.W. and Vincent, C. (2012) How reliable are clinical systems in the UK NHS? A study of seven NHS organisations. BMJ Quality & Safety . 10.1136/bmjqs-2011-000442.

Stephenson, J.B.P., Harvey, K., Harvey, R.J. and Rees, M.I. (2012) Hyperekplexia: a glycinergic disorder. In: Channelopathies of the nervous system in childhood. MacKeith Press. (In Press)

Cousins, S.L. and Stephenson, F.A. (2012) Identification of N-Methyl-D-aspartic Acid (NMDA) Receptor Subtype-specific Binding Sites That Mediate Direct Interactions with Scaffold Protein PSD-95. Journal of Biological Chemistry, 287 (16). pp. 13465-13476. 10.1074/jbc.M111.292862.

Rahman, K.M., Tizkova, K., Reszka, A.P., Neidle, S. and Thurston, D.E. (2012) Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries. Bioorganic and Medicinal Chemistry Letters, 22 (8). pp. 3006-3010. 10.1016/j.bmcl.2012.02.020.

Moger, J., Garrett, N.L., Begley, D., Mihoreanu, L., Lalatsa, A., Lozano, M.V., Mazza, M., Schatzlein, A.G. and Uchegbu, I.F. (2012) Imaging cortical vasculature with stimulated Raman scattering and two-photon photothermal lensing microscopy. Journal of Raman Spectroscopy, 43 (5). pp. 668-674. 10.1002/jrs.3156.

Murdan, S., Poojary, C., Patel, D.R., Fernandes, J., Haman, A., Saundh, P.S. and Sheikh, Z. (2012) In vivo measurement of the surface energy of human fingernail plates. International Journal of Cosmetic Science, 34 (3). pp. 257-262. 10.1111/j.1468-2494.2012.00711.x.

Snijder, C.A., Kortenkamp, A., Steegers, E.A.P., Jaddoe, V.W.V., Hofman, A., Hass, U. and Burdorf, A. (2012) Intrauterine exposure to mild analgesics during pregnancy and the occurrence of cryptorchidism and hypospadia in the offspring: the Generation R Study. Human Reproduction, 27 (4). pp. 1191-1201. 10.1093/humrep/der474.

Chen, K-H., Mueannoom, W., Gaisford, S. and Kett, V.L. (2012) Investigation into the effect of varying l-leucine concentration on the product characteristics of spray-dried liposome powders. Journal of Pharmacy and Pharmacology . 10.1111/j.2042-7158.2012.01521.x.

Ke, P., Hasegawa, S., Al-Obaidi, H. and Buckton, G. (2012) Investigation of preparation methods on surface/bulk structural relaxation and glass fragility of amorphous solid dispersions. International Journal of Pharmaceutics, 422 (1-2). p. 170. 10.1016/j.ijpharm.2011.10.047.

Falodun, A., Sheng-Xiang, Q., Parkinson, G.N. and Gibbons, S. (2012) Isolation and characterization of a new anticancer diterpenoid from Jatropha gossypifolia. Pharmaceutical Chemistry Journal, 45 (10). pp. 636-639. 10.1007/s11094-012-0693-4.

Gaisford, S. (2012) Isothermal microcalorimetry for quantifying amorphous content in processed pharmaceuticals. Advanced Drug Delivery Reviews, 64 (5). pp. 431-439.

Garrett, N.L., Lalatsa, A., Begley, D., Mihoreanu, L., Uchegbu, I.F., Schatzlein, A.G. and Moger, J. (2012) Label-free imaging of polymeric nanomedicines using coherent anti-stokes Raman scattering microscopy. Journal of Raman Spectroscopy, 43 (5). pp. 681-688. 10.1002/jrs.3170.

Mercer, A., Eastlake, K., Trigg, H. and Thomson, A.M. (2012) Local circuitry involving parvalbumin-positive basket cells in the CA2 region of the hippocampus. Hippocampus, 22 (1). pp. 43-56. 10.1002/hipo.20841.

Campbell, N.H., Karim, N.H.A., Parkinson, G.N., Gunaratnam, M., Petrucci, V., Todd, A.K., Vilar, R. and Neidle, S. (2012) Molecular Basis of Structure–Activity Relationships between Salphen Metal Complexes and Human Telomeric DNA Quadruplexes. Journal of Medicinal Chemistry, 55 (1). pp. 209-222. 10.1021/jm201140v.

James, V.M., Gill, J.L., Topf, M. and Harvey, R.J. (2012) Molecular mechanisms of glycine transporter GlyT2 mutations in startle disease. Biological Chemistry, 393 (4). pp. 283-289. 10.1515/bc-2011-232.

Anderson, C., Bates, I., Brock, T.P., Brown, A.N., Bruno, A., Futter, B., Rennie, T. and Rouse, M.J. (2012) Needs-Based Education in the Context of Globalization. American Journal of Pharmaceutical Education, 76 (4). p. 56. 10.5688/ajpe76456.

Swain, A., Turton, J.A., Scudamore, C., Maguire, D., Pereira, I., Freitas, S., Smyth, R., Munday, M., Stamp, C., Gandhi, M., Sondh, S., Ashall, H., Francis, I., Woodfine, J., Bowles, J. and York, M. (2012) Nephrotoxicity of hexachloro-1:3-butadiene in the male Hanover Wistar rat; correlation of minimal histopathological changes with biomarkers of renal injury. Journal of Applied Toxicology, 32 (6). pp. 417-428. 10.1002/jat.1727.

Innocent, N., Cousins, S.L. and Stephenson, F.A. (2012) NMDA receptor/amyloid precursor protein interactions: A comparison between wild-type and amyloid precursor protein mutations associated with familial Alzheimer's disease. Neuroscience Letters, 515 (2). pp. 131-136. 10.1016/j.neulet.2012.03.029.

Lever, R. and Page, C.P. (2012) Non-anticoagulant Effects of Heparin: An Overview. In: Heparin - A Century of Progress. Handbook of Experimental Pharmacology (207). Springer, pp. 281-305. 10.1007/978-3-642-23056-1_12.

Hancock, R., Bertrand, H.C., Tsujita, T., Naz, S., El-Bakry, A., Laoruchupong, J., Hayes, J.D. and Wells, G. (2012) Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction. Free Radical Biology and Medicine, 52 (2). pp. 444-451. 10.1016/j.freeradbiomed.2011.10.486.

Hancock, R., Bertrand, H.C., Tsujita, T., Naz, S., El-Bakry, A., Laoruchupong, J., Hayes, J.D. and Wells, G. (2012) Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction. Free Radical Biology and Medicine, 52 (2). pp. 444-451. 10.1016/j.freeradbiomed.2011.10.486.

González-Aramundiz, J.V., Lozano, M.V., Sousa-Herves, A., Fernandez-Megia, E. and Csaba, N. (2012) Polypeptides and polyaminoacids in drug delivery. Expert Opinion on Drug Delivery, 9 (2). pp. 183-201. 10.1517/17425247.2012.647906.

Soutari, N., Buanz, A.B.M., Gul, M.O., Tuleu, C. and Gaisford, S. (2012) Quantifying crystallisation rates of amorphous pharmaceuticals with dynamic mechanical analysis (DMA). International Journal of Pharmaceutics, 423 (2). pp. 335-340. 10.1016/j.ijpharm.2011.11.010.

Patrizi, A., Viltono, L., Frola, E., Harvey, K., Harvey, R.J. and Sassoè-Pognetto, M. (2012) Selective localization of collybistin at a subset of inhibitory synapses in brain circuits. Journal of Comparative Neurology, 520 (1). pp. 130-141. 10.1002/cne.22702.

Cong, Y., Pawlisz, E., Bryant, P., Balan, S., Laurine, E., Tommasi, R., Singh, R., Dubey, S., Peciak, K., Bird, M., Sivasankar, A., Swierkosz, J., Muroni, M., Heidelberger, S., Farys, M., Khayrzad, F., Edwards, J., Badescu, G., Hodgson, I., Heise, C., Somavarapu, S., Liddell, J., Powell, K., Zloh, M., Choi, J-W., Godwin, A. and Brocchini, S. (2012) Site-Specific PEGylation at Histidine Tags. Bioconjugate Chemistry, 23 (2). pp. 248-263. 10.1021/bc200530x.

Mercer, A., Botcher, N.A., Eastlake, K. and Thomson, A.M. (2012) SP-SR interneurones: A novel class of neurones of the CA2 region of the hippocampus. Hippocampus . 10.1002/hipo.22010.

Heinrich, M. and Verpoorte, R. (2012) Statistical tools in ethnopharmacology. Journal of Ethnopharmacology, 139 (3). pp. 691-692. 10.1016/j.jep.2011.09.022.

Collie, G.W., Promontorio, R., Hampel, S.M., Micco, M., Neidle, S. and Parkinson, G.N. (2012) Structural Basis for Telomeric G-Quadruplex Targeting by Naphthalene Diimide Ligands. Journal of the American Chemical Society, 134 (5). pp. 2723-2731. 10.1021/ja2102423.

Dürüst, Y., Karakuş, H., Kaiser, M. and Tasdemir, D. (2012) Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles. European Journal of Medicinal Chemistry, 48 . pp. 296-304. 10.1016/j.ejmech.2011.12.028.

Mugglestone, C.J., Mariz, S. and Lane, M.E. (2012) The development and registration of topical pharmaceuticals. International Journal of Pharmaceutics . 10.1016/j.ijpharm.2012.03.052. (In Press)

Jones, B.E., Basit, A.W. and Tuleu, C. (2012) The disintegration behaviour of capsules in fed subjects: A comparison of hypromellose (carrageenan) capsules and standard gelatin capsules. International Journal of Pharmaceutics, 424 (1-2). pp. 40-43. /10.1016/j.ijpharm.2011.12.034.

Franklin, B.D., Rosa, M.B., Miller, G. and Jacklin, A. (2012) The evaluation of a novel model of providing ward pharmacy services. International Journal of Clinical Pharmacy . 10.1007/s11096-012-9650-2.

Murdan, S. (2012) The Nail: Anatomy, Physiology, Diseases and Treatment. In: Topical Nail Products and Ungual Drug Delivery. CRC Press. ISBN 9781439811290. (In Press)

Lepee, C., Klaber, R.E., Benn, J., Fletcher, P.J., Cartoos, P-J., Jacklin, A. and Franklin, B.D. (2012) The use of a consultant-led ward round checklist to improve paediatric prescribing: An interrupted time series study Carole Lépée, Robert E. Klaber, Jonathan Benn, Penny J. Fletcher, Pieter-Jan Cortoos, Ann Jacklin and Bryony Dean Franklin. European Journal of Pediatrics . 10.1007/s00431-012-1751-3Online First™.

Gaisford, S. (2012) Thermal analysis and calorimetry. Advanced Drug Delivery Reviews, 64 (5). p. 383. 10.1016/j.addr.2012.02.010.

Mueannoom, W., Srisongphan, A., Taylor, K.M.G., Hauschild, S. and Gaisford, S. (2012) Thermal ink-jet spray freeze-drying for preparation of excipient-free salbutamol sulphate for inhalation. European Journal of Pharmaceutics and Biopharmaceutics, 80 (1). pp. 149-155. 10.1016/j.ejpb.2011.09.016.

Oliveira, G., Hadgraft, J. and Lane, M.E. (2012) Toxicological implications of the delivery of fentanyl from gel extracted from a commercial transdermal reservoir patch. Toxicology in Vitro, 26 (4). pp. 645-648. 10.1016/j.tiv.2012.02.007.

Uzuner, H., Bauer, R., Fan, T-P., Guo, D., Dias, A., El-Nezami, H., Efferth, T., Williamson, E.M., Heinrich, M., Robinson, N., Hylands, P.J., Hendry, B.M., Cheng, Y-C. and Xu, Q. (2012) Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities. Journal of Ethnopharmacology, 140 (3). pp. 458-468. 10.1016/j.jep.2012.02.028.

Lacerda, L., Russier, J., Pastorin, G., Herrero, M.A., Venturelli, E., Dumortier, H., Al-Jamal, K.T., Prato, M., Kostarelos, K. and Bianco, A. (2012) Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes. Biomaterials, 33 (11). pp. 3334-3343. 10.1016/j.biomaterials.2012.01.024.

Booker, A., Johnston, D. and Heinrich, M. (2012) Value chains of herbal medicines - research needs and key challenges in the context of ethnopharmacology. Journal of Ethnopharmacology . 10.1016/j.jep.2012.01.039.

This list was generated on Fri Oct 31 17:14:53 2014 GMT.